Genetic control of morphogenetic and biochemical differentiation: Lethal albino deletions in the mouse

Why genes in pieces?

Gilbert, W. (1978) · Nature · doi:10.1038/271501a0 · Cited by 2,300 · see citing works

The Chemical Basis of Heredity

Newcombe, H. B., McElroy, W. D., & Glass, B. (1957) · AIBS Bulletin · doi:10.2307/1292482 · Cited by 1,041 · see citing works

Hysterectomy rates in the United States 1990–1997

Farquhar, C. M. (2002) · Obstetrics and Gynecology · doi:10.1016/s0029-7844(01)01723-9 · Cited by 645 · see citing works

Etiology and pathogenesis of uterine leiomyomas: a review.

Flake, G. P., Andersen, J., & Dixon, D. (2002) · Environmental Health Perspectives · doi:10.1289/ehp.5787 · Cited by 584 · see citing works

Control of Specific Gene Expression in Higher Organisms

Tomkins, G. M., GELEHRTER, T. D., Granner, D. K., Martin, D. W., Samuels, H. H., & Thompson, E. B. (1969) · Science · doi:10.1126/science.166.3912.1474 · Cited by 543 · see citing works

Is Estradiol a Genotoxic Mutagenic Carcinogen?1

Liehr, J. G. (2000) · Endocrine Reviews · doi:10.1210/edrv.21.1.0386 · Cited by 486 · see citing works

General Model for the Chromosomes of Higher Organisms

Crick, F. H. C. (1971) · Nature · doi:10.1038/234025a0 · Cited by 422 · see citing works

Unravelling the activation mechanisms of protein kinase B/Akt

Scheid, M. P., & Woodgett, J. R. (2003) · FEBS Letters · doi:10.1016/s0014-5793(03)00562-3 · Cited by 389 · see citing works

Quinacrine, A Chromosome Stain Specific for Deoxyadenylate-Deoxythymidylate-Rich Regions in DNA

Weisblum, B., & Haseth, P. L. D. (1972) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.69.3.629 · Cited by 299 · see citing works

DIFFERENTIATION OF ENDOPLASMIC RETICULUM IN HEPATOCYTES

Leskes, A., Siekevitz, P., & Palade, G. E. (1971) · The Journal of Cell Biology · doi:10.1083/jcb.49.2.264 · Cited by 276 · see citing works

The elementary units of heredity.

Benzer, S. (1956) · Cited by 187 · see citing works

Synthesis, Antitubulin and Antimitotic Activity, and Cytotoxicity of Analogs of 2-Methoxyestradiol, an Endogenous Mammalian Metabolite of Estradiol That Inhibits Tubulin Polymerization by Binding to the Colchicine Binding Site

Cushman, M., He, H.-M., Katzenellenbogen, J. A., Lin, C. M., & Hamel, E. (1995) · Journal of Medicinal Chemistry · doi:10.1021/jm00012a003 · Cited by 183 · see citing works

Epidemiologic Contributions to Understanding the Etiology of Uterine Leiomyomata

Schwartz, S. M., Marshall, L. M., & Baird, D. D. (2000) · Environmental Health Perspectives · doi:10.1289/ehp.00108s5821 · Cited by 181 · see citing works

Oestrogen receptor-alpha gene polymorphism is associated with endometriosis, adenomyosis and leiomyomata

Kitawaki, J., Obayashi, H., Ishihara, H., Koshiba, H., Kusuki, I., Kado, N., Tsukamoto, K., Hasegawa, G., Nakamura, N., & Honjo, H. (2001) · Human Reproduction · doi:10.1093/humrep/16.1.51 · Cited by 160 · see citing works

Abnormal Spermiogenesis in Quaking, a Myelin-Deficient Mutant Mouse1

Bennett, W. I., Gall, A. M., Southard, J. L., & Sidman, R. L. (1971) · Biology of Reproduction · doi:10.1093/biolreprod/5.1.30 · Cited by 140 · see citing works

The molecular genetics of mammalian glucuronidase

Paigen, K., Swank, R. T., Tomino, S., & Ganschow, R. E. (1975) · Journal of Cellular Physiology · doi:10.1002/jcp.1040850406 · Cited by 132 · see citing works

X-Autosome Translocations in The Mouse: Total Inactivation Versus Partial Inactivation Of The X Chromosome

Eicher, E. M. (1970) · Advances in genetics · doi:10.1016/s0065-2660(08)60074-7 · Cited by 115 · see citing works

Lethal Genes and Analysis of Differentiation

Gluecksohn‐Waelsch, S. (1963) · Science · doi:10.1126/science.142.3597.1269 · Cited by 105 · see citing works

X‐Linked testicular feminization in the mouse as a non‐inducible regulatory mutation of the Jacob‐Monod type

Ohno, S., & Lyon, M. F. (1970) · Clinical Genetics · doi:10.1111/j.1399-0004.1970.tb01627.x · Cited by 101 · see citing works

Activation of production of mouse liver enzymes in rat hepatoma-mouse lymphoid cell hybrids

Brown, J. E., & Weiss, M. C. (1975) · Cell · doi:10.1016/0092-8674(75)90037-9 · Cited by 99 · see citing works

Abnormal gene expression in uterine leiomyomas

Andersen, J. (1995) · Journal of the Society for Gynecologic Investigation · doi:10.1016/1071-5576(95)00021-6 · Cited by 89 · see citing works

Glucose-6-phosphatase deficiency caused by radiation-induced alleles at the albino locus in the mouse.

