The DOI matches its Crossref record; 9 of the 9 references it cites were found in a registry or an index.
Peroxide accumulation in detergents
Abstract
It is known that polyether detergents have a propensity for peroxide accumulation but the rate of this accumulation and the conditions under which it occurs are not well-appreciated. We here describe the use of the FOX (ferrous oxidation in Xylenol orange) assay as a screen for detergent peroxide accumulation. We also show that a chain-breaking antioxidant, but not a metal-chelating agent block peroxide accumulation in detergent stored in the light at room temperature.
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Lipid oxidation can occur in unsaturated fatty acid moieties, which are not present in Comirnaty and mRNA-1273, and with cholesterol, potentially as a result of a hydroperoxide attack or an impurity present in the PEG-group of PEG2000-C-DMG.
“Lipid oxidation can occur in unsaturated fatty acid moieties (not present in Comirnaty and mRNA-1273) and with cholesterol, potentially as a result of a hydroperoxide attack, an impurity present in the PEG-group of PEG2000-C-DMG (Jaeger et al., 1994, Wang et al., 2019).”
From mRNA-lipid nanoparticle COVID-19 vaccines: structure and stability (2021) · cites this paper as Jaeger et al., 1994
Citations
Cites
Jiang, Z. Y., Hunt, J. V., & Wolff, S. P. (1992) · Analytical Biochemistry · doi:10.1016/0003-2697(92)90122-n · Cited by 1,624
Self-citationJiang, Z. Y., Woollard, A. C. S., & Wolff, S. P. (1991) · Lipids · doi:10.1007/bf02536169 · Cited by 636
Self-citationHydrogen peroxide production during experimental protein glycation
Jiang, Z. Y., Woollard, A. C. S., & Wolff, S. P. (1990) · FEBS Letters · doi:10.1016/0014-5793(90)80974-n · Cited by 518
Self-citationHighly reactive impurities in Triton X-100 and Brij 35: Partial characterization and removal
Ashani, Y., & Catravas, G. N. (1980) · Analytical Biochemistry · doi:10.1016/0003-2697(80)90009-3 · Cited by 126
Chang, H. W., & Bock, E. (1980) · Analytical Biochemistry · doi:10.1016/0003-2697(80)90283-3 · Cited by 112
Peroxides in detergents as interfering factors in biochemical analysis
Lever, M. (1977) · Analytical Biochemistry · doi:10.1016/0003-2697(77)90536-x · Cited by 63
Interference of the detergent Tween 80 in protein assays
Stutzenberger, F. J. (1992) · Analytical Biochemistry · doi:10.1016/0003-2697(92)90008-u · Cited by 23
Soybean lipoxygenase catalysed oxygenation of unsaturated fatty acid encapsulated in cyclodextrin
Jyothirmayi, N., & Ramadoss, C. S. (1991) · Biochimica et Biophysica Acta (BBA) - Lipids and Lipid Metabolism · doi:10.1016/0005-2760(91)90042-g · Cited by 14
The reaction of horseradish peroxidase with hydroperoxides derived from Triton X-100
Miki, T., & Orii, Y. (1985) · Analytical Biochemistry · doi:10.1016/0003-2697(85)90390-2 · Cited by 14
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mRNA-lipid nanoparticle COVID-19 vaccines: structure and stability
Schoenmaker, L., Witzigmann, D., Kulkarni, J. A., Verbeke, R., Kersten, G., Jiskoot, W., & Crommelin, D. J. A. (2021) · International Journal of Pharmaceutics · doi:10.1016/j.ijpharm.2021.120586 · Cited by 1,566
Metadata
- Authors
- Jaeger, J., Sorensen, K., & Wolff, S. P.
- Affiliations
- University College London (GB)
- Corresponding author
- Wolff, S.P.
- Venue
- Journal of Biochemical and Biophysical Methods
- Publisher
- Elsevier BV
- Published
- 1994-07
- Volume
- 29
- Issue
- 1
- Pages
- 77-81
- ISSN
- 0165-022X (ISSN-L)
- OpenAlex
- W2089109336
- Cited by
- 68
- References
- 9
- Citations by year
- 2026: 1 · 2025: 1 · 2024: 3 · 2023: 1 · 2022: 4 · 2021: 5 · 2020: 1 · 2018: 6 · 2017: 4 · 2016: 2 · 2015: 3 · 2014: 3 · 2013: 3 · 2012: 4
- FWCI
- 0.62
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- Journal of Biochemical and Biophysical Methods (publishedVersion)
- PubMed (publishedVersion)
- Topics
- Physical Sciences › Chemistry › Physical and Theoretical Chemistry › Surfactants and Colloidal Systems
- Physical Sciences › Chemistry › Organic Chemistry › Free Radicals and Antioxidants
- Physical Sciences › Environmental Science › Environmental Chemistry › Environmental Chemistry and Analysis
- Keywords
- peroxide accumulation, chain-breaking antioxidants, chelating agents, light exposure
- MeSH terms
- Butylated Hydroxytoluene, Darkness, Detergents, Drug Contamination, Drug Stability, Fluorescent Dyes, Kinetics, Light, Oxidation-Reduction, Peroxides, Phenols, Polysorbates, Sulfoxides, Time Factors, Xylenes, Octoxynol
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