Cited by 1,074Endometriosis Research and TreatmentMenstrual Health and DisordersMusculoskeletal pain and rehabilitation

The DOI matches its Crossref record; 18 of the 18 references it cites were found in a registry or an index.

Chronic Pelvic Pain: Prevalence, Health-Related Quality of Life, and Economic Correlates

Mathias, S·1996·Obstetrics & Gynecology

Open this paper in CoChat — free account

Abstract

OBJECTIVE: To determine the prevalence of chronic pelvic pain in U.S. women aged 18-50 years, and to examine its association with health-related quality of life, work productivity, and health care utilization. METHODS: In April and May 1994, the Gallup Organization telephoned 17,927 U.S. households to identify women aged 18-50 years who experienced chronic pelvic pain, ie, of at least 6 months' duration. Those who reported chronic pelvic pain were surveyed on severity, frequency, and diagnosis; quality of life; work loss and productivity; and health care utilization. RESULTS: Among 5263 eligible women who agreed to participate, 773 (14.7%) reported chronic pelvic pain within the past 3 months. Those who reported chronic pelvic pain had significantly lower mean scores for general health than those who did not (70.5 versus 78.8,P<.05), and 61% of those with chronic pelvic pain reported that the etiology was unknown. Women diagnosed with endometriosis reported the most health distress, pain during or after intercourse, and interference with activities because of pain. Estimated direct medical costs for outpatient visits for chronic pelvic pain for the U.S population of women aged 18-50 years are $881.5 million per year. Among 548 employed respondents, 15% reported time lost from paid work and 45% reported reduced work productivity. CONCLUSION: Frequently, the cause of chronic pain is undiagnosed, although it affects approximately one in seven U.S. women. Increased awareness of its cost and impact on quality of life should promote increased medical attention to this problem.

Integrity signals

Registry

Crossref · 10.1016/0029-7844(95)00458-0

Cites

18 of 18 references verified0 citation errors · 0 not checkable

Statistics

Recomputing p-values needs the paper’s full text.

Claims the paper makes

This paper’s full text isn’t openly available, so its claims and self-check weren’t run. The registry and citation checks still apply.

Claims other papers make about this one

Each is checked against this paper’s own text: does it say what the citing paper says it does?

Statistical Abstract of the U nited S tates
(2005) · Wiley eBooks · doi:10.1002/0471667196.ess2527 · Cited by 8,872
Measuring Functioning and Well-Being: The Medical Outcomes Study Approach
Stewart, A., & Ware, J. (1992) · doi:10.7249/cb361 · Cited by 2,689
Complications of abdominal and vaginal hysterectomy among women of reproductive age in the United States
Dicker, R. C., Greenspan, J., Strauss, L. T., Cowart, M. R., Scally, M. J., Peterson, H. B., Destefano, F. R., RUBIN, G. L., & Ory, H. W. (1982) · American Journal of Obstetrics and Gynecology · doi:10.1016/0002-9378(82)90362-3 · Cited by 749
Conceptualization and Measurement of Health for Adults in the Health Insurance Study
Stewart, A., Ware, J. E., Brook, R. H., & Davies, A. R. (1978) · Cited by 641
The Prevalence of Dysmenorrhea, Dyspareunia, Pelvic Pain, and Irritable Bowel Syndrome in Primary Care Practices
Jamieson, D. J., & Steege, J. F. (1996) · Obstetrics and Gynecology · doi:10.1016/0029-7844(95)00360-6 · Cited by 439
Relationship of chronic pelvic pain to psychiatric diagnoses and childhood sexual abuse
Walker, E., Katon, W. J., Harrop-Griffiths, J., Holm, L., Russo, J. E., & Hickok, L. R. (1988) · American Journal of Psychiatry · doi:10.1176/ajp.145.1.75 · Cited by 407
Prevalence and genesis of endometriosis
Mahmood, T. A., & Templeton, A. (1991) · Human Reproduction · doi:10.1093/oxfordjournals.humrep.a137377 · Cited by 367
Health Status, Quality of Life, and the Individual
Guyatt, G. H. (1994) · JAMA · doi:10.1001/jama.1994.03520080072047 · Cited by 231
Laparoscopy in 100 women with chronic pelvic pain.
Kresch, A. J., Seifer, D. B., Sachs, L. B., & Barrese, I. (1984) · PubMed · Cited by 231
A randomized clinical trial to compare two different approaches in women with chronic pelvic pain
Peters, A., van Dorst, E. B. L., Jellis, B., van Dorst, E. B. L., Hermans, J. H., & Trimbos, J. (1992) · International Journal of Gynecology & Obstetrics · doi:10.1016/0020-7292(92)90764-a · Cited by 217