Erickson, R. P., Gluecksohn‐Waelsch, S., & Cori, C. F. (1968) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.59.2.437 · Cited by 64 · see citing works

Estrogen receptor α-351 XbaI*G and -397 PvuII*C-related genotypes and alleles are associated with higher susceptibilities of endometriosis and leiomyoma

Hsieh, Y.-Y., Wang, Y.-K., Chang, C.-C., & Lin, C. (2006) · Molecular Human Reproduction · doi:10.1093/molehr/gal099 · Cited by 63 · see citing works

Complementation Studies of Lethal Alleles in the Mouse Causing Deficiencies of Glucose-6-Phosphatase, Tyrosine Aminotransferase, and Serine Dehydratase

Gluecksohn‐Waelsch, S., Schiffman, M. B., Thorndike, J., & Cori, C. F. (1974) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.71.3.825 · Cited by 52 · see citing works

ULTRASTRUCTURAL BASIS OF BIOCHEMICAL EFFECTS IN A SERIES OF LETHAL ALLELES IN THE MOUSE

Trigg, M. J., & Gluecksohn‐Waelsch, S. (1973) · The Journal of Cell Biology · doi:10.1083/jcb.58.3.549 · Cited by 50 · see citing works

Polymorphisms in ER-alpha gene interact with estrogen receptor status in breast cancer survival.

Boyapati, S. M., Shu, X., Ruan, Z.-X., Cai, Q., Smith, J. R., Wen, W., Gao, Y., & Zheng, W. (2005) · PubMed · Cited by 45 · see citing works

Multiple biochemical effects of a series of X-ray induced mutations at the albino locus in the mouse

Thorndike, J., Trigg, M. J., Stockert, R. J., Gluecksohn‐Waelsch, S., & Cori, C. F. (1973) · Biochemical Genetics · doi:10.1007/bf00485588 · Cited by 43 · see citing works

Estrogen receptor α dinucleotide repeat and cytochrome P450c17α gene polymorphisms are associated with susceptibility to endometriosis

Hsieh, Y., Chang, C.-C., Tsai, F., Lin, C., & Tsai, C. (2005) · Fertility and Sterility · doi:10.1016/j.fertnstert.2004.07.977 · Cited by 42 · see citing works

Fertility studies of complementing genotypes at the albino locus of the mouse

Lewis, S. E., Turchin, H. A., & Wójtowicz, T. (1978) · Reproduction · doi:10.1530/jrf.0.0530197 · Cited by 33 · see citing works

Developmental analysis of lethal effects of homozygosity for the C25H deletion in the mouse

Lewis, S. E. (1978) · Developmental Biology · doi:10.1016/0012-1606(78)90052-0 · Cited by 31 · see citing works

Demonstration in mouse of X-ray induced deletions for a known enzyme structural locus

Erickson, R. P., Eicher, E. M., & Gluecksohn‐Waelsch, S. (1974) · Nature · doi:10.1038/248416a0 · Cited by 30 · see citing works

The developmental analysis of an embryonic lethal (c6H) in the mouse

Lewis, S. E., Turchin, H. A., & Gluecksohn‐Waelsch, S. (1976) · Development · doi:10.1242/dev.36.2.363 · Cited by 29 · see citing works

Linkage of the locus for serum albumin in the house mouse, Mus musculus

Nichols, E. A., Ruddle, F. H., & Petras, M. L. (1975) · Biochemical Genetics · doi:10.1007/bf00484914 · Cited by 28 · see citing works

Is genetic polymorphism of ER-α, CYP1A1, and CYP1B1 a risk factor for uterine leiomyoma?

El-Shennawy, G., Elbialy, A. A., Isamil, A. E., & Behery, M. M. E. (2010) · Archives of Gynecology and Obstetrics · doi:10.1007/s00404-010-1550-x · Cited by 28 · see citing works

HLA: a super supergene.

Bodmer, W. F. (1978) · PubMed · Cited by 27 · see citing works

CYTOLOGICAL DETECTION OF THE c 25H DELETION INVOLVING THE ALBINO (c) LOCUS ON CHROMOSOME 7 IN THE MOUSE

Miller, D. A., Dev, V. G., Tantravahi, R. V., Miller, O. J., Schiffman, M. B., Yates, R. A., & Gluecksohn‐Waelsch, S. (1974) · Genetics · doi:10.1093/genetics/78.3.905 · Cited by 26 · see citing works

Glucose 6-phosphatase deficiency: Mechanisms of genetic control and biochemistry

Gluecksohn‐Waelsch, S., & Cori, C. F. (1970) · Biochemical Genetics · doi:10.1007/bf00484030 · Cited by 24 · see citing works

Genetically determined abnormalities of microsomal enzymes in liver of mutant newborn mice

Thaler, M., Erickson, R. P., & Pelger, A. L. (1976) · Biochemical and Biophysical Research Communications · doi:10.1016/s0006-291x(76)80148-9 · Cited by 20 · see citing works

Premature development of ligandin (GSH transferase B) in mice with an inherited defect in endoplasmic reticulum-golgi structure and function

Gatmaitan, Z., Lewis, S. E., Turchin, H. A., & Arias, I. M. (1977) · Biochemical and Biophysical Research Communications · doi:10.1016/0006-291x(77)91047-6 · Cited by 19 · see citing works

Effect of gene dosage on expression of mitochondrial malic enzyme activity in the mouse

Bernstine, E. G., Russell, L. B., & CAIN, C. S. (1978) · Nature · doi:10.1038/271748a0 · Cited by 18 · see citing works

Cytological observations of deletions in pachytene stages of oogenesis and spermatogenesis in the mouse

JAGIELLO, G. M., Fang, J., Turchin, H. A., Lewis, S. E., & Gluecksohn‐Waelsch, S. (1976) · Chromosoma · doi:10.1007/bf00292845 · Cited by 16 · see citing works

Gene dosage in a deletion for a nuclear-coded, mitochondrial enzyme

Diamond, R., & Erickson, R. P. (1974) · Nature · doi:10.1038/248418a0 · Cited by 14 · see citing works

