The DOI matches its Crossref record; 94 of the 94 references it cites were found in a registry or an index.
“Paradoxical” effects of psychomotor stimulant drugs in hyperactive children from the standpoint of behavioural pharmacology
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“These findings can be interpreted in the light of a hypothesized inverted U-shaped function relating dopamine and noradrenaline activity to performance (Robbins and Sahakian, 1979).”
From A positron emission tomography study of nigro-striatal dopaminergic mechanisms underlying attention: implications for ADHD and its treatment (2013) · cites this paper as Robbins and Sahakian, 1979
In the citing paper
“It is also consistent with a growing literature documenting baseline performance-dependent effects of stimulants and related drugs, which have been explained by a hypothesized inverted U-shaped function, whereby optimal catecholamine levels determine optimal performance, and levels along the curve at either side of the optimum are associated with impaired performance (Robbins and Sahakian, 1979; N”
From A positron emission tomography study of nigro-striatal dopaminergic mechanisms underlying attention: implications for ADHD and its treatment (2013) · cites this paper as Robbins and Sahakian, 1979
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Items 101–170 of 170
Methylphenidate: Rate-dependent drug effects in hyperactive boys
Weber, K. M. (1985) · Psychopharmacology · doi:10.1007/bf00428421 · Cited by 18
Hicks, R. E., Mayo, J. P., & Clayton, C. J. (1989) · International Journal of Neuroscience · doi:10.3109/00207458908986213 · Cited by 18
Does Methylphenidate Induce Overfocusing in Hyperactive Children?
Tannock, R., Schachar, R. J., & Logan, G. D. (1993) · Journal of Clinical Child Psychology · doi:10.1207/s15374424jccp2201_3 · Cited by 15
Methylphenidate affects task-switching and neural signaling in non-human primates
Rajala, A. Z., Populin, L. C., & Jenison, R. L. (2020) · Psychopharmacology · doi:10.1007/s00213-020-05478-z · Cited by 13
“Consistent with our prediction (Rajala et al. 2012; Dyme et al. 1982; Robbins and Sahakian 1979; Tannock and Schachar 1992), the behavioral results of the present study show that MPH hinders taskswitching performance at the 3 mg/kg dose that had been shown to improve performance in the…”
BackgroundResultInfluentialWearables in ADHD: Monitoring and Intervention—Where Are We Now?
Olinic, M.-S., Stretea, R., & Cherecheș, C. (2025) · Diagnostics · doi:10.3390/diagnostics15182359 · Cited by 16
“On the molecular level, ADHD has long been associated with dopaminergic and noradrenergic dysregulation, partly evidenced by the efficacy of stimulant medications that increase synaptic availability of these catecholamines, often ameliorating core symptoms [21,22].”
Stimulants, cognition and ADHD
Baroni, A., & Castellanos, F. X. (2015) · Current Opinion in Behavioral Sciences · doi:10.1016/j.cobeha.2015.04.010 · Cited by 14
“Starting in the 1970s, Sahakian and Robbins [59] and Robbins and Sahakian [60] noted decreased flexibility with stimulants [61], consistent with the Lyon-Robbins hypothesis [62].”
ResultDopamine and Glutamate Interactions in ADHD: Implications for the Future Neuropharmacology of ADHD
Erin, M., Theresa, C., Greg, A., & Paul, E. (2013) · InTech eBooks · doi:10.5772/54207 · Cited by 14
“Treatment with this medication in a variety of experimental paradigms reduced hyper‐ activity [5]; however, of particular note is a study published in 1976 showing decreased hy‐ peractivity when treated with amphetamine in rodents with dopamine depletion [6].”
BackgroundReducing Creativity With Psychostimulants May Debilitate Mental Health and Well-Being
Mohamed, A. D. (2014) · Journal of Creativity in Mental Health · doi:10.1080/15401383.2013.875865 · Cited by 13
“Consistent with this, early research with children diagnosed with attention-deficit hyperactivity disorder (ADHD) reported that methylphenidate (Ritalin) focused attention, and as a tradeoff, it constricted cognitive flexibility in these children (Robbins & Sahakian, 1979).”
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MOTIVATIONAL DIVERSITY AND MESOLIMBIC DOPAMINE: A HYPOTHESIS CONCERNING TEMPERAMENT
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“Psychostimulants exert rate-dependent effects in human subjects with and without attention deficit hyperactivity disorder (ADHD), as well as in measures of locomotor activity in rodent models of ADHD (Robbins and Sahakian 1979; Solanto 1998).”