Show all 18 references

Sorted by citations

Items 301–400 of 1,000

Does evidence support physiotherapy management of adult female chronic pelvic pain? A systematic review
Loving, S., Nørdling, J., Jaszczak, P., & Thomsen, T. (2012) · Scandinavian Journal of Pain · doi:10.1016/j.sjpain.2011.12.002 · Cited by 37
A cost-effective approach to the management of endometriosis
Winkel, C. A. (2000) · Current Opinion in Obstetrics & Gynecology · doi:10.1097/00001703-200008000-00009 · Cited by 37
Postural changes in women with chronic pelvic pain: a case control study
Montenegro, M. L., Mateus-Vasconcelos, E. C. L., Silva, J. C. R. E., dos Reis, F. J. C., Nogueira, A. A., & Poli‐Neto, O. B. (2009) · BMC Musculoskeletal Disorders · doi:10.1186/1471-2474-10-82 · Cited by 36
“Background Among women, chronic pelvic pain (CPP) is a highly prevalent (2% to 25%) clinical problem [1,2], with substantial costs [3] as well as social and marital repercussions [4,5].”
Background
The relationship between interstitial cystitis and endometriosis in patients with chronic pelvic pain.
Paulson, J. D., & Delgado, M. (2007) · PubMed Central · Cited by 34
Abordagem da dor pélvica crônica em mulheres
Nogueira, A. A., dos Reis, F. J. C., & Poli‐Neto, O. B. (2006) · Revista Brasileira Ginecologia e Obstetrícia · doi:10.1590/s0100-72032006001200008 · Cited by 35
Levator myalgia: why bother?
Adams, K., Gregory, W. T., Osmundsen, B., & Clark, A. (2013) · International Urogynecology Journal · doi:10.1007/s00192-013-2089-8 · Cited by 35
“In women presenting with self-reported chronic pelvic pain approximately 60 % of patients were found to have LM [4, 6].”
Background
Chronic gynaecological pain: an exploration of medical attitudes
Selfe, S. A., van Vugt, M., & Stones, W. R. (1998) · Pain · doi:10.1016/s0304-3959(98)00104-3 · Cited by 34
“Chronic painful conditions such as CPP are a significant burden on medical time and the economic impact of CPP has been emphasised (Mathias et al., 1996).”
Background
Chronic pelvic pain
Beard, R. W. (1998) · BJOG An International Journal of Obstetrics & Gynaecology · doi:10.1111/j.1471-0528.1998.tb09341.x · Cited by 35
Predictors of pain, urinary symptoms and quality of life in patients with chronic pelvic pain syndrome (CPPS): A prospective 12-month follow-up study
Dybowski, C., Löwe, B., & Brünahl, C. (2018) · Journal of Psychosomatic Research · doi:10.1016/j.jpsychores.2018.06.013 · Cited by 34
A possible link between dysmenorrhoea and the development of chronic pelvic pain
Hardi, G., Evans, S., & Craigie, M. J. (2014) · Australian and New Zealand Journal of Obstetrics and Gynaecology · doi:10.1111/ajo.12274 · Cited by 34
High-resolution magnetic resonance-guided posterior femoral cutaneous nerve blocks
Fritz, J. M., Bizzell, C., Kathuria, S., Flammang, A. J., Williams, E. H., Belzberg, A. J., Carrino, J. A., & Chhabra, A. B. (2012) · Skeletal Radiology · doi:10.1007/s00256-012-1553-8 · Cited by 34
Interventional Therapies for Controlling Pelvic Pain: What is the Evidence?
Green, I. C., Cohen, S. L., Finkenzeller, D., & Christo, P. J. (2010) · Current Pain and Headache Reports · doi:10.1007/s11916-009-0089-7 · Cited by 34
“5 billion dollars in health care costs in the United States per year [4].”
Background
Hypofunction of the sympathetic nervous system is an etiologic factor for a wide variety of chronic treatment-refractory pathologic disorders which all respond to therapy with sympathomimetic amines
CHECK, J. H., Cohen, R. L., Katsoff, B., & CHECK, D. L. (2011) · Medical Hypotheses · doi:10.1016/j.mehy.2011.07.024 · Cited by 34
“Chronic pelvic pain is estimated to affect over 5 million women in the United States with an estimated associated healthcare costs of approximately 3 billion dollars per year [28].”
Background
Evolutionary considerations in the development of chronic pelvic pain
Jarrell, J. F., & Arendt‐Nielsen, L. (2016) · American Journal of Obstetrics and Gynecology · doi:10.1016/j.ajog.2016.05.019 · Cited by 34
Emerging therapies and novel approaches to visceral pain
Wesselmann, U., Baranowski, A. P., Börjesson, M., Curran, N., Czakanski, P. P., Giamberardino, M. A., Ness, T. J., Robbins, M. T., & Traub, R. J. (2009) · Drug Discovery Today Therapeutic Strategies · doi:10.1016/j.ddstr.2009.05.001 · Cited by 34
“In the United States, patients suffering from some of these previously un-recognized pain syndromes (such as chronic prostatitis, interstitial cystitis and vulvodynia) have organized patient support groups, which have urged the US government and the National Institutes of Health to fund research studies aimed at a bet…”
BackgroundInfluential
Applying the RE-AIM Framework to Evaluate Integrative Medicine Group Visits Among Diverse Women with Chronic Pelvic Pain
Chao, M. T., ABERCROMBIE, P. D., Santana, T., & Duncan, L. G. (2015) · Pain Management Nursing · doi:10.1016/j.pmn.2015.07.007 · Cited by 35
Prevalence and Use of Complementary Health Approaches among Women with Chronic Pelvic Pain in a Prospective Cohort Study
Chao, M. T., ABERCROMBIE, P. D., Nakagawa, S., Gregorich, S. E., Learman, L. A., & Kuppermann, M. (2014) · Pain Medicine · doi:10.1111/pme.12585 · Cited by 33
