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Interaction of cultured human endothelial cells with polymeric surfaces of different wettabilities
Open accessAbstract
The in vitro interaction of human endothelial cells (HEC) and polymers with different wettabilities in culture medium containing serum was investigated. Optimal adhesion of HEC generally occurred onto moderately wettable polymers. Within a series of cellulose type of polymers the cell adhesion increased with increasing contact angle of the polymer surfaces. Proliferation of HEC occurred when adhesion was followed by progressive flattening of the cells. Our results suggest that moderately wettable polymers exhibit a serum and/or cellular protein adsorption pattern that is favourable for growth of HEC.
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Cites
Role of cell shape in growth control
Folkman, J., & Moscona, A. (1978) · Nature · doi:10.1038/273345a0 · Cited by 2,422
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Physicochemical Foundations and Structural Design of Hydrogels in Medicine and Biology
Peppas, N. A., Huang, Y., Torres-Lugo, M., Ward, J. H., & Zhang, J. (2000) · Annual Review of Biomedical Engineering · doi:10.1146/annurev.bioeng.2.1.9 · Cited by 1,016
The biocompatibility of novel starch-based polymers and composites: in vitro studies
Marques, A. P., Reis, R. L., & Hunt, J. A. (2002) · Biomaterials · doi:10.1016/s0142-9612(01)00272-1 · Cited by 347
Liu, X., Lim, J. Y., Donahue, H. J., Dhurjati, R., Mastro, A. M., & Vogler, E. A. (2007) · Biomaterials · doi:10.1016/j.biomaterials.2007.06.016 · Cited by 321
Genipin-crosslinked chitosan/gelatin blends for biomedical applications
Chiono, V., Pulieri, E., Vozzi, G., Ciardelli, G., Ahluwalia, A., & Giusti, P. (2008) · Journal of Materials Science: Materials in Medicine · doi:10.1007/s10856-007-3212-5 · Cited by 297
Metadata
- Authors
- van Wachem, P. B., Beugeling, T., Feijen, J., Bantjes, A., Detmers, J. P., & van Aken, W. G.
- Venue
- Biomaterials
- Publisher
- Elsevier BV
- Published
- 1985-11
- Volume
- 6
- Issue
- 6
- Pages
- 403-408
- ISSN
- 0142-9612 (ISSN-L)
- OpenAlex
- W2086277592
- Cited by
- 591
- References
- 1
- FWCI
- 3.48
- Type
- journal article
- Language
- en
- Open access
- green
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- van Wachem, P. B., Beugeling, T., Feijen, J., Bantjes, A., Detmers, J. P., & van Aken, W. G. (1985). Interaction of cultured human endothelial cells with polymeric surfaces of different wettabilities. Biomaterials. https://doi.org/10.1016/0142-9612(85)90101-2
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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.