Cited by 33Circadian rhythm and melatoninTreatment of Major DepressionLight effects on plants

Effects of green or white light for treatment of seasonal depression.

Stewart, Karen T., Gaddy, James R., Byrne, Brenda, Miller, Sharon, Brainard, George C.·1991·Psychiatry Research

Abstract

Twelve subjects with winter depression were treated with equal quanta of green or white light in a randomized crossover study. Each treatment condition consisted of 2 hours of exposure each morning for 1 week, with at least 1 interventing week without treatment. Ratings made without knowledge of treatment condition were done before and after each condition. Both treatments significantly reduced depression ratings. White light was significantly more effective than green light in reducing endogenous symptoms, but not the "atypical" symptoms that are common features of winter depression. Furthermore, sequence of treatment conditions influenced antidepressant responses. Broad-band white light may be optimal for maximizing therapeutic response.

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Authors
Stewart, K. T., Gaddy, J. R., Byrne, B., Miller, S., & Brainard, G. C.
Affiliations
  • Rush University Medical Center (US)
  • Thomas Jefferson University (US)
  • United States Food and Drug Administration (US)
Corresponding author
Brainard, George C.
Venue
Psychiatry Research
Publisher
Elsevier BV
Published
1991-09
Volume
38
Issue
3
Pages
261-270
ISSN
0165-1781 (ISSN-L)
OpenAlex
W2052987399
Cited by
33
References
2
Citations by year
2025: 1 · 2024: 1 · 2020: 1 · 2019: 1 · 2017: 1 · 2016: 1 · 2014: 1 · 2013: 1
FWCI
1.41
Type
journal article
Language
en
Open access
closed
Locations
  • Psychiatry Research (publishedVersion)
  • PubMed (publishedVersion)
Funders
  • National Institutes of Health (1r03mh044890-01a1)
  • National Institute of Mental Health (R03-MH-44890-01A1)
Topics
  • Life Sciences › Neuroscience › Endocrine and Autonomic Systems › Circadian rhythm and melatonin
  • Health Sciences › Medicine › Pharmacology › Treatment of Major Depression
  • Life Sciences › Agricultural and Biological Sciences › Plant Science › Light effects on plants
Keywords
seasonal affective disorder, phototherapy, green light, white light, light color, antidepressant response
MeSH terms
Adult, Analysis of Variance, Color, Female, Humans, Light, Male, Phototherapy, Time Factors, Seasonal Affective Disorder

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