“CPP is also associated with substantial societal-level costs, with estimated annual costs of treatments and lost productivity exceeding $2 billion [4, 8].”
Background
The Pelvis and Beyond
Sanses, T. V. D., Chelimsky, G. G., McCabe, N. P., Zolnoun, D., Janata, J. W., Elston, R. C., Buffington, C. A. T., Simpson, P. M., Zhang, L., & Chelimsky, T. C. (2015) · Clinical Journal of Pain · doi:10.1097/ajp.0000000000000307 · Cited by 33
“The present study aimed to (1) determine the feasibility of a detailed pain sensitivity assessment using musculoskeletal TPs in various body locations in women with CPP; and (2) compare possible phenotypic differences and correlations between body locations in patients with MPP or BPS to healthy controls (HC) to gener…”
BackgroundMethod
Hospital-associated Costs of Chronic Pelvic Pain in Canada: A Population-based Descriptive Study
Chen, I., Thavorn, K., Shen, M., Goddard, Y., Yong, P. J., MacRae, G. S., Nishi, C., Matar, A., & Allaire, C. (2017) · Journal of Obstetrics and Gynaecology Canada · doi:10.1016/j.jogc.2016.12.008 · Cited by 33
Multimodal nociceptive mechanisms underlying chronic pelvic pain
Hellman, K. M., Patanwala, I. Y., Pozolo, K. E., & Tu, F. F. (2015) · American Journal of Obstetrics and Gynecology · doi:10.1016/j.ajog.2015.08.038 · Cited by 33
Reliability and validity of a standardized Mensendieck physiotherapy test (SMT)
Haugstad, G. K., Haugstad, T. S., Kirste, U. M., Leganger, S., Hammel, B., Klemmetsen, I., & Malt, U. F. (2006) · Physiotherapy Theory and Practice · doi:10.1080/09593980600822834 · Cited by 33
“In a study from North Carolina, Jamieson and Steege (1996) found that 40% of the patients consulting practicing gynecologists describe such symptoms, and in a study by Mathias (Mathias et al, 1996) 15% of the total female population is referred to as affected.”
Background
Physiotherapy as Empowerment - Treating Women with Chronic Pelvic Pain
Mattsson, M., Wikman, M., Dahlgren, L. G., & Mattsson, B. (2000) · Advances in Physiotherapy · doi:10.1080/14038190050175808 · Cited by 32
“In a US Gallup study 14% of middle-aged women reported such pain experiences (1) and CPP is said to account for about 10% of outpatient gynaecological visits in the US (2).”
Background
Evidence for the role of mast cells in colon–bladder cross organ sensitization
Fitzgerald, J. J., Ustinova, E. E., Koronowski, K. B., de Groat, W. C., & Pezzone, M. A. (2012) · Autonomic Neuroscience · doi:10.1016/j.autneu.2012.09.002 · Cited by 32
“Introduction Women experiencing chronic pelvic pain often exhibit overlapping symptoms of interstitial cystitis (IC) and irritable bowel syndrome (IBS) (Mathias et al., 1996).”
BackgroundInfluential
Transvaginal Trigger Point Injections Improve Pain Scores in Women with Pelvic Floor Hypertonicity and Pelvic Pain Conditions
Bartley, J. M., Han, E., Gupta, P., Gaines, N., Killinger, K. A., Boura, J., Farrah, M., Gilleran, J., Sirls, L. T., II, & Peters, K. M. (2018) · Urogynecology · doi:10.1097/spv.0000000000000581 · Cited by 32
“C hronic pelvic pain affects 1 in 7 women in the United States and can have significant physical, emotional, and psychological effects.(1) Although the exact cause of pelvic pain varies, a common clinical definition is pelvic pain that is noncyclical and occurring for at least 6 months.”
Background
Using magnetic resonance phase-contrast velocity mapping for diagnosing pelvic congestion syndrome
Meneses, L. Q., Uribe, S. A., Cristián Tejos, N., Andía, M. E., Fava, M. P., & Pablo Irarrázaval, M. (2011) · Phlebology The Journal of Venous Disease · doi:10.1258/phleb.2010.010049 · Cited by 32
Pelvic pain: A chronic visceral pain syndrome
Wesselmann, U., & Czakanski, P. P. (2001) · Current Pain and Headache Reports · doi:10.1007/s11916-001-0005-2 · Cited by 32
Pelvic pain and surgeries in women before interstitial cystitis/painful bladder syndrome
LANGENBERG, P. W., Wallach, E. E., Clauw, D. J., Howard, F. M., Diggs, C., Wesselmann, U., Greenberg, P., & Warren, J. W. (2009) · American Journal of Obstetrics and Gynecology · doi:10.1016/j.ajog.2009.10.866 · Cited by 31
The role of nonpharmacologic therapies in management of chronic pelvic pain: what to do when surgery fails
Till, S. R., Wahl, H. N., & As‐Sanie, S. (2017) · Current Opinion in Obstetrics & Gynecology · doi:10.1097/gco.0000000000000376 · Cited by 31
Therapeutic Approaches of Botulinum Toxin in Gynecology
Moga, M., Dimienescu, O. G., Bălan, A., Scârneciu, I., Barna, B., & Pleș, L. (2018) · Toxins · doi:10.3390/toxins10040169 · Cited by 31
A bibliometric analysis of obstetrics and gynecology articles with highest relative citation ratios, 1980 to 2019
Mitra, A. N., Aurora, N., Grover, S., Ananth, C. V., & Brandt, J. S. (2020) · American Journal of Obstetrics & Gynecology MFM · doi:10.1016/j.ajogmf.2020.100293 · Cited by 32
Subcutaneous Peripheral Nerve Stimulation Treatment for Chronic Pelvic Pain
Tamimi, M. A., Davids, H. R., Barolat, G., Krutsch, J. P., & Ford, T. (2008) · Neuromodulation Technology at the Neural Interface · doi:10.1111/j.1525-1403.2008.00176.x · Cited by 31
“The prevalence rate of pelvic pain in primary-care practices in one report was 39% (3).”
Background
Transvaginal Ultrasound Examination of Women With and Without Pelvic Venous Congestion
