The electroretinogram: Its components and their origins
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The lowered a- and b-wave amplitudes in the AAV9-EGFP subretinal group could implicate both rod- and cone-focused pathway dependency being compromised in this group.
“This could implicate both rod- and cone-focused pathway dependency being compromised in this group because the a-wave originates from the photoreceptor level, and the b-wave is mainly composed of bipolar cell response (Brown, 1968; Stockton and Slaughter, 1989; Pugh et al., 1998).”
From AAV2 and AAV9 tropism and transgene expression in the mouse eye and major tissues after intravitreal and subretinal delivery (2023) · cites this paper as Brown, 1968
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Retinopathy induced in mice by targeted disruption of the rhodopsin gene
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B-wave of the electroretinogram. A reflection of ON bipolar cell activity
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Visual function in regenerating teleost retina following cytotoxic lesioning
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“This could implicate both rod-and cone-focused pathway dependency being compromised in this group because the a-wave originates from the photoreceptor level, and the b-wave is mainly composed of bipolar cell response (Brown, 1968; Stockton and Slaughter, 1989; Pugh et al., 1998).”
- Authors
- Brown, K. T.
- Affiliations
- University of California, San Francisco (US)
- Corresponding author
- Brown, Kenneth T.
- Venue
- Vision Research
- Publisher
- Elsevier BV
- Published
- 1968-06
- Volume
- 8
- Issue
- 6
- Pages
- 633-IN6
- ISSN
- 0042-6989 (ISSN-L)
- OpenAlex
- W1977423618
- Cited by
- 558
- References
- 81
- Citations by year
- 2026: 4 · 2025: 8 · 2024: 9 · 2023: 8 · 2022: 8 · 2021: 8 · 2020: 12 · 2019: 12 · 2018: 3 · 2017: 10 · 2016: 4 · 2015: 4 · 2014: 9 · 2013: 12 · 2012: 6
- FWCI
- 2.52
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- Vision Research (publishedVersion)
- PubMed (publishedVersion)
- Topics
- Life Sciences › Biochemistry, Genetics and Molecular Biology › Molecular Biology › Retinal Development and Disorders
- Health Sciences › Medicine › Ophthalmology › Retinal Diseases and Treatments
- Life Sciences › Neuroscience › Cognitive Neuroscience › Visual perception and processing mechanisms
- Keywords
- electroretinogram, retinal potentials, receptor potential, b-wave, c-wave, pigment epithelium, off-response, inner nuclear layer, retinal cell types, retinal function, mammalian retina, retinal degeneration
- MeSH terms
- Adaptation, Ocular, Animals, Haplorhini, Anura, Cats, Electroretinography, Evoked Potentials, Macula Lutea, Photoreceptor Cells, Rabbits, Retina, Retinal Degeneration, Sciuridae
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