The DOI matches its Crossref record; 30 of the 30 references it cites were found in a registry or an index.
Refined structure of the Hirudin-thrombin complex
Overview
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Integrity signals
Registry
Cites
Statistics
Verification
Claims the paper makes
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Self-check
Percentages, sums and reported differences re-computed from the paper’s own numbers.
The self-check needs the paper’s full text.
Citations
Cites
The interpretation of protein structures: Estimation of static accessibility
Lee, B., & Richards, F. M. (1971) · Journal of Molecular Biology · doi:10.1016/0022-2836(71)90324-x · Cited by 5,850
New Perspectives in Cell Adhesion: RGD and Integrins
Ruoslahti, E., & Pierschbacher, M. D. (1987) · Science · doi:10.1126/science.2821619 · Cited by 4,865
Protein Inhibitors of Proteinases
Laskowski, M., & Kato, I. (1980) · Annual Review of Biochemistry · doi:10.1146/annurev.bi.49.070180.003113 · Cited by 2,230
HUMAN PLASMA PROTEINASE INHIBITORS
Travis, J., & Salvesen, G. S. (1983) · Annual Review of Biochemistry · doi:10.1146/annurev.bi.52.070183.003255 · Cited by 2,104
A graphics model building and refinement system for macromolecules
Jones, T. A. (1978) · Journal of Applied Crystallography · doi:10.1107/s0021889878013308 · Cited by 1,839
Traitement statistique des erreurs dans la determination des structures cristallines
Luzzati, V. (1952) · Acta Crystallographica · doi:10.1107/s0365110x52002161 · Cited by 1,251
Bode, W., Mayr, I., Baumann, U., Huber, R., Stone, S. R., & Hofsteenge, J. (1989) · The EMBO Journal · doi:10.1002/j.1460-2075.1989.tb08511.x · Cited by 888
Self-citationThe detection of sub-units within the crystallographic asymmetric unit
Rossmann, M. G., & Blow, D. M. (1962) · Acta Crystallographica · doi:10.1107/s0365110x62000067 · Cited by 868
The Structure of a Complex of Recombinant Hirudin and Human α-Thrombin
Rydel, T. J., Ravichandran, K. G., Tulinsky, A., Bode, W., Huber, R., Roitsch, C., & Fenton, J. W. (1990) · Science · doi:10.1126/science.2374926 · Cited by 709
Self-citationStructural basis of the activation and action of trypsin
Huber, R., & Bode, W. (1978) · Accounts of Chemical Research · doi:10.1021/ar50123a006 · Cited by 677
Self-citation
Cited by
Principles of docking: An overview of search algorithms and a guide to scoring functions
Halperin, I., Ma, B., Wolfson, H., & Nussinov, R. (2002) · Proteins: Structure, Function, and Bioinformatics · doi:10.1002/prot.10115 · Cited by 1,294
Natural protein proteinase inhibitors and their interaction with proteinases
BODE, W., & HUBER, R. (1992) · European Journal of Biochemistry · doi:10.1111/j.1432-1033.1992.tb16654.x · Cited by 1,043
Self-citationMolecular Recognition of Protein−Ligand Complexes: Applications to Drug Design
Babine, R. E., & Bender, S. L. (1997) · Chemical Reviews · doi:10.1021/cr960370z · Cited by 892
Boron Containing Compounds as Protease Inhibitors
Smoum, R., Rubinstein, A., Dembitsky, V. M., & Srebnik, M. (2012) · Chemical Reviews · doi:10.1021/cr608202m · Cited by 450
A player of many parts: The spotlight falls on thrombin's structure
Stubbs, M. T., & Bode, W. (1993) · Thrombosis Research · doi:10.1016/0049-3848(93)90002-6 · Cited by 441
Self-citation
Metadata
- Authors
- Rydel, T. J., Tulinsky, A., Bode, W., & Huber, R.
- Venue
- Journal of Molecular Biology
- Publisher
- Elsevier BV
- Published
- 1991-09
- Volume
- 221
- Issue
- 2
- Pages
- 583-601
- ISSN
- 0022-2836 (ISSN-L)
- OpenAlex
- W2011214542
- Cited by
- 368
- References
- 30
- FWCI
- 15.78
- Type
- journal article
- Language
- en
- Open access
- closed
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
Are you an author, or do you see a problem with this page? Request a review
How to cite
Cite CoChat for the checks on this page, and the paper for its own findings.
- This page
- CoChat. (2026). Citation check: Refined structure of the Hirudin-thrombin complex. https://app.cochat.ai/papers/10.1016/0022-2836(91)80074-5
- The paper
- Rydel, T. J., Tulinsky, A., Bode, W., & Huber, R. (1991). Refined structure of the Hirudin-thrombin complex. Journal of Molecular Biology. https://doi.org/10.1016/0022-2836(91)80074-5
Data sources
Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.