Halligan, S., Campbell, D., Bartram, C. I., Rogers, V., EL-HADDAD, C., Patel, S., & Beard, R. W. (2000) · Clinical Radiology · doi:10.1053/crad.2000.0602 · Cited by 31
Health Services for Women with Chronic Pelvic Pain
Stones, W. R., & Price, C. (2002) · Journal of the Royal Society of Medicine · doi:10.1258/jrsm.95.11.531 · Cited by 60
Evaluation of clinical practice guidelines (CPG) on the management of female chronic pelvic pain (CPP) using the AGREE II instrument
Ghai, V., Subramanian, V., Jan, H., Loganathan, J., & Doumouchtsis, S. K. (2021) · International Urogynecology Journal · doi:10.1007/s00192-021-04848-1 · Cited by 30
Prevalence of pelvic pain in transgender individuals on testosterone
Grimstad, F. W., Boskey, E. R., Clark, R. S., & Ferrando, C. A. (2023) · The Journal of Sexual Medicine · doi:10.1093/jsxmed/qdad135 · Cited by 30
The effects of mode of delivery and time since birth on chronic pelvic pain and health-related quality of life
Li, W.-Y., Liabsuetrakul, T., Stray‐Pedersen, B., Li, Y., Guo, L.-J., & Qin, W.-Z. (2013) · International Journal of Gynecology & Obstetrics · doi:10.1016/j.ijgo.2013.07.029 · Cited by 30
“The negative effects of cesarean delivery and CPP on HRQoL in the present study are in agreement with previous results [3,4,20], although different measurements were used.”
BackgroundResult
Intermenstrual Pelvic Pain, Quality of Life and Mood
Grandi, G., Xholli, A., Ferrari, S., Cannoletta, M., Volpe, A., & Cagnacci, A. (2012) · Gynecologic and Obstetric Investigation · doi:10.1159/000343997 · Cited by 31
Épidémiologie et aspects économiques des douleurs pelvipérinéales chroniques
Sibert, L., Rigaud, J., Delavierre, D., & Labat, J.-J. (2010) · The French Journal of Urology · doi:10.1016/j.purol.2010.08.004 · Cited by 30
Chronic pelvic pain and quality of life after laparoscopy
Cox, L., Ayers, S., Nala, K., & Penny, J. (2006) · European Journal of Obstetrics & Gynecology and Reproductive Biology · doi:10.1016/j.ejogrb.2006.04.020 · Cited by 30
“CPP is associated with symptoms of depression, anxiety, low quality of life, low productivity, decreased energy, sexual dysfunction and relationship problems [5,6].”
Background
A retrospective claims database analysis to assess patterns of interstitial cystitis diagnosis
Wu, E. Q., Birnbaum, H. G., Kang, Y. J., Parece, A., Mallett, D. A., Taitel, H., & Evans, R. J. (2006) · Current Medical Research and Opinion · doi:10.1185/030079906x80431 · Cited by 29
A disorder of sympathomimetic amines leading to increased vascular permeability may be the etiologic factor in various treatment refractory health problems in women
Check, J. H., Katsoff, D., Kaplan, H., Liss, J., & Boimel, P. J. (2007) · Medical Hypotheses · doi:10.1016/j.mehy.2007.05.052 · Cited by 29
“Chronic pelvic pain affects approximately 15% of the adult female population [12].”
Background
Predictors of Depression, Anxiety and Stress Indicators in a Cohort of Women with Chronic Pelvic Pain
Brooks, T., Sharp, R., Evans, S., Baranoff, J. A., & Esterman, A. (2020) · Journal of Pain Research · doi:10.2147/jpr.s223177 · Cited by 29
A systematic review on reported outcomes and outcome measures in female idiopathic chronic pelvic pain for the development of a core outcome set
Ghai, V., Subramanian, V., Jan, H., Pergialiotis, V., Thakar, R., & Doumouchtsis, S. K. (2020) · BJOG An International Journal of Obstetrics & Gynaecology · doi:10.1111/1471-0528.16412 · Cited by 29
Adhesion formation after peritoneoscopy with liver biopsy in a survival porcine model: comparison of laparotomy, laparoscopy, and transgastric natural orifice transluminal endoscopic surgery (NOTES)
Dubcenco, E., Assumpcao, L., Dray, X., Gabrielson, K. L., Ruben, D., Pipitone, L., Donatelli, G., Krishnamurty, D. M., Baker, J. P., Marohn, M. R., et al. (2009) · Endoscopy · doi:10.1055/s-0029-1215229 · Cited by 29
Improvement in chronic pelvic pain after gonadotropin releasing hormone analogue (GnRH-a) administration in premenopausal women suffering from adenomyosis or endometriosis: a retrospective study
Morelli, M., Rocca, M. L., Venturella, R., Mocciaro, R., & Zullo, F. (2013) · Gynecological Endocrinology · doi:10.3109/09513590.2012.743017 · Cited by 29
“Direct costs are related to expenses for diagnosis and hospitalization for pain, whereas indirect costs are secondary to impaired health-related quality of life, diminished psychological and social functioning [4,9,10] and lost work productivity [4].”
Background
Systematic Review of Therapies for Noncyclic Chronic Pelvic Pain in Women
Yunker, A., Sathe, N. A., Reynolds, W. M., Likis, F. E., & Andrews, J. (2012) · Obstetrical & Gynecological Survey · doi:10.1097/ogx.0b013e31825cecb3 · Cited by 29
“In addition, the total indirect cost due to time lost from work is estimated to be $760 million per year (adjusted for inflation from $555 million in 1996).(7) Chronic pelvic pain carries a significant quality of life burden in sexual functioning, depression, fatigue, and physical limitations and disability associated…”
Background
A cognitive behavioural based assessment of women with chronic pelvic pain
Weijenborg, P. T. M., ter Kuile, M. M., & Stones, W. R. (2009) · Journal of Psychosomatic Obstetrics & Gynecology · doi:10.3109/01674820903378742 · Cited by 29
