Stimulants, cognition and ADHD
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The effects of stimulant medications impact laboratory measures of executive function less than rated symptoms.
“Interestingly, the effects of stimulant medications impact laboratory measures of executive function less than rated symptoms (Coghill et al., 2014b; Baroni and Castellanos, 2015).”
From Top-Down Dysregulation—From ADHD to Emotional Instability (2016) · cites this paper as Baroni and Castellanos, 2015
Cites
Reaction time variability in ADHD: A meta-analytic review of 319 studies
Kofler, M. J., Rapport, M. D., Sarver, D. E., Raiker, J. S., Orban, S. A., Friedman, L. M., & Kolomeyer, E. G. (2013) · Clinical Psychology Review · doi:10.1016/j.cpr.2013.06.001 · Cited by 648 · see citing works
Comparing the efficacy of stimulants for ADHD in children and adolescents using meta-analysis
Faraone, S. V., & Buitelaar, J. (2010) · European Child & Adolescent Psychiatry · doi:10.1007/s00787-009-0054-3 · Cited by 485 · cited 2× · see citing works
“Introduction For more than 50 years, psychostimulants have been considered prototypical cognitive enhancers [1] and have been used as first-line pharmacologic treatments for Attention-Deficit/Hyperactivity Disorder (ADHD) with overwhelming evidence of their short-term efficacy for the behavioral and subjective symptom…”
BackgroundMotivation Deficit in ADHD is Associated with Dysfunction of the Dopamine Reward Pathway
Volkow, N. D., Wang, G.-J., Newcorn, J. H., Kollins, S. H., Wigal, T. L., Telang, F., Fowler, J. S., Goldstein, R. Z., Klein, N., Logan, J., et al. (2011) · Molecular Psychiatry · doi:10.1038/mp.2010.97 · Cited by 429 · cited 3× · see citing works
“Deficits in motivation are increasingly recognized in individuals with ADHD and they are associated with disruption in dopamine reward circuitry [17 ].”
BackgroundThe cognitive atlas: toward a knowledge foundation for cognitive neuroscience
Poldrack, R. A., Kittur, A., Kalar, D., Miller, E., Seppa, C., Gil, Y., Parker, D. S., Sabb, F. W., & Bilder, R. M. (2011) · Frontiers in Neuroinformatics · doi:10.3389/fninf.2011.00017 · Cited by 385 · see citing works
Sjöwall, D., Roth, L., Lindqvist, S., & Thorell, L. B. (2013) · Journal of Child Psychology and Psychiatry · doi:10.1111/jcpp.12006 · Cited by 359 · cited 1× · see citing works
“Despite a lack of simple assessment measures in children until recently [45], a few studies indicate that emotional dysregulation in ADHD responds to stimulants [16,46–48].”
BackgroundMisuse of Stimulant Medication Among College Students: A Comprehensive Review and Meta-analysis
Benson, K., Flory, K., Humphreys, K. L., & Lee, S. S. (2015) · Clinical Child and Family Psychology Review · doi:10.1007/s10567-014-0177-z · Cited by 328 · see citing works
Volkow, N. D., Wang, G.-J., Fowler, J. S., Telang, F., Maynard, L., Logan, J., Gatley, S. J., Pappas, N., Wong, C., Vaska, P., et al. (2004) · American Journal of Psychiatry · doi:10.1176/appi.ajp.161.7.1173 · Cited by 281 · see citing works
Stimulant <scp>ADHD</scp> medication and risk for substance abuse
Chang, Z., Lichtenstein, P., Halldner, L., D'Onofrio, B., Serlachius, E., Fazel, S., Långström, N., & Larsson, H. (2014) · Journal of Child Psychology and Psychiatry · doi:10.1111/jcpp.12164 · Cited by 225 · cited 2× · see citing works
“Beyond narrowly defined cognitive effects of stimulants Besides the population-based findings from Sweden [13 ,14,36 ], others have also reported improvements in self-reported functioning in those undergoing treatment for ADHD [4,33–35], although the mediators of these effects remain unknown.”