Glutamine synthetase in newborn mice homozygous for lethal albino alleles

Gluecksohn‐Waelsch, S., Schiffman, M. B., & Moscona, M. H. (1975) · Developmental Biology · doi:10.1016/0012-1606(75)90075-5 · Cited by 13 · see citing works

Ultrastructural studies of lethal c25H/c25H mouse embryos

Nadijcka, M. D., Hillman, N. W., & Gluecksohn‐Waelsch, S. (1979) · Development · doi:10.1242/dev.52.1.1 · Cited by 12 · see citing works

Polymorphisms of CYP17A1, CYP19, and androgen in Brazilian women with uterine leiomyomas

Rosa, F. E., Canevari, R. D. A., Ambrosio, E. P., Cirilo, P. D. R., Pontes, A., Rainho, C. A., & Rogatto, S. R. (2008) · Clinical Chemistry and Laboratory Medicine (CCLM) · doi:10.1515/cclm.2008.172 · Cited by 12 · see citing works

Chemical and immunological studies of liver microsomes from mouse mutants with ultrastructurally abnormal hepatic endoplasmic reticulum

Erickson, R. P., Siekevitz, P., Jacobs, K. A., & Gluecksohn‐Waelsch, S. (1974) · Biochemical Genetics · doi:10.1007/bf00487530 · Cited by 10 · see citing works

Absence of mitochondrial malic enzyme in mice carrying two complementing lethal albino alleles

Eicher, E. M., Lewis, S. E., Turchin, H. A., & Gluecksohn‐Waelsch, S. (1978) · Genetics Research · doi:10.1017/s0016672300018462 · Cited by 8 · see citing works

The mouse chromosome map.

Miller, O. J., & Miller, D. A. (1975) · PubMed · Cited by 3 · see citing works

Serum protein synthesis in mutant mice with abnormal hepatic endoplasmic reticulum.

Rp, E., Pickart, L., & Mm, T. (1976) · PubMed · Cited by 3 · see citing works

Akt, FoxO and regulation of apoptosis

Zhang, X., Tang, N., Hadden, T. J., & Rishi, A. K. (2011) · Biochimica et Biophysica Acta (BBA) - Molecular Cell Research · doi:10.1016/j.bbamcr.2011.03.010 · Cited by 1,112 · see citing works

Role of the aromatic hydrocarbon receptor and [Ah] gene battery in the oxidative stress response, cell cycle control, and apoptosis

Nebert, D. W., Roe, A. L., Dieter, M. Z., Solis, W. A., Yang, Y., & Dalton, T. P. (2000) · Biochemical Pharmacology · doi:10.1016/s0006-2952(99)00310-x · Cited by 997 · see citing works

Cooperativity of glucocorticoid response elements located far upstream of the tyrosine aminotransferase gene

Jantzen, H., Strähle, U., Gloss, B. R., Stewart, F., Schmid, W., Boshart, M., Miksicek, R. J., & Schütz, G. (1987) · Cell · doi:10.1016/0092-8674(87)90752-5 · Cited by 724 · see citing works

Mammalian Genes Coordinately Regulated by Growth Arrest Signals and DNA-Damaging Agents

Fornace, A. J., Nebert, D. W., Hollander, M. C., Luethy, J. D., Papathanasiou, M., Fargnoli, J., & Holbrook, N. J. (1989) · Molecular and Cellular Biology · doi:10.1128/mcb.9.10.4196 · Cited by 705 · see citing works

Hepatocytes corrected by gene therapy are selected in vivo in a murine model of hereditary tyrosinaemia type I

Overturf, K., Al-Dhalimy, M., Tanguay, R., Brantly, M., Ou, C.-N., Finegold, M., & Grompe, M. (1996) · Nature Genetics · doi:10.1038/ng0396-266 · Cited by 549 · see citing works

The glucose-6-phosphatase system

SCHAFTINGEN, E. V., & Gerin, I. (2002) · Biochemical Journal · doi:10.1042/0264-6021:3620513 · Cited by 495 · see citing works

Minor Xp21 chromosome deletion in a male associated with expression of Duchenne muscular dystrophy, chronic granulomatous disease, retinitis pigmentosa, and McLeod syndrome.

Francke, U., Ochs, H. D., de Martinville, B., Giacalone, J. C., Lindgren, Distèche, C. M., Ra, P., Hofker, M. H., van Ommen, G. B., & Pearson, P. L. (1985) · PubMed · Cited by 453 · see citing works

Isolation and sequence of a cDNA clone for human tyrosinase that maps at the mouse c-albino locus.

Kwon, B. S., Haq, A. K., Pomerantz, S. H., & Halaban, R. (1987) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.84.21.7473 · Cited by 438 · see citing works

Role of the Ah Receptor and the Dioxin‐Inducible [Ah] Gene Battery in Toxicity, Cancer, and Signal Transductiona

Nebert, D. W., Puga, A., & Vasiliou, V. (1993) · Annals of the New York Academy of Sciences · doi:10.1111/j.1749-6632.1993.tb35928.x · Cited by 419 · see citing works

Embryonic lethal mutation in mice induced by retrovirus insertion into the α1(I) collagen gene

Schnieke, A., Harbers, K., & Jaenisch, R. (1983) · Nature · doi:10.1038/304315a0 · Cited by 416 · see citing works

Mutations in the Glucose-6-Phosphatase Gene that Cause Glycogen Storage Disease Type 1a

Lei, K.-J., Shelly, L. L., Pan, C., Sidbury, J. B., & CHOU, J. Y. (1993) · Science · doi:10.1126/science.8211187 · Cited by 377 · see citing works

Loss of fumarylacetoacetate hydrolase is responsible for the neonatal hepatic dysfunction phenotype of lethal albino mice

Grompe, M., al-Dhalimy, M., Finegold, M., Ou, C. N., Burlingame, T., Kennaway, N. G., & Soriano, P. (1993) · Genes & Development · doi:10.1101/gad.7.12a.2298 · Cited by 355 · see citing works

Pharmacological correction of neonatal lethal hepatic dysfunction in a murine model of hereditary tyrosinaemia type I

Grompe, M., Lindstedt, S., Al-Dhalimy, M., Kennaway, N. G., Papaconstantinou, J., Torres-Ramos, C. A., Ou, C.-N., & Finegold, M. (1995) · Nature Genetics · doi:10.1038/ng0895-453 · Cited by 312 · see citing works

Functional analysis of alternatively spliced tyrosinase gene transcripts.