Late post-partum dyspareunia: Does delivery play a role?
Fauconnier, A., Goltzene, A., Issartel, F., Jansé-Marec, J., Blondel, B., & Fritel, X. (2012) · The French Journal of Urology · doi:10.1016/j.purol.2012.01.008 · Cited by 28
Imaging findings of pelvic venous insufficiency in patients with postural orthostatic tachycardia syndrome
Knuttinen, M.-G., Zurcher, K. S., Khurana, N., Patel, I. J., Foxx–Orenstein, A. E., Harris, L. A., Lawrence, A., Aguilar, F., Sichlau, M. J., Smith, B. H., et al. (2020) · Phlebology The Journal of Venous Disease · doi:10.1177/0268355520947610 · Cited by 28
Sacral nerve modulation in the treatment of chronic pain after pelvic surgery
Martellucci, J., Naldini, G., POPOLO, G. D., & Carriero, A. (2011) · Colorectal Disease · doi:10.1111/j.1463-1318.2011.02659.x · Cited by 28
Prise en charge de l'endométriose: évaluation clinique et biologique
Panel, P., & Renouvel, F. (2007) · Journal de gynécologie, obstétrique et biologie de la reproduction. Supplément/Journal de gynécologie obstétrique et biologie de la reproduction · doi:10.1016/j.jgyn.2006.12.020 · Cited by 28
“[2] Mathias SD, Kuppermann M, Liberman RF, Lipschutz RC, Steege JF.”
Pelvic pain in urogynaecology. Part I: evaluation, definitions and diagnoses
Kavvadias, T., Baeßler, K., & Schuessler, B. (2010) · International Urogynecology Journal · doi:10.1007/s00192-010-1218-x · Cited by 28
“Fifteen to twenty percent of women have experienced pelvic pain of longer than 1 year’s duration and 61% of them report that the cause of their pain is unknown [1, 2 ].”
Background
Chronic pelvic pain: Pathogenesis and validated assessment
Yosef, A. H., Ahmed, A. G. M., Al-Hussaini, T. K., Abdellah, M. S., Cua, G., & Bedaiwy, M. A. (2016) · Middle East Fertility Society Journal · doi:10.1016/j.mefs.2016.08.001 · Cited by 28
Researching what matters to improve chronic pain care in Canada: A priority-setting partnership process to support patient-oriented research
Poulin, P. A., Shergill, Y., Romanow, H. C., Busse, J. W., Chambers, C. T., Cooper, L., Forgeron, P. A., Harper, A. O., Hudspith, M., Iorio, A., et al. (2018) · Canadian Journal of Pain · doi:10.1080/24740527.2018.1433959 · Cited by 28
Patients with chronic pelvic pain: endometriosis or interstitial cystitis/painful bladder syndrome?
Butrick, C. W. (2007) · PubMed Central · Cited by 28
Dynamic weight bearing as a non‐reflexive method for the measurement of abdominal pain in mice
Laux‐Biehlmann, A., Boyken, J., Dahllöf, H., Schmidt, N., Zollner, T. M., & Nagel, J. (2015) · European Journal of Pain · doi:10.1002/ejp.800 · Cited by 28
“This model might provide a tool with high translational value for addressing CPP diseases in women.”
BackgroundInfluential
Current usage of qualitative research in female pelvic pain: a systematic review
Mellado, B. H., Pilger, T. L., Poli‐Neto, O. B., Silva, J. C. R. E., Nogueira, A. A., & dos Reis, F. J. C. (2019) · Archives of Gynecology and Obstetrics · doi:10.1007/s00404-019-05212-x · Cited by 26
A digital wireless system for closed-loop inhibition of nociceptive signals
Zuo, C., Yang, X., Wang, Y., Hagains, C. E., Li, A.-L., Peng, Y. B., & Chiao, J.-C. (2012) · Journal of Neural Engineering · doi:10.1088/1741-2560/9/5/056010 · Cited by 26
Attributes and Barriers to Care of Pelvic Pain in University Women
Mann, J., Shuster, J. J., & Moawad, N. S. (2013) · Journal of Minimally Invasive Gynecology · doi:10.1016/j.jmig.2013.05.003 · Cited by 28
“Interestingly, Mathias et al also found that women with endometriosis reported the most distress relating to pain and its interference with daily activities.”
BackgroundResultInfluential
Neuromodulation of the Dorsal Root Ganglion for Chronic Postsurgical Pain
Antony, A. B., Schultheis, B. C., Jolly, S. M., Bates, D., Hunter, C., & Levy, R. M. (2019) · Pain Medicine · doi:10.1093/pm/pnz072 · Cited by 26
“Chronic pelvic pain (CPP) is a debilitating, highly prevalent, and costly condition that affects up to 25–40% of both men and women all over the world [42].”
Background
Presentation patterns in women with pelvic venous disorders differ based on age of presentation
Sulakvelidze, L., Tran, M., KENNEDY, R. J., Lakhanpal, S., & Pappas, P. J. (2020) · Phlebology The Journal of Venous Disease · doi:10.1177/0268355520954688 · Cited by 26
“The differential diagnosis for chronic pelvic pain (CPP) in women is extensive, and idiopathic in up to 60% of cases (see Table 2).(19,20) In our previous publication, we reported that the vast majority of patients with PVI have an iliac vein outflow obstruction with or without ovarian vein reflux as the cause of thei…”
Background
Myofascial Pelvic Pain
Kotarinos, R. K. (2012) · Current Pain and Headache Reports · doi:10.1007/s11916-012-0277-8 · Cited by 26
“It is estimated that chronic pelvic pain affects up to 15 % of women in the USA and the UK [2, 3].”
Background
Effects of Transcranial Direct Current Stimulation, Transcranial Pulsed Current Stimulation, and Their Combination on Brain Oscillations in Patients with Chronic Visceral Pain: A Pilot Crossover Randomized Controlled Study
Thibaut, A., Russo, C., Puerto, A. M. H., Morales-Quezada, J. L., Deitos, A., Petrozza, J. C., Freedman, S. D., & Fregni, F. (2017) · Frontiers in Neurology · doi:10.3389/fneur.2017.00576 · Cited by 26