MethodResultAdvokat, C. (2010) · Neuroscience & Biobehavioral Reviews · doi:10.1016/j.neubiorev.2010.03.006 · Cited by 219 · see citing works
Stimulant Medication and Substance Use Outcomes
Humphreys, K. L., Eng, T., & Lee, S. S. (2013) · JAMA Psychiatry · doi:10.1001/jamapsychiatry.2013.1273 · Cited by 211 · cited 1× · see citing works
“A prior meta-analysis (N = 2565) showed that stimulant treatment was neither protective nor harmful in relationship to future substance use [38].”
BackgroundRobbins, T. W., & Sahakian, B. J. (1979) · Neuropharmacology · doi:10.1016/0028-3908(79)90157-6 · Cited by 170 · see citing works
Coghill, D. R., Rhodes, S. M., & Matthews, K. (2007) · Biological Psychiatry · doi:10.1016/j.biopsych.2006.12.030 · Cited by 170 · see citing works
Rösler, M., Retz, W., Fischer, R., Ose, C., Alm, B., Deckert, J., Philipsen, A., Herpertz, S., & Ammer, R. (2010) · The World Journal of Biological Psychiatry · doi:10.3109/15622971003624197 · Cited by 131 · see citing works
Enhancement stimulants: perceived motivational and cognitive advantages
Ilieva, I. P., & Farah, M. J. (2013) · Frontiers in Neuroscience · doi:10.3389/fnins.2013.00198 · Cited by 72 · see citing works
Do stimulants improve functioning in adults with ADHD?
Surman, C. B. H., Hammerness, P. G., Pion, K., & Faraone, S. V. (2013) · European Neuropsychopharmacology · doi:10.1016/j.euroneuro.2012.02.010 · Cited by 47 · see citing works
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Top-Down Dysregulation—From ADHD to Emotional Instability
Petrovic, P., & Castellanos, F. X. (2016) · Frontiers in Behavioral Neuroscience · doi:10.3389/fnbeh.2016.00070 · Cited by 179 · see citing works
“Interestingly, the effects of stimulant medications impact laboratory measures of executive function less than rated symptoms (Coghill et al., 2014b; Baroni and Castellanos, 2015).”
BackgroundSelf-citation
- Authors
- Baroni, A., & Castellanos, F. X.
- Affiliations
- NYU Langone Health (US)
- Nathan Kline Institute for Psychiatric Research (US)
- Corresponding author
- Castellanos, F Xavier
- Venue
- Current Opinion in Behavioral Sciences
- Publisher
- Elsevier BV
- Published
- 2015-08
- Volume
- 4
- Pages
- 109-114
- ISSN
- 2352-1546 (ISSN-L)
- OpenAlex
- W345695947
- Cited by
- 14
- References
- 15
- Citations by year
- 2025: 3 · 2021: 2 · 2020: 1 · 2018: 3 · 2017: 2 · 2016: 3
- FWCI
- 0.37
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- Current Opinion in Behavioral Sciences (publishedVersion)
- Funders
- NIH (T32MH067763)
- Topics
- Health Sciences › Medicine › Psychiatry and Mental health › Attention Deficit Hyperactivity Disorder
- Life Sciences › Neuroscience › Cognitive Neuroscience › Neuroethics, Human Enhancement, Biomedical Innovations
- Life Sciences › Neuroscience › Cellular and Molecular Neuroscience › Neurotransmitter Receptor Influence on Behavior
- Keywords
- attention deficit hyperactivity disorder, psychostimulants, methylphenidate, amphetamine, cognitive enhancement, cognitive function, criminal behavior, traffic accidents, academic performance, substance use prevention, emotion regulation, motivation, Research Domain Criteria, construct validity
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