Müller, G., Ruppert, S., Schmid, E., & Schütz, G. (1988) · The EMBO Journal · doi:10.1002/j.1460-2075.1988.tb03126.x · Cited by 271 · see citing works

Is CCAAT/enhancer-binding protein a central regulator of energy metabolism?Preprint

McKnight, S. L., Lane, M. D., & Gluecksohn‐Waelsch, S. (1989) · Genes & Development · doi:10.1101/gad.3.12b.2021 · Cited by 251 · see citing works

Tyrosinases from two different loci are expressed by normal and by transformed melanocytes.

Jiménez, M. I., Tsukamoto, K., & Hearing, V. J. (1991) · Journal of Biological Chemistry · doi:10.1016/s0021-9258(17)35295-x · Cited by 231 · see citing works

Insertion of retrovirus into the first intron of alpha 1(I) collagen gene to embryonic lethal mutation in mice.

Harbers, K., Kuehn, M. R., Delius, H., & Jaenisch, R. (1984) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.81.5.1504 · Cited by 225 · see citing works

Tyrosinemia: A Review

Russo, P., Mitchell, G. A., & Tanguay, R. M. (2001) · Pediatric and Developmental Pathology · doi:10.1007/s100240010146 · Cited by 222 · see citing works

Cellular Responses to Oxidative Stress: The [Ah] Gene Battery As a Paradigm

Nebert, D. W., Petersen, D. D., & Fornace, A. J. (1990) · Environmental Health Perspectives · doi:10.1289/ehp.908813 · Cited by 208 · see citing works

Regulation of the C/EBP-Related Gene gadd153 by Glucose Deprivation

Carlson, S. G., Fawcett, T. W., Bartlett, J. D., Bernier, M., & Holbrook, N. J. (1993) · Molecular and Cellular Biology · doi:10.1128/mcb.13.8.4736 · Cited by 188 · see citing works

Carbohydrate Metabolism and Its Diseases

Kaneko, J. J. (1997) · Elsevier eBooks · doi:10.1016/b978-012396305-5/50004-x · Cited by 181 · see citing works

Multiple transcripts of the mouse tyrosinase gene are generated by alternative splicing.

Ruppert, S., Müller, G., Kwon, B. S., & Schütz, G. (1988) · The EMBO Journal · doi:10.1002/j.1460-2075.1988.tb03125.x · Cited by 181 · see citing works

Human tyrosinase gene, mapped to chromosome 11 (q14 → q21), defines second region of homology with mouse chromosome 7

Barton, D. E., Kwon, B. S., & Francke, U. (1988) · Genomics · doi:10.1016/0888-7543(88)90153-x · Cited by 169 · see citing works

The pathophysiology and treatment of hereditary tyrosinemia type 1

Grompe, M. (2001) · Seminars in Liver Disease · doi:10.1055/s-2001-19035 · Cited by 167 · see citing works

FREQUENCY OF γ-RAY INDUCED SPECIFIC LOCUS AND RECESSIVE LETHAL MUTATIONS IN MATURE GERM CELLS OF THE ZEBRAFISH, BRACHYDANIO RERIO

Chakrabarti, S., Streisinger, G., Singer, F. D., & Walker, C. (1983) · Genetics · doi:10.1093/genetics/103.1.109 · Cited by 158 · see citing works

Isolation of the gene for murine glucose-6-phosphatase, the enzyme deficient in glycogen storage disease type 1A.

Shelly, L. L., Lei, K. J., Pan, C. J., Sakata, S., Ruppert, S., Schütz, G., & CHOU, J. Y. (1993) · Journal of Biological Chemistry · doi:10.1016/s0021-9258(20)80563-8 · Cited by 144 · see citing works

Two genetically defined trans-acting loci coordinately regulate overlapping sets of liver-specific genes

Ruppert, S., Boshart, M., Bosch, F. X., Schmid, W., Fournier, R. E. K., & Schütz, G. (1990) · Cell · doi:10.1016/0092-8674(90)90200-x · Cited by 139 · see citing works

Tissue‐specific DNaseI hypersensitive sites in the 5′‐flanking sequences of the tryptophan oxygenase and the tyrosine aminotransferase genes.

Becker, P. B., Renkawitz, R., & Schütz, G. (1984) · The EMBO Journal · doi:10.1002/j.1460-2075.1984.tb02084.x · Cited by 134 · see citing works

Transcription activation of the tyrosine aminotransferase gene by glucocorticoids and cAMP in primary hepatocytes

SCHMID, E., Schmid, W., JANTZEN, M., Mayer, D., Jastorff, B., & SCHUTZ, G. (1987) · European Journal of Biochemistry · doi:10.1111/j.1432-1033.1987.tb11467.x · Cited by 129 · see citing works

Inappropriate use of albino animals as models in research

Creel, D. J. (1980) · Pharmacology Biochemistry and Behavior · doi:10.1016/0091-3057(80)90461-x · Cited by 127 · see citing works

Isolation and characterization of the rat tyrosine aminotransferase gene.

Shinomiya, T., Scherer, G., Schmid, W., Zentgraf, H., & Schütz, G. (1984) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.81.5.1346 · Cited by 123 · see citing works

Transcriptional activation of the rat liver tyrosine aminotransferase gene by cAMP.

