Remyelination of the superior cerebellar peduncle in old mice following demyelination induced by cuprizone
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Studies of ICI and Swiss Webster mice used 0.5% to 0.6% cuprizone in their diet to induce demyelination.
“Studies of ICI and Swiss Webster mice used 0.5% to 0.6% cuprizone in their diet to induce demyelination 8, 27, 31.”
From SJL Mice Exposed to Cuprizone Intoxication Reveal Strain and Gender Pattern Differences in Demyelination (2009) · cites this paper as [8]
Many ICI and Swiss Webster mice lived for months on the cuprizone diet, though not all tolerated it.
“Though not tolerated by all of these mice, many of them mice lived for months on the cuprizone diet.”
From SJL Mice Exposed to Cuprizone Intoxication Reveal Strain and Gender Pattern Differences in Demyelination (2009) · cites this paper as [8]
Cites
Blakemore, W. F. (1972) · Journal of Neurocytology · doi:10.1007/bf01102943 · Cited by 217 · see citing works
Self-citationDemyelination of the superior cerebellar peduncle in the mouse induced by cuprizone
Blakemore, W. F. (1973) · Journal of the Neurological Sciences · doi:10.1016/0022-510x(73)90118-4 · Cited by 207 · see citing works
Self-citationDemyelination and remyelination after acute spinal cord compression
Gledhill, R. F., Harrison, B. M., & McDonald, W. I. (1973) · Experimental Neurology · doi:10.1016/0014-4886(73)90169-6 · Cited by 181 · see citing works
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Matsushima, G. K., & Morell, P. (2001) · Brain Pathology · doi:10.1111/j.1750-3639.2001.tb00385.x · Cited by 984 · see citing works
Microglial/macrophage accumulation during cuprizone-induced demyelination in C57BL/6 mice
Hiremath, M. M., Saito, Y., Knapp, G. W., Ting, J. P.-Y., Suzuki, K., & Matsushima, G. K. (1998) · Journal of Neuroimmunology · doi:10.1016/s0165-5728(98)00168-4 · Cited by 412 · see citing works
Glial response during cuprizone-induced de- and remyelination in the CNS: lessons learned
Gudi, V., Gingele, S., Skripuletz, T., & Stangel, M. (2014) · Frontiers in Cellular Neuroscience · doi:10.3389/fncel.2014.00073 · Cited by 375 · see citing works
“He also reported about remyelination, which can occur spontaneously after removal of the cuprizone diet (Blakemore, 1973b) and established cuprizone feeding as a model to study de- and remyelination in the superior cerebellar peduncle (Blakemore, 1973a).”
BackgroundMethodInfluentialQuantifying the early stages of remyelination following cuprizone-induced demyelination
Stidworthy, M. F., Genoud, S., Suter, U., Mantei, N., & Franklin, R. J. M. (2003) · Brain Pathology · doi:10.1111/j.1750-3639.2003.tb00032.x · Cited by 224 · see citing works
Taylor, L. C., Gilmore, W., & Matsushima, G. K. (2009) · Brain Pathology · doi:10.1111/j.1750-3639.2008.00230.x · Cited by 84 · see citing works
- Authors
- Blakemore, W. F.
- Affiliations
- University of Cambridge (GB)
- Corresponding author
- Blakemore, W.F.
- Venue
- Journal of the Neurological Sciences
- Publisher
- Elsevier BV
- Published
- 1974-05
- Volume
- 22
- Issue
- 1
- Pages
- 121-126
- ISSN
- 0022-510X (ISSN-L)
- OpenAlex
- W2030013751
- Cited by
- 72
- References
- 3
- Citations by year
- 2025: 1 · 2024: 1 · 2022: 2 · 2021: 1 · 2020: 1 · 2019: 5 · 2017: 2 · 2016: 1 · 2015: 1 · 2014: 1 · 2013: 2 · 2012: 2
- FWCI
- 2.45
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- Journal of the Neurological Sciences (publishedVersion)
- PubMed (publishedVersion)
- Topics
- Health Sciences › Medicine › Pathology and Forensic Medicine › Multiple Sclerosis Research Studies
- Life Sciences › Neuroscience › Developmental Neuroscience › Neurogenesis and neuroplasticity mechanisms
- Life Sciences › Neuroscience › Neurology › Neuroinflammation and Neurodegeneration Mechanisms
- Keywords
- remyelination, superior cerebellar peduncle, cuprizone, demyelination, age effects, oligodendrocyte precursor cells, mouse brain
- MeSH terms
- Age Factors, Animals, Cerebellar Nuclei, Cerebral Ventricles, Cyclohexanes, Demyelinating Diseases, Hydrazones, Male, Nerve Regeneration, Neural Pathways, Remission, Spontaneous, Mice
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