Outpatient utilization of antidepressants: a prescription database analysis
Abstract
A prescription database analysis was conducted to describe the users of antidepressants outside hospitals in the Odense area (207,000 inhabitants) during one year. In total, 1.62% (N = 3360) of the population used antidepressants. Women and users aged over 70 years constituted a disproportionately large part. Seventy-five percent of the patients used tricyclic antidepressants. The estimated daily doses for the tricyclic antidepressants were generally low, the third quartile being less than 100 mg daily. The low doses may be due to antidepressants being used on other indications than depression or that a considerable number of the patients are not given a sufficient dose.
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A few studies suggested that older antidepressants such as TCAs were more susceptible to be prescribed in low doses.
“A few studies suggested that older antidepressants such as TCAs were more susceptible to be prescribed in low doses (34, 38, 39), which was consistent with our study.”
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- Authors
- Rosholm, J.-U., Hallas, J., & Gram, L. F.
- Affiliations
- University of Southern Denmark (DK)
- Corresponding author
- Rosholm, J.-U.
- ORCID
- Hallas, J.
- Venue
- Journal of Affective Disorders
- Publisher
- Elsevier BV
- Published
- 1993-01
- Volume
- 27
- Issue
- 1
- Pages
- 21-28
- ISSN
- 0165-0327 (ISSN-L)
- OpenAlex
- W2060383216
- Cited by
- 48
- References
- 22
- Citations by year
- 2020: 1 · 2013: 1
- FWCI
- 8.56
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- Journal of Affective Disorders (publishedVersion)
- PubMed (publishedVersion)
- Funders
- Instytut Biologii Medycznej Polskiej Akademii Nauk
- Topics
- Social Sciences › Psychology › Social Psychology › Mental Health Treatment and Access
- Health Sciences › Medicine › Pharmacology › Treatment of Major Depression
- Health Sciences › Medicine › Geriatrics and Gerontology › Pharmaceutical Practices and Patient Outcomes
- Keywords
- antidepressants, prescribing patterns, tricyclic antidepressants, antidepressant dosing, depression, women, elderly patients, Odense
- MeSH terms
- Adult, Aged, Aged, 80 and over, Antidepressive Agents, Antidepressive Agents, Tricyclic, Denmark, Drug Utilization, Female, Humans, Male, Middle Aged, Drug Prescriptions, Databases, Factual
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