Hashimoto, S., Schmid, W., & Schütz, G. (1984) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.81.21.6637 · Cited by 122 · see citing works

A strategy for fine-structure functional analysis of a 6- to 11-centimorgan region of mouse chromosome 7 by high-efficiency mutagenesis.

Rinchik, E. M., Carpenter, D. A., & Selby, P. B. (1990) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.87.3.896 · Cited by 118 · see citing works

A cell‐specific enhancer far upstream of the mouse tyrosinase gene confers high level and copy number‐related expression in transgenic mice.

Ganss, R., Montoliu, L., Monaghan, A. P., & Schütz, G. (1994) · The EMBO Journal · doi:10.1002/j.1460-2075.1994.tb06607.x · Cited by 112 · see citing works

Transcriptional regulation of genes for ornithine cycle enzymes

Takiguchi, M., & Mori, M. (1995) · Biochemical Journal · doi:10.1042/bj3120649 · Cited by 111 · see citing works

A genetically definedtrans‐acting locus regulatesS‐locus function inBrassica

Nasrallah, M. E., Kandasamy, M. K., & Nasrallah, J. B. (1992) · The Plant Journal · doi:10.1111/j.1365-313x.1992.00497.x · Cited by 108 · see citing works

Isolation of cDNA clones coding for rat tyrosine aminotransferase.

Scherer, G., Schmid, W., STRANGE, C. M., Röwekamp, W. G., & Schütz, G. (1982) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.79.23.7205 · Cited by 106 · see citing works

Early postimplantation embryo lethality due to DNA rearrangements in a transgenic mouse strain.

Covarrubias, L., Nishida, Y., & Mintz, B. (1986) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.83.16.6020 · Cited by 104 · see citing works

N-Ethyl-N-Nitrosourea Mutagenesis of a 6- to 11-cM Subregion of the Fah–Hbb Interval of Mouse Chromosome 7: Completed Testing of 4557 Gametes and Deletion Mapping and Complementation Analysis of 31 Mutations

Rinchik, E. M., & Carpenter, D. A. (1999) · Genetics · doi:10.1093/genetics/152.1.373 · Cited by 101 · see citing works

The Essentiality of Reporting Hardy-Weinberg Equilibrium Calculations in Population-Based Genetic Association Studies.

Namipashaki, A., Razaghi‐Moghadam, Z., & Ansari‐Pour, N. (2015) · PubMed Central · doi:10.22074/cellj.2016.3711 · Cited by 103 · see citing works

[16] Cloning regulated yeast genes from a pool of lacZ fusions

Ruby, S. W., Szostak, J. W., & Murray, A. W. (1983) · Methods in enzymology on CD-ROM/Methods in enzymology · doi:10.1016/0076-6879(83)01019-8 · Cited by 95 · see citing works

Deficiency of an enzyme of tyrosine metabolism underlies altered gene expression in newborn liver of lethal albino mice.

Ruppert, S., Kelsey, G., Schedl, A., Schmid, E., Thies, E., & Schütz, G. (1992) · Genes & Development · doi:10.1101/gad.6.8.1430 · Cited by 95 · see citing works

Genetic and molecular analysis of recessive alleles at the pink-eyed dilution (p) locus of the mouse.

Lyon, M. F., King, T. R., Gondo, Y., Gardner, J. M., Nakatsu, Y., Eicher, E. M., & Brilliant, M. H. (1992) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.89.15.6968 · Cited by 91 · see citing works

GENETIC CONTROL OF VERY EARLY MAMMALIAN DEVELOPMENT

Magnuson, T., & Epstein, C. J. (1981) · Biological reviews/Biological reviews of the Cambridge Philosophical Society · doi:10.1111/j.1469-185x.1981.tb00354.x · Cited by 86 · see citing works

Using Targeted Large Deletions and High-EfficiencyN-Ethyl-N-nitrosourea Mutagenesis for Functional Analyses of the Mammalian Genome

Justice, M. J., Zheng, B., Woychik, R. P., & Bradley, A. (1997) · Methods · doi:10.1006/meth.1997.0548 · Cited by 83 · see citing works

Hepatocyte injury in tyrosinemia type 1 is induced by fumarylacetoacetate and is inhibited by caspase inhibitors

Kubo, S., Sun, M., Miyahara, M., Umeyama, K., Urakami, K.-I., Yamamoto, T., Jakobs, C., Matsuda, I., & Endo, F. (1998) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.95.16.9552 · Cited by 77 · see citing works

Rescue of mice homozygous for lethal albino deletions: implications for an animal model for the human liver disease tyrosinemia type 1.

Kelsey, G., Ruppert, S., Beermann, F., Grund, C., Tanguay, R. M., & Schutz, G. (1993) · Genes & Development · doi:10.1101/gad.7.12a.2285 · Cited by 70 · see citing works

Point mutations in the murine fumarylacetoacetate hydrolase gene: Animal models for the human genetic disorder hereditary tyrosinemia type 1

Aponte, J. L., Sega, G. A., Hauser, L. J., Dhar, M. S., Withrow, C. M., Carpenter, D. A., Rinchik, E. M., Culiat, C. T., & Johnson, D. K. (2001) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.98.2.641 · Cited by 68 · see citing works

Regulation of the synthesis of tyrosine aminotransferase: the relationship to mRNATAT

Granner, D. K., & Hargrove, J. (1983) · Molecular and Cellular Biochemistry · doi:10.1007/bf00225249 · Cited by 65 · see citing works

Murine fumarylacetoacetate hydrolase (Fah) gene is disrupted by a neonatally lethal albino deletion that defines the hepatocyte-specific developmental regulation 1 (hsdr-1) locus.