Interstitial cystitis in persistent posthysterectomy chronic pelvic pain.
Chung, M. K. (2004) · PubMed Central · Cited by 26
Parental rearing style, premorbid personality, mental health, and quality of life in chronic regional pain: A causal analysis
Lung, F., Huang, Y.-L., Shu, B., & Fei-Yin, L. (2004) · Comprehensive Psychiatry · doi:10.1016/j.comppsych.2004.02.009 · Cited by 26
Reproducible assessment of vaginal and rectal mucosal and skin blood flow: laser doppler fluximetry of the pelvic microcirculation
Emmanuel, A. V., Kamm, M. A., & Beard, R. W. (2000) · Clinical Science · doi:10.1042/cs0980201 · Cited by 26
The efficacy of alum-containing ferrous thermal water in the management of chronic inflammatory gynaecological disorders—A randomized controlled study
Zámbó, L., Dékány, M., & Bender, T. (2008) · European Journal of Obstetrics & Gynecology and Reproductive Biology · doi:10.1016/j.ejogrb.2008.03.015 · Cited by 26
Laparoscopic and Psychologic Evaluation of Women with Chronic Pelvic Pain
Richter, H. E., Holley, R. L., Chandraiah, S., & Varner, R. E. (1998) · The International Journal of Psychiatry in Medicine · doi:10.2190/a2k2-g7j5-mnbq-bnde · Cited by 26
Office Assessment of Chronic Pelvic Pain
Steege, J. F. (1997) · Clinical Obstetrics & Gynecology · doi:10.1097/00003081-199709000-00016 · Cited by 26
Application of botulinum toxin in pregnancy and its impact on female reproductive health
Li, W., & Tang, M. J. (2019) · Expert Opinion on Drug Safety · doi:10.1080/14740338.2020.1707803 · Cited by 25
Chronic pelvic pain and endometriosis in adolescents
Solnik, M. J. (2006) · Current Opinion in Obstetrics & Gynecology · doi:10.1097/01.gco.0000242953.94749.2b · Cited by 26
Endovascular intervention for pelvic congestion syndrome is justified for chronic pelvic pain relief and patient satisfaction
Thors, A., Haurani, M. J., Gregio, T. K., & Go, M. R. (2014) · Journal of Vascular Surgery Venous and Lymphatic Disorders · doi:10.1016/j.jvsv.2013.12.002 · Cited by 25
Osteopathy for Endometriosis and Chronic Pelvic Pain – a Pilot Study
Sillem, M., Juhasz‐Böss, I., Klausmeier, I., Mechsner, S., Siedentopf, F., & Solomayer, E. (2016) · Geburtshilfe und Frauenheilkunde · doi:10.1055/s-0042-111010 · Cited by 25
Musculoskeletal Dysfunctions in Patients With Chronic Pelvic Pain: A Preliminary Descriptive Survey
Mieritz, R. M., Thorhauge, K., Forman, A., Mieritz, H. B., Hartvigsen, J., & Christensen, H. W. (2016) · Journal of Manipulative and Physiological Therapeutics · doi:10.1016/j.jmpt.2016.09.003 · Cited by 25
Pelvic Pain and Associated Characteristics Among Women in Northern Mexico
García‐Pérez, H., Harlow, S. D., Erdmann, C. A., & Denman, C. A. (2010) · International Perspectives on Sexual and Reproductive Health · doi:10.1363/3609010 · Cited by 25
Multicentre retrospective study to assess diagnostic accuracy of ultrasound for superficial endometriosis—Are we any closer?
Chowdary, P., Stone, K., Ma, T., Readman, E., McIlwaine, K., Druitt, M. L., Ellett, L., Cameron, M. S., & Maher, P. J. (2018) · Australian and New Zealand Journal of Obstetrics and Gynaecology · doi:10.1111/ajo.12911 · Cited by 25
Multi-Center Studies of the Global Impact of Endometriosis and the Predictive Value of Associated Symptoms
Nnoaham, K. E., Sivananthan, S., Hummelshøj, L., Jenkinson, C., Webster, P., Kennedy, S., & Zondervan, K. T. (2009) · Journal of Endometriosis and Pelvic Pain Disorders · doi:10.1177/228402650900100106 · Cited by 27
Before the onset of interstitial cystitis/bladder pain syndrome, the presence of multiple non-bladder syndromes is strongly associated with a history of multiple surgeries
Warren, J. W., Morozov, V., Howard, F. M., Wesselmann, U., Gallicchio, L. M., LANGENBERG, P. W., & Clauw, D. J. (2013) · Journal of Psychosomatic Research · doi:10.1016/j.jpsychores.2013.10.013 · Cited by 26
Chronic pelvic pain: the occurrence of interstitial cystitis in a gynecological population.
Paulson, J. D., & Delgado, M. (2005) · PubMed Central · Cited by 25
Cognitive Behavioral Therapy for Chronic Pelvic Pain: What Is It and Does It Work?
Lackner, J. M., Clemens, J. Q., Radziwon, C. D., Danforth, T. L., Ablove, T. S., Krasner, S. S., Vargovich, A. M., O’Leary, P. C., Marotto, T., & Naliboff, B. D. (2024) · The Journal of Urology · doi:10.1097/ju.0000000000003847 · Cited by 28
“8 The associated disease burden 7,9 leaves UCPPS patients, 10,11 providers, 12 employers, and payers largely dissatis-ﬁed, seeking more effective treatment options.”
Background
Medical, surgical and alternative treatments for chronic pelvic pain in women: a descriptive review
Vercellini, P., Viganò, P., Somigliana, E., Abbiati, A., Barbàra, G., & Fedele, L. (2009) · Gynecological Endocrinology · doi:10.1080/09513590802530940 · Cited by 24
“An estimated 274 million dollars is spent annually on the management of this condition in the UK National Health System [8] and 881 millions a year on its outpatient management in the US [7].”
Background
Inflammation and Chronic Pelvic Pain: A Biological Trigger for Depression in Women?
Graziottin, A. (2014) · Journal of Depression & Anxiety · doi:10.4172/2167-1044.1000142 · Cited by 23
