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Cited by 407Diabetes and associated disordersDiabetes Management and ResearchDiabetes, Cardiovascular Risks, and Lipoproteins

The DOI matches its Crossref record; 24 of the 24 references it cites were found in a registry or an index.

Incidence of childhood-onset insulin-dependent diabetes mellitus: the EURODIAB ACE study

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Green, A., Gale, E.A.M., Patterson, C.C.·1992·The Lancet
DOI 10.1016/0140-6736(92)90938-y
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Abstract

EURODIAB ACE is a collaborative European study that was set up to assess incidence of childhood insulin-dependent diabetes mellitus (IDDM) in Europe, test the proposal of a south-north gradient, and to gather information to determine the causes and pathogenesis of the disease. Here, the basic epidemiological results are reported. Newly diagnosed cases of IDDM in children aged up to 15 years were identified prospectively in twenty-four geographically well-defined study regions in Europe and Israel (a total of 16.8 million children) during 1989 and 1990. 3060 cases were identified with estimated ascertainment rates exceeding 90% in all study regions. Age-standardised and sex-standardised incidence rates varied widely, ranging from 4.6 (northern Greece) to 42.9 (two regions in Finland) cases per 100,000 per year. Rates in southern Europe were generally higher than previously assumed, and there was an unexpectedly high incidence in Sardinia, which had the second highest rate (30.2 cases per 100,000 per year) recorded in Europe. Eastern European regions had generally low rates. The collaborative network now established provides a framework for further studies to examine the complex interaction between genetic and environmental factors in the cause and pathogenesis of IDDM.

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Citations

Cites

Show all 23 references

Research works printed but not linked: 7

  1. Green, 1986, Workshop on diabetes registers: the role of IDDM registers in diabetes research and care, 443
  2. Lestradet, 1977, Prévalence et incidence du diabète juvénile insulinodépendant en France, Diabète Métab, 3, 29
  3. Hours, 1984, Diabète insulino-dépendant juvénile: etute descriptive dans le départment du Rhône, Rev Epidémiol et Santé Public, 32, 107
  4. Av Thorsson, T. Helgason, Mr Jonasson, R. Danielsen, Childhood diabetes in Iceland in the last two decades (Presentation at International Symposium on Epidemiology and Etiology of IDDM in the Young, France, May 1991).
  5. A. Green, Eam Gale, The aetiology and pathogenesis of insulin-dependent diabetes: an epidemiological perspective In: J. Fuller, R. Williams, L. Papoz (Eds), Diabetes in Europe, John Libby, London ((in press)).
  6. Shubnikov, 1991, Incidence of childhood IDDM in the city of Novosibirsk during 1985-1987, Diabetes, 40, abstr 1253
  7. Carcassi, 1990, An HLA-DR2 haplotype confers susceptibility to Type 1 diabetes in Sardinia, Diabetes, 39, abstr 60

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Metadata

Authors
Green, A., Gale, E. A. M., & Patterson, C. C.
Affiliations
  • University of Southern Denmark (DK)
  • St Bartholomew's Hospital (GB)
  • Queen's University Belfast (GB)
Corresponding author
Green, A.
ORCID
Venue
The Lancet
Publisher
Elsevier BV
Published
1992-04
Volume
339
Issue
8798
Pages
905-909
ISSN
  • 0099-5355 (ISSN-L)
  • 0140-6736
DOI
10.1016/0140-6736(92)90938-y
OpenAlex
W2008539299
Cited by
407
References
23
Citations by year
2025: 2 · 2024: 5 · 2023: 5 · 2022: 6 · 2021: 3 · 2020: 2 · 2019: 7 · 2018: 9 · 2017: 7 · 2016: 11 · 2015: 11 · 2014: 9 · 2013: 7 · 2012: 10
FWCI
11.39
Type
journal article
Language
en
Open access
Licence
Locations
  • The Lancet (publishedVersion)
  • PubMed (publishedVersion)
  • Open Repository and Bibliography (University of Luxembourg) (submittedVersion, cc-by-nc-sa)
  • VUBIR (Vrije Universiteit Brussel) (submittedVersion)
Topics
  • Life Sciences › Biochemistry, Genetics and Molecular Biology › Genetics › Diabetes and associated disorders
  • Health Sciences › Medicine › Endocrinology, Diabetes and Metabolism › Diabetes Management and Research
  • Health Sciences › Medicine › Endocrinology, Diabetes and Metabolism › Diabetes, Cardiovascular Risks, and Lipoproteins
Keywords
type 1 diabetes, childhood-onset diabetes, incidence, age-standardized incidence rate, Sardinia, genetic and environmental risk factors, pathogenesis
MeSH terms
Adolescent, Child, Child, Preschool, Diabetes Mellitus, Type 1, Epidemiologic Methods, Europe, Female, Humans, Infant, Israel, Male, Prospective Studies

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