Klebig, M. L., Russell, L. B., & Rinchik, E. M. (1992) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.89.4.1363 · Cited by 65 · see citing works

Tyrosine and its catabolites: from disease to cancer.

Tanguay, R. M., Jorquera, R., Poudrier, J., & St‐Louis, M. (1996) · Acta Biochimica Polonica · doi:10.18388/abp.1996_4530 · Cited by 64 · see citing works

Fumarylacetoacetate hydrolase deficient pigs are a novel large animal model of metabolic liver disease

Hickey, R., Mao, S. A., Glorioso, J. M., Lillegard, J. B., Fisher, J. E., Amiot, B. P., Rinaldo, P., Harding, C. O., Marler, R. J., Finegold, M. J., et al. (2014) · Stem Cell Research · doi:10.1016/j.scr.2014.05.003 · Cited by 63 · see citing works

Complete Rescue of Lethal Albino c Mice by Null Mutation of 4-Hydroxyphenylpyruvate Dioxygenase and Induction of Apoptosis of Hepatocytes in These Mice by in VivoRetrieval of the Tyrosine Catabolic Pathway

Endo, F., Kubo, S., Awata, H., Kiwaki, K., Katoh, H., Kanegae, Y., Saito, I., Miyazaki, J., Yamamoto, T., Jakobs, C., et al. (1997) · Journal of Biological Chemistry · doi:10.1074/jbc.272.39.24426 · Cited by 63 · see citing works

Carbohydrate Metabolism and Its Diseases

Kaneko, J. J. (2008) · Elsevier eBooks · doi:10.1016/b978-0-12-370491-7.00003-9 · Cited by 62 · see citing works

Late replication in an X-autosome translocation in the mouse: correlation with genetic inactivation and evidence for selective effects during embryogenesis.

Distèche, C. M., Eicher, E. M., & Latt, S. A. (1979) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.76.10.5234 · Cited by 61 · see citing works

Isolation, Chromosomal Mapping, and Expression of the Mouse Tyrosinase Gene

Kwon, B. S., Haq, A. K., Wakulchik, M., Kestler, D. P., Barton, D. E., Francke, U., Lamoreux, M. L., Whitney, J. B. I., & Halaban, R. (1989) · Journal of Investigative Dermatology · doi:10.1111/1523-1747.ep12319693 · Cited by 60 · see citing works

Interaction between the Ah receptor and proteins binding to the AP-1-like electrophile response element (EpRE) during murine phase II [Ah] battery gene expression

Vasiliou, V., Puga, A., Chang, C., Tabor, M. W., & Nebert, D. W. (1995) · Biochemical Pharmacology · doi:10.1016/0006-2952(95)02108-6 · Cited by 60 · see citing works

Chapter 11 Homeo Box Genes in Murine Development

Fienberg, A. A., Utset, M. F., Bogarad, L. D., Hart, C. P., Awgulewitsch, A., Ferguson‐Smith, A. C., Fainsod, A., Rabin, M., & Ruddle, F. H. (1987) · Current topics in developmental biology/Current Topics in Developmental Biology · doi:10.1016/s0070-2153(08)60627-4 · Cited by 58 · see citing works

Deletions near the albino locus on chromosome 7 of the mouse affect the level of tyrosine aminotransferase mRNA.

Schmid, W., Müller, G., Schütz, G., & Gluecksohn‐Waelsch, S. (1985) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.82.9.2866 · Cited by 57 · see citing works

Isolation of mouse X‐chromosome specific DNA from an X‐enriched lambda phage library derived from flow sorted chromosomes

Distèche, C. M., Kunkel, L. M., Lojewski, A., Orkin, S. H., Eisenhard, M., Sahar, E., Travis, B. M., & Latt, S. A. (1982) · Cytometry · doi:10.1002/cyto.990020503 · Cited by 56 · see citing works

Therapeutic trials in the murine model of hereditary tyrosinaemia type I: A progress report

Grompe, M., Overturf, K., Al-Dhalimy, M., & Finegold, M. J. (1998) · Journal of Inherited Metabolic Disease · doi:10.1023/a:1005462804271 · Cited by 54 · see citing works

Mouse Chromosome 7

Rinchik, E. M., Magnuson, T., Holdener‐Kenny, B., Kelsey, G., Bianchi, A. B., Conti, C. J., Chartier, F., Brown, K. A., Brown, S. D. M., & Peters, J. (1992) · Mammalian Genome · doi:10.1007/bf00648425 · Cited by 52 · see citing works

Asialoglycoprotein Receptor Expression in Murine Pregnancy and Development

Collins, J. C., Stockert, R. J., & Morell, A. G. (1984) · Hepatology · doi:10.1002/hep.1840040114 · Cited by 51 · see citing works

Trans regulation of the phosphoenolpyruvate carboxykinase (GTP) gene, identified by deletions in chromosome 7 of the mouse.

Loose, D. S., Shaw, P. A., Krauter, K. S., Robinson, C. A., Englard, S., Hanson, R. W., & Gluecksohn‐Waelsch, S. (1986) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.83.14.5184 · Cited by 50 · see citing works

The albino–deletion complex in the mouse defines genes necessary for development of embryonic and extraembryonic ectoderm*

Niswander, L. A., Yee, D., Rinchik, E. M., Russell, L. B., & Magnuson, T. (1989) · Development · doi:10.1242/dev.105.1.175 · Cited by 50 · see citing works

The albino deletion complex and early postimplantation survival in the mouse

Niswander, L. A., Yee, D., Rinchik, E. M., Russell, L. B., & Magnuson, T. (1988) · Development · doi:10.1242/dev.102.1.45 · Cited by 49 · see citing works

Tyrosinaemia type I and apoptosis of hepatocytes and renal tubular cells

Endo, F., & Sun, M. (2002) · Journal of Inherited Metabolic Disease · doi:10.1023/a:1015646400182 · Cited by 48 · see citing works