“Of note, women experiencing CPP often exhibit overlapping symptoms of BPS/IC and IBS [76].”
BackgroundInfluential
Neuromodulation for Chronic Pelvic Pain
Tam, J., Loeb, C. A., Grajower, D., Kim, J., & Weissbart, S. J. (2018) · Current Urology Reports · doi:10.1007/s11934-018-0783-2 · Cited by 24
Botulinum Toxin-A Injection in Chronic Pelvic Pain Syndrome Treatment: A Systematic Review and Pooled Meta-Analysis
Panunzio, A., Tafuri, A., Mazzucato, G., Cerrato, C., Orlando, R., Pagliarulo, V., Antonelli, A., & Cerruto, M. A. (2022) · Toxins · doi:10.3390/toxins14010025 · Cited by 24
“7%, and in more than half of cases the etiology was unknown [4].”
Background
Painful Intercourse Is Significantly Associated with Evoked Pain Perception and Cognitive Aspects of Pain in Women with Pelvic Pain
Alappattu, M. J., George, S. Z., Robinson, M. E., Fillingim, R. B., Moawad, N. S., LeBrun, E. E. W., & Bishop, M. D. (2014) · Sexual Medicine · doi:10.1002/sm2.52 · Cited by 24
Providing Holistic Care for Women with Chronic Pelvic Pain
ABERCROMBIE, P. D., & Learman, L. A. (2012) · Journal of Obstetric, Gynecologic & Neonatal Nursing · doi:10.1111/j.1552-6909.2012.01403.x · Cited by 23
Physical therapy management of female chronic pelvic pain: Anatomic considerations
George, S. E., Clinton, S. C., & Borello‐France, D. (2012) · Clinical Anatomy · doi:10.1002/ca.22187 · Cited by 24
“In a study by Mathias et al. (1996), 15% of surveyed women indicated CPP with these women indicating lower general health compared to those without CPP.”
Result
Neurolytic block of ganglion of Walther for the management of chronic pelvic pain.
Malec‐Milewska, M., Horosz, B., Kolęda, I., Sękowska, A., Kucia, H., Kosson, D., & Jakiel, G. (2014) · Videosurgery and Other Miniinvasive Techniques · doi:10.5114/wiitm.2014.43079 · Cited by 24
“Chronic pelvic pain (CPP) is a challenge to the treating physician and given its prevalence of 15% in women aged 18–50 years it is likely to be encountered in gynecological practice [1].”
Botulinum neurotoxin type A injection of the pelvic floor muscle in pain due to spasticity: a review of the current literature
Bhide, A., Puccini, F., Khullar, V., Elneil, S., & Digesu, G. A. (2013) · International Urogynecology Journal · doi:10.1007/s00192-012-2015-5 · Cited by 24
Islamic food laws: philosophical basis and practical implications
Chaudry, M. M. (1992) · Cited by 24
The role of appendectomy at the time of laparoscopic surgery for benign gynecologic conditions
Peters, A., & Mansuria, S. M. (2018) · Current Opinion in Obstetrics & Gynecology · doi:10.1097/gco.0000000000000466 · Cited by 23
Presence of endometriosis and chronic overlapping pain conditions negatively impacts the pain experience in women with chronic pelvic–abdominal pain: A cross-sectional survey
Bartley, E. J., Alappattu, M. J., Manko, K., Lewis, H., Vasilopoulos, T., & Lamvu, G. (2024) · Women s Health · doi:10.1177/17455057241248017 · Cited by 24
Psychosomatische Aspekte des chronischen Unterbauchschmerzsyndroms
Brünahl, C. A., Riegel, B., Höink, J., Kutup, A., Eichelberg, E., & Löwe, B. (2014) · Der Schmerz · doi:10.1007/s00482-014-1422-6 · Cited by 23
Relationship Between Pain and Quality of Life
Farahani, M. A., & Assari, S. (2009) · Springer eBooks · doi:10.1007/978-0-387-78665-0_229 · Cited by 23
Non-health-care costs associated with endometriosis
Simoens, S., Meuleman, C., & D’Hooghe, T. M. (2011) · Human Reproduction · doi:10.1093/humrep/der215 · Cited by 23
“For instance, estimates of the number of hours missed from work because of endometriosis ranged from 19.2 to 86.4 h per patient per year (Kunz et al., 1995; Mathias et al., 1996).”
BackgroundInfluential
An osteopathic approach to treating women with chronic pelvic pain.
Tettambel, M. A. (2005) · PubMed · Cited by 23
Evaluation of the levator ani and pelvic wall muscles in levator ani syndrome.
Hull, M., & Corton, M. M. (2009) · PubMed · Cited by 23
History of childhood maltreatment and symptoms of anxiety and depression in women with chronic pelvic pain
Poli‐Neto, O. B., Tawasha, K. A. S., Romão, A. P. M. S., Hisano, M. K., Moriyama, A., dos Reis, F. J. C., Silva, J. C. R. E., & Nogueira, A. A. (2017) · Journal of Psychosomatic Obstetrics & Gynecology · doi:10.1080/0167482x.2017.1306515 · Cited by 26
“In addition to having a negative impact on the quality of life of women, CPP has a considerable economic impact of approximately three billion dollars per year, of which two-thirds are out-of-pocket expenses [4,5].”
Background
Diagnostic Evaluation of Chronic Pelvic Pain
Khatri, G., Khan, A., Raval, G., & Chhabra, A. B. (2017) · Physical Medicine and Rehabilitation Clinics of North America · doi:10.1016/j.pmr.2017.03.004 · Cited by 22
“7% of reproductive-age women.(2) Chronic pelvic pain may stem from causes related to native pelvic organs, pelvic floor dysfunction and prolapse, synthetic material placed in the pelvis for treatment of prolapse or urinary incontinence, or neuromuscular causes.”
Background
Treatment of Chronic Refractory Neuropathic Pelvic Pain with High‐Frequency 10‐kilohertz Spinal Cord Stimulation
Simopoulos, T. T., Yong, R. J., & Gill, J. (2017) · Pain Practice · doi:10.1111/papr.12656 · Cited by 22

