The DOI matches its Crossref record.
Interleukin-8 Synthesis and the Onset of Labor
Abstract
OBJECTIVE: To examine the role of cytokines in cervical dilation. METHODS: In 55 patients undergoing cesarean delivery, we took samples from the lower uterine segment, the decidua, and the membranes. We determined the concentrations of interleukin (IL)-2, IL-8, tumor necrosis factor-alpha, matrix metalloproteinase (MMP)-8, and MMP-9 in the different tissues. RESULTS: Depending on the state of labor, we observed a significant increase (P < .001) in IL-8 concentrations in the lower uterine segment. The leukocyte enzymes MMP-8 and MMP-9 were highly significantly correlated with the IL-8 concentrations. CONCLUSION: Interleukin-8 is critically involved in the process of parturition in humans. Interleukin-8 concentrations in the myometrium, decidua, and membranes correlated strongly with the observed MMP-8 and MMP-9 concentrations.
Overview
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Integrity signals
Registry
Cites
Statistics
Verification
Claims the paper makes
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Self-check
Percentages, sums and reported differences re-computed from the paper’s own numbers.
The self-check needs the paper’s full text.
Citations
Cited by
Cytokines, Prostaglandins and Parturition—A Review
Keelan, J. A., Blumenstein, M., Helliwell, R. J. A., Sato, T. A., Marvin, K. W., & Mitchell, M. D. (2003) · Placenta · doi:10.1053/plac.2002.0948 · Cited by 606
Elevated Maternal Interleukin-8 Levels and Risk of Schizophrenia in Adult Offspring
Brown, A. S., Hooton, J., Schaefer, C. A., Zhang, H., Petkova, E., Babulas, V., Perrin, M., Gorman, J. M., & Susser, E. S. (2004) · American Journal of Psychiatry · doi:10.1176/appi.ajp.161.5.889 · Cited by 489
Young, A., Thomson, A. J., Ledingham, M., Jordan, F., Greer, I. A., & Norman, J. E. (2002) · Biology of Reproduction · doi:10.1095/biolreprod66.2.445 · Cited by 361
Cervical remodeling during pregnancy and parturition
Timmons, B., Akins, M., & Mahendroo, M. (2010) · Trends in Endocrinology & Metabolism · doi:10.1016/j.tem.2010.01.011 · Cited by 360
Bowen, J. M., Chamley, L., Keelan, J. A., & Mitchell, M. D. (2002) · Placenta · doi:10.1053/plac.2001.0782 · Cited by 337
Metadata
- Authors
- Osmers, R.
- Venue
- Obstetrics & Gynecology
- Published
- 1995-08
- Volume
- 86
- Issue
- 2
- Pages
- 223-229
- ISSN
- 0029-7844 (ISSN-L)
- OpenAlex
- W2051822184
- Cited by
- 224
- References
- 0
- FWCI
- 9.93
- Type
- journal article
- Language
- en
- Open access
- closed
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
Are you an author, or do you see a problem with this page? Request a review
How to cite
Cite CoChat for the checks on this page, and the paper for its own findings.
- This page
- CoChat. (2026). Citation check: Interleukin-8 Synthesis and the Onset of Labor. https://app.cochat.ai/papers/10.1016/0029-7844(95)93704-4
- The paper
- Osmers, R. (1995). Interleukin-8 Synthesis and the Onset of Labor. Obstetrics & Gynecology. https://doi.org/10.1016/0029-7844(95)93704-4
Data sources
Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