Transcriptional Regulation of the Phosphoenolpyruvate Carboxykinase Gene by Cooperation Between Hepatic Nuclear Factors

Yanuka-Kashles, O., Cohen, H., Trus, M., Aran, A. A., Benvenisty, N., & Reshef, L. (1994) · Molecular and Cellular Biology · doi:10.1128/mcb.14.11.7124 · Cited by 46 · see citing works

Animal Models of Tyrosinemia

Nakamura, K., Tanaka, Y., Mitsubuchi, H., & Endo, F. (2007) · Journal of Nutrition · doi:10.1093/jn/137.6.1556s · Cited by 42 · see citing works

Insulin enhances transcription of the tyrosine aminotransferase gene in rat liver

Lee, K., Isham, K. R., Johnson, A. C., & Kenney, F. T. (1986) · Archives of Biochemistry and Biophysics · doi:10.1016/0003-9861(86)90513-8 · Cited by 42 · see citing works

A Mouse Model of Renal Tubular Injury of Tyrosinemia Type 1

SUN, M.-S., Hattori, S., Kubo, S., Awata, H., Matsuda, I., & Endo, F. (2000) · Journal of the American Society of Nephrology · doi:10.1681/asn.v112291 · Cited by 41 · see citing works

Glycogen storage diseases in animals and their potential value as models of human disease

Walvoort, H. C. (1982) · Journal of Inherited Metabolic Disease · doi:10.1007/bf02391186 · Cited by 41 · see citing works

Abnormal expression of urea cycle enzyme genes in juvenile visceral steatosis (jvs) mice

Tomomura, M., Imamura, Y., Horiuchi, M., Koizumi, T., Nikaido, H., Hayakawa, J.-I., & Saheki, T. (1992) · Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease · doi:10.1016/0925-4439(92)90058-u · Cited by 41 · see citing works

Fah Knockout Animals as Models for Therapeutic Liver Repopulation

Grompe, M. (2017) · Advances in experimental medicine and biology · doi:10.1007/978-3-319-55780-9_20 · Cited by 42 · see citing works

N-Ethyl-N-nitrosourea-induced prenatally lethal mutations define at least two complementation groups within the embryonic ectoderm development (eed) locus in mouse Chromosome 7

Rinchik, E. M., & Carpenter, D. A. (1993) · Mammalian Genome · doi:10.1007/bf00360583 · Cited by 40 · see citing works

Transcriptional control in hepatocytes of normal and c14CoS albino deletion mice.

Tönjes, R. R., Xanthopoulos, K. G., Darnell, J. E., Jr., & Paul, D. (1992) · The EMBO Journal · doi:10.1002/j.1460-2075.1992.tb05035.x · Cited by 39 · see citing works

msd is required for mesoderm induction in mice

Holdener, B. C., Faust, C. J., Rosenthal, N. S., & Magnuson, T. (1994) · Development · doi:10.1242/dev.120.5.1335 · Cited by 39 · see citing works

Genetics and cancer

Ponder, B. A. J. (1980) · Biochimica et Biophysica Acta (BBA) - Reviews on Cancer · doi:10.1016/0304-419x(80)90007-4 · Cited by 39 · see citing works

Mouse albino‐deletions: From genetics to genes in development

Holdener‐Kenny, B., Sharan, S. K., & Magnuson, T. (1992) · BioEssays · doi:10.1002/bies.950141208 · Cited by 39 · see citing works

Marked increases in hepatic NAD(P)H:oxidoreductase gene transcription and mRNA levels correlated with a mouse chromosome 7 deletion.

Petersen, D. D., Gonzalez, F. J., Rapić, V., Kozak, C. A., Jong‐Youn, L. E. E., Jones, J. E., & Nebert, D. W. (1989) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.86.17.6699 · Cited by 38 · see citing works

Pleiotropy in microdeletion syndromes: neurologic and spermatogenic abnormalities in mice homozygous for the p6H deletion are likely due to dysfunction of a single gene.

Rinchik, E. M., Carpenter, D. A., & Handel, M. A. (1995) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.92.14.6394 · Cited by 36 · see citing works

The albino-deletion complex of the mouse: molecular mapping of deletion breakpoints that define regions necessary for development of the embryonic and extraembryonic ectoderm.

Sharan, S. K., Holdener‐Kenny, B., Ruppert, S., Schedl, A., Kelsey, G., Rinchik, E. M., & Magnuson, T. (1991) · Genetics · doi:10.1093/genetics/129.3.825 · Cited by 34 · see citing works

Using CRISPR/Cas9 to model human liver disease

Alves‐Bezerra, M., Furey, N., Johnson, C. G., & Bissig, K. (2019) · JHEP Reports · doi:10.1016/j.jhepr.2019.09.002 · Cited by 32 · see citing works

Comparative genetics of albinism

Searle, A. G. (1990) · Ophthalmic Paediatrics and Genetics · doi:10.3109/13816819009020974 · Cited by 33 · see citing works

Control of kidney differentiation by soluble factors secreted by the embryonic liver and the yolk sac

Ekblom, P., & Thesleff, I. (1985) · Developmental Biology · doi:10.1016/0012-1606(85)90060-0 · Cited by 33 · see citing works

Regulatory genes in development

Gluecksohn‐Waelsch, S. (1987) · Trends in Genetics · doi:10.1016/0168-9525(87)90201-0 · Cited by 33 · see citing works

Efficient liver repopulation of transplanted hepatocyte prevents cirrhosis in a rat model of hereditary tyrosinemia type I

Zhang, L., Shao, Y., Li, L., Tian, F., Cen, J., Chen, X., Hu, D. M., Zhou, Y., Xie, W., Zheng, Y., et al. (2016) · Scientific Reports · doi:10.1038/srep31460 · Cited by 32 · see citing works

Molecular mapping within the mouse albino-deletion complex.

