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Cited by 1,043

The DOI matches its Crossref record; 80 of the 80 references it cites were found in a registry or an index.

Natural protein proteinase inhibitors and their interaction with proteinases

Open access
BODE, Wolfram, HUBER, Robert·1992·European Journal of Biochemistry

Abstract

The substrate‐like ‘canonical' inhibition by the ‘small’ serine proteinase inhibitors and the product‐like inhibition by the carboxypeptidase inhibitor have provided the only atomic models of protein inhibitor–proteinase interactions for about 15 years. The recently published structures of cystatin/stefin – papain complexes and of hirudin – thrombin complexes reveal novel non‐substrate ‐ like interactions. In addition, the structure of pro‐carboxypeptidase showes a mode of inactivation which bears resemblance to proteinase/protein inhibitor systems. Considerable progress in understanding the transition between native and cleaved states of the serpins has also been made by several recent structural studies.

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Crossref · 10.1111/j.1432-1033.1992.tb16654.x

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80 of 80 references verified0 citation errors · 0 not checkable

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Metadata

Authors
BODE, W., & HUBER, R.
Venue
European Journal of Biochemistry
Publisher
Wiley
Published
1992-03
Volume
204
Issue
2
Pages
433-451
ISSN
  • 0014-2956 (ISSN-L)
  • 1432-1033
OpenAlex
W2035567217
Cited by
1,043
References
80
FWCI
25.88
Type
journal article
Language
en
Open access
bronze

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CoChat. (2026). Citation check: Natural protein proteinase inhibitors and their interaction with proteinases. https://app.cochat.ai/papers/10.1111/j.1432-1033.1992.tb16654.x
The paper
BODE, W., & HUBER, R. (1992). Natural protein proteinase inhibitors and their interaction with proteinases. European Journal of Biochemistry. https://doi.org/10.1111/j.1432-1033.1992.tb16654.x

Data sources

Bibliographic data: Semantic Scholar, OpenAlex, Crossref.

Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).

Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.