Cited by 33Ovarian function and disordersHypothalamic control of reproductive hormonesReproductive Health and Technologies

Induction of ovulation by combined clomiphene citrate and dexamethasone treatment in clomiphene citrate nonresponders

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Diamant, Y.Z., Evron, S.·1981·European Journal of Obstetrics & Gynecology and Reproductive Biology

Abstract

Fifteen anovulatory, oligomenorrheic, hyperandrogenic and normoprolactinemic women who failed to respond to prolonged clomiphene citrate (CC) treatment, were subsequently treated with CC and small doses of dexamethasone (Dex). Twelve (80%) of the patients ovulated according to BBT and progesterone values, and 7 (49%) conceived during 3--6 treatment cycles. Five of these pregnancies terminated in live, single, full term deliveries, one set of twins and one first trimester abortion. It is concluded that a regimen of combined CC and a small dose of Dex may be offered to CC nonresponders as an effective alternative to Menotropins--HCG treatment.

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Crossref · 10.1016/0028-2243(81)90034-4

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21 of 21 references verified0 citation errors · 0 not checkable

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Authors
Diamant, Y. Z., & Evron, S.
Venue
European Journal of Obstetrics & Gynecology and Reproductive Biology
Publisher
Elsevier BV
Published
1981-04
Volume
11
Issue
5
Pages
335-340
ISSN
  • 0028-2243 (ISSN-L)
  • 0301-2115
OpenAlex
W2155627080
Cited by
33
References
21
Citations by year
2017: 1 · 2012: 1
FWCI
1.81
Type
journal article
Language
en
Open access
Locations
  • European Journal of Obstetrics & Gynecology and Reproductive Biology (publishedVersion)
  • PubMed (publishedVersion)
Topics
  • Health Sciences › Medicine › Reproductive Medicine › Ovarian function and disorders
  • Health Sciences › Medicine › Reproductive Medicine › Hypothalamic control of reproductive hormones
  • Health Sciences › Medicine › Reproductive Medicine › Reproductive Health and Technologies
Keywords
ovulation induction, clomiphene citrate, dexamethasone, anovulation, oligomenorrhea, hyperandrogenism, human menopausal gonadotropin, pregnancy outcomes, live birth, first-trimester abortion
MeSH terms
Adult, Androgens, Anovulation, Clomiphene, Dexamethasone, Drug Resistance, Drug Therapy, Combination, Female, Humans, Infertility, Female, Oligomenorrhea, Ovulation Induction, Pregnancy, Estradiol Congeners

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