Johnson, D. K., Hand, R. E., & Rinchik, E. M. (1989) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.86.22.8862 · Cited by 31 · see citing works

Isolation, characterization and chromosomal mapping of the mouse tyrosine aminotransferase gene

Müller, G., Scherer, G., Zentgraf, H., Ruppert, S., Herrmann, B. G., Lehrach, H. R., & Schütz, G. (1985) · Journal of Molecular Biology · doi:10.1016/0022-2836(85)90287-6 · Cited by 31 · see citing works

Metallothionein mRNA expression in mice homozygous for chromosomal deletions around the albino locus.

DeFranco, D. B., Morris, S. M., Leonard, C. M., & Gluecksohn‐Waelsch, S. (1988) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.85.4.1161 · Cited by 31 · see citing works

A systematic review of the relationship between dystemprament (sue Mizaj) and treatments and management of diseases (Ilaj and Eslah-e-Mizaj)

Miraj, S., Alesaeidi, ‬., & Kiani, S. (2016) · Electronic physician · doi:10.19082/3378 · Cited by 30 · see citing works

Functional and structural analyses of mouse genomic regions screened by the morphological specific-locus test

Russell, L. B. (1989) · Mutation research. Fundamental and molecular mechanisms of mutagenesis · doi:10.1016/0027-5107(89)90019-5 · Cited by 30 · see citing works

Assignment of the human tyrosine aminotransferase gene to chromosome 16

Natt, E., Kao, F., Rettenmeier, R., & Scherer, G. (1986) · Human Genetics · doi:10.1007/bf00291882 · Cited by 29 · see citing works

Molecular mapping of albino deletions associated with early embryonic lethality in the mouse

Niswander, L., Kelsey^, G., Schedl, A., Ruppert, S., Sharan, S. K., Holdener-Kenny, B., Rinchik, E. M., Edström, J.-E., & Magnuson, T. (1991) · Genomics · doi:10.1016/0888-7543(91)90234-6 · Cited by 28 · see citing works

Physical mapping of the albino-deletion complex in the mouse to localize alf/hsdr-1, a locus required for neonatal survival

Kelsey, G., Schedl, A., Ruppert, S., Niswander, L., Magnuson, T., Klebig, M. L., Rinchik, E. M., & Schütz, G. (1992) · Genomics · doi:10.1016/s0888-7543(05)80217-4 · Cited by 28 · see citing works

Pharmacological rescue of the 14CoS/14CoS mouse: hepatocyte apoptosis is likely caused by endogenous oxidative stress

Dieter, M. Z., Freshwater, S. L., Miller, M. L., Shertzer, H. G., Dalton, T. P., & Nebert, D. W. (2003) · Free Radical Biology and Medicine · doi:10.1016/s0891-5849(03)00273-9 · Cited by 27 · see citing works

A Quantitative-Genetics Perspective on Mammalian Development

Atchley, W. R., & Newman, S. (1989) · The American Naturalist · doi:10.1086/284993 · Cited by 27 · see citing works

Decreased Hnf-1 Gene Expression in Mice Homozygous for a 1.2-CentiMorgan Deletion on Chromosome 7

Gonzalez, F. J., Liu, S., Kozak, C. A., & Nebert, D. W. (1990) · DNA and Cell Biology · doi:10.1089/dna.1990.9.771 · Cited by 27 · see citing works

Type I Oculocutaneous Albinism Associated with a Full-Length Deletion of the Tyrosinase Gene

Schnur, R. E., Sellinger, B., Holmes, S. A., Wick, P. A., Tatsumura, Y. O., & Spritz, R. A. (1996) · Journal of Investigative Dermatology · doi:10.1111/1523-1747.ep12340185 · Cited by 25 · see citing works

Turnover of embryonic messenger RNA in preimplantation mouse embryos

Kidder, G. M., & Pedersen, R. A. (1982) · Development · doi:10.1242/dev.67.1.37 · Cited by 25 · see citing works

in Female Patients of Iranian Descent

Leiomyoma, S. T. U., Mortezaee, F. T., Sc, M. E. B., Tabatabaiefar, M. A., Ph., D., Chaleshtori, H., Ph., D., Miraj, S., Citation Taghizade Mortezaee, F., Ma, T., et al. (2016)

Is genetic polymorphism of ER-α, CYP1A1, and CYP1B1 a risk factor for uterine leiomyoma?

El-Shennawy, G., Elbialy, A. A., Isamil, A. E., & Behery, M. M. E. (2010) · Archives of Gynecology and Obstetrics · doi:10.1007/s00404-010-1550-x · Cited by 28 · see citing works

Combination effect of cytochrome P450 1A1 gene polymorphisms on uterine leiomyoma: A case-control study

Salimi, S., Sajadian, M., Khodamian, M., Yazdi, A., Rezaee, S., Mohammadpour‐Gharehbagh, A., Mokhtari, M., & Yaghmaie, M. (2016) · Bosnian Journal of Basic Medical Sciences · doi:10.17305/bjbms.2016.1245 · Cited by 7 · see citing works

Susceptibility of Estrogen Receptor Alpha Gene Polymorphism Towards Uterine Leiomyoma Development

Narwal, S., Vashist, M., Kaushik, R., Siwach, K., & Hooda, R. (2024) · Journal of Cancer Science and Clinical Therapeutics · doi:10.26502/jcsct.5079245

The effects of p21 gene C98A polymorphism on development of uterine leiomyoma in southeast Iranian women

Salimi, S., Hajizadeh, A., Yaghmaei, M., Rezaie, S., Shahrakypour, M., Teimoori, B., Parache, M., Naghavi, A., & Mokhtari, M. (2016) · Tumor Biology · doi:10.1007/s13277-016-5078-y · Cited by 8 · see citing works