The DOI matches its Crossref record.
More than three different cone pigments among people with normal color vision
Abstract
A fundamental feature of normal color vision is that red and green lights can be mixed to appear identical with a monochromatic yellow light. Another characteristic of normal color vision is that people often disagree on the amounts of red and green needed in the mixture to exactly match the yellow. Comparison of such color vision differences with photopigment gene differences reveals that a serine/alanine polymorphism at amino acid position 180 of X-encoded pigments can account for this type of color vision variation. This amino acid change shifts the spectrum of the pigment produced by about 6 nm, a value that would predict a larger minimum color vision difference between individuals than is actually observed. This discrepancy can be explained if, counter to the Young-Helmholtz theory as the explanation of trichromacy, many people with normal color vision have more than three spectrally different cone pigments.
Overview
Integrity signals
Registry
Cites
Statistics
Verification
Claims the paper makes
Claims other papers make about this one
Each is checked against this paper’s own text: does it say what the citing paper says it does?
In the citing paper
“it is principally the result of the S/A difference at position 180 of the L pigment”
From The genetics of normal and defective color vision (2011) · cites this paper as Neitz, Neitz & Jacobs, 1993
Citations
Cites
No references could be resolved yet.
Research works printed but not linked: 21
- Alpern, 1977, The red and green cone visual pigments of deuteranomalous trichromacy, Journal of Physiology, London, 266, 647, 10.1113/jphysiol.1977.sp011786 · DOI
- Eisner, 1981, Flicker photometric study of chromatic adaptation: Selective suppression of cone inputs by colored backgrounds, Journal of the Optical Society of America, 71, 705, 10.1364/JOSA.71.000705 · DOI
- Elsner, 1987, Classes of color normal observers, Journal of the Optical Society of America, A4, P123
- 1987, Frontiers of visual science: Proceedings of the 1985 symposium
- Jordan, 1988, Two kinds of men?, Investigative Ophthalmology and Visual Science (Suppl.), 29, 164
- Lindsey, 1992, Individual differences in Rayleigh matches are related to differences in L cone pigment structure, Advances in Color Vision: Journal of the Optical Society of America, Technical Digest Series, 4, 17
- Lutze, 1990, Genetic studies of variation in Rayleigh and photometric matches in normal trichromats, Vision Research, 30, 149, 10.1016/0042-6989(90)90134-7 · DOI
- Nagy, 1985, Cone mechanisms underlying the color discrimination of deutan color deficients, Vision Research, 25, 661, 10.1016/0042-6989(85)90172-5 · DOI
- Nagy, 1981, Four cone pigments in women heterozygous for color deficiency, Journal of the Optical Society of America, 71, 719, 10.1364/JOSA.71.000719 · DOI · Paper page
- Nathans, 1986, Molecular genetics of human color vision: The genes encoding blue, green and red pigments, Science, New York, 232, 193, 10.1126/science.2937147 · DOI
- Neitz, 1986, Polymorphism of the long-wavelength cone in normal human color vision, Nature, London, 323, 623, 10.1038/323623a0 · DOI · Paper page
- Neitz, 1990, Polymorphism in normal human color vision and its mechanism, Vision Research, 30, 620, 10.1016/0042-6989(90)90073-T · DOI
- Neitz, 1991, Spectral tuning of pigments underlying red-green color vision, Science, New York, 252, 971, 10.1126/science.1903559 · DOI · Paper page
- Neitz, 1991, Genes and encoded M-cone pigments from two types of protanope, Journal of the Optical Society of America, Technical Digest Series, 17, 23
- Neitz, 1991, Matches from normal trichromatic males suggest that some eyes contain more than three cone types, Investigative Ophthalmology and Visual Science (Suppl.), 32, 1092
- Pokorny, 1973, Derivation of the photopigment absorption spectra in anomalous trichromats, Journal of the Optical Society of America, 63, 232, 10.1364/JOSA.63.000232 · DOI
- Poncz, 1983, Construction of human gene libraries from small amounts of peripheral blood, Hemoglobin, 6, 27, 10.3109/03630268208996930 · DOI
- Shevell, 1992, Dual Rayleigh-like color matches sensitive to individual differences in cone photopigments, Advances in Color Vision: Journal of the Optical Society of America, Technical Digest Series, 4, 20
- Waaler, 1967, Heredity of two types of normal colour vision, Nature, London, 215, 406, 10.1038/215406a0 · DOI
- Webster, 1988, Factors underlying individual differences in the color matches of normal observers, Journal of the Optical Society of America, A5, 1722, 10.1364/JOSAA.5.001722 · DOI
- Young, 1802, On the theory of light and colours, Philosophical Transactions of the Royal Society of London, 92, 12, 10.1098/rstl.1802.0004 · DOI
Cited by
Sorted by citations
The genetics of normal and defective color vision
Neitz, J., & Neitz, M. (2011) · Vision Research · doi:10.1016/j.visres.2010.12.002 · Cited by 377
Self-citation
Metadata
- Authors
- Neitz, J., Neitz, M., & Jacobs, G. H.
- Venue
- Vision Research
- Publisher
- Elsevier BV
- Published
- 1993-01
- Volume
- 33
- Issue
- 1
- Pages
- 117-122
- ISSN
- 0042-6989
- Cited by
- 77
- References
- 0
- Language
- en
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
Are you an author, or do you see a problem with this page? Request a review
How to cite
Cite CoChat for the checks on this page, and the paper for its own findings.
- This page
- CoChat. (2026). Citation check: More than three different cone pigments among people with normal color vision. https://app.cochat.ai/papers/10.1016/0042-6989(93)90064-4
- The paper
- Neitz, J., Neitz, M., & Jacobs, G. H. (1993). More than three different cone pigments among people with normal color vision. Vision Research. https://doi.org/10.1016/0042-6989(93)90064-4