Authors: Mathias, S.
Affiliations: University of North Carolina at Chapel Hill (US)
Corresponding author: Mathias, S
ORCID: Mathias, S
Venue: Obstetrics & Gynecology
Publisher: Ovid Technologies (Wolters Kluwer Health)
Published: 1996-03
Volume: 87
Issue: 3
Pages: 321-327
ISSN: 0029-7844 (ISSN-L)
DOI: 10.1016/0029-7844(95)00458-0
OpenAlex: W1985935279
Cited by: 1,074
References: 18
Citations by year: 2026: 16 · 2025: 36 · 2024: 29 · 2023: 49 · 2022: 36 · 2021: 45 · 2020: 37 · 2019: 39 · 2018: 50 · 2017: 53 · 2016: 46 · 2015: 38 · 2014: 55 · 2013: 37 · 2012: 51
FWCI: 11.94
Type: journal article
Language: en
Open access: closed
Locations: Obstetrics and Gynecology (publishedVersion)
PubMed (publishedVersion)
Topics: Health Sciences › Medicine › Reproductive Medicine › Endometriosis Research and Treatment
Health Sciences › Medicine › Public Health, Environmental and Occupational Health › Menstrual Health and Disorders
Health Sciences › Health Professions › Physical Therapy, Sports Therapy and Rehabilitation › Musculoskeletal pain and rehabilitation
Keywords: chronic pelvic pain, prevalence, health-related quality of life, labor productivity, health care utilization, endometriosis, health care costs, women's health, lost workdays
MeSH terms: Adolescent, Adult, Chronic Disease, Endometriosis, Female, Health Services Needs and Demand, Humans, Middle Aged, Quality of Life, Socioeconomic Factors, United States, Prevalence, Cost of Illness, Pelvic Pain

About these checks

Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.

Statistics and arithmetic are recomputed, not judged.

Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.

What counts as a claim ›How we measure confidence ›How we check this ›

Are you an author, or do you see a problem with this page? Request a review

Chronic Pelvic Pain: Prevalence, Health-Related Quality of Life, and Economic Correlates

Abstract

Overview

Integrity signals

Verification

Claims the paper makes

Claims other papers make about this one

Citations

Cites

Cited by

Related

Metadata

Record

About these checks