BackgroundEffects of d-amphetamine on human aggressive responding maintained by avoidance of provocation
Cherek, D. R., Steinberg, J. L., Kelly, T. H., & Sebastian, C. S. (1989) · Pharmacology Biochemistry and Behavior · doi:10.1016/0091-3057(89)90354-7 · Cited by 11
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Where Do We Go from Here? The Importance of Initial Values,
Mehta, M. A. (2002) · Neuropsychopharmacology · doi:10.1016/s0893-133x(02)00359-7 · Cited by 10
“In the interpretation of psychopharmacological studies of cognition, the influence of baseline performance on subsequent response to a drug challenge has been discussed by a number of authors (Robbins and Sahakian 1979; Kimberg et al. 1997; Mattay et al. 2000; Mehta et al. 2000).”
BackgroundSchedule-induced behavior in hyperactive children
Prior, M., Wallace, M. J., & Milton, I. (1984) · Research on Child and Adolescent Psychopathology · doi:10.1007/bf00910665 · Cited by 10
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“This validity is often characterized by 1) the resemblance in symptoms (face validity), 2) shared etiology and underlying pathophysiological mechanisms (construct validity), and 3) similarity of pharmacological responses (predictive validity) (16, 21).”
BackgroundSwerdlow, N. R., Bhakta, S. G., Talledo, J., Benster, L. L., Kotz, J. E., Vinogradov, S., Molina, J. L., & Light, G. A. (2021) · Psychological Medicine · doi:10.1017/s0033291721001239 · Cited by 6
“…identified in AMPH performance-enhancing effects in WIN, QuickSIN and TCT is generally consistent with a large literature reporting inverted-U dose functions for psychostimulant effects on a long list of behavioral measures across species (cf. Lyon & Robbins, 1975; Robbins & Sahakian, 1979).”
Ridley, R. M., Weight, M. L., Haystead, T., & Baker, H. F. (1980) · Psychopharmacology · doi:10.1007/bf00433094 · Cited by 6
“Ridley to a limited range of stimuli (over-focussing) (Robbins and Sahakian 1979).”
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Do Stimulant Medications for Attention-Deficit/Hyperactivity Disorder (ADHD) Enhance Cognition?
Advokat, C. D., & Vinci, C. (2012) · InTech eBooks · doi:10.5772/29889 · Cited by 4
“Pharmacological Research, Vol.62, No. 3, (September 2010 ), pp. 187-206, ISSN1043-6618 Robbins, T.W. & Sahakian, B.J. (1979).”
InfluentialThe Neuropsychopharmacology of Stimulants: Dopamine and ADHD
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“This constitutes a paradoxical impact as it seems counterintuitive given its psycho - stimulant properties (Robbins and Sahakian 1979; Green and Warshauer 1981 ).”
Psychotherapeutic Drugs: A Brief Review of Their Effects on Psychological Processes
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“Although Robbins and Sahakian (1979) suggested that stereotypies may actually improve performance by focusing or channeling attention, they also can impair behavior when flexibility is required.”
BackgroundNEUROPEPTIDE Y (NPY) AND GLUTAMATE TRANSPORTER (GLAST) IN BEHAVIORAL MODELS OF PSYCHIATRIC DISORDERS
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Methylphenidate and Cognitive Performance
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“This was found both for working memory functions (Mehta et al., 2000; Finke et al., 2010; though see Mehta & Riedel, 2006 for different results), motor functions (Robbins & Sahakian, 1979), and decision making (Zack & Poulos, 2009).”
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Metadata
- Authors
- Robbins, T. W., & Sahakian, B. J.
- Affiliations
- University of Cambridge (GB)
- University of Massachusetts Chan Medical School (US)
- Corresponding author
- Robbins, T.W.
- Venue
- Neuropharmacology
- Publisher
- Elsevier BV
- Published
- 1979-12
- Volume
- 18
- Issue
- 12
- Pages
- 931-950
- ISSN
- 0028-3908 (ISSN-L)
- OpenAlex
- W2007634374
- Cited by
- 170
- References
- 93
- Citations by year
- 2026: 1 · 2025: 6 · 2024: 1 · 2023: 2 · 2022: 2 · 2021: 1 · 2020: 2 · 2019: 1 · 2018: 2 · 2017: 3 · 2016: 3 · 2015: 2 · 2014: 6 · 2013: 6 · 2012: 8
- FWCI
- 6.14
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- Neuropharmacology (publishedVersion)
- PubMed (publishedVersion)
- Topics
- Health Sciences › Medicine › Psychiatry and Mental health › Attention Deficit Hyperactivity Disorder
- Life Sciences › Neuroscience › Cellular and Molecular Neuroscience › Neurotransmitter Receptor Influence on Behavior
- Social Sciences › Psychology › Developmental and Educational Psychology › Behavioral and Psychological Studies
- Keywords
- hyperactivity, hyperkinetic disorder, psychostimulants, methylphenidate, amphetamine, rate dependence, attention, cognitive flexibility, stereotypy
- MeSH terms
- Central Nervous System Stimulants, Attention, Behavior, Child, Humans, Hyperkinesis, Social Behavior, Stereotyped Behavior
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