The DOI matches its Crossref record; 2 of the 2 references it cites were found in a registry or an index.
Blood-borne interleukin-1 receptor antagonist crosses the blood-brain barrier
Overview
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Integrity signals
Registry
Cites
Statistics
Verification
Claims the paper makes
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Self-check
Percentages, sums and reported differences re-computed from the paper’s own numbers.
The self-check needs the paper’s full text.
Citations
Cites
Murine tumor necrosis factor alpha is transported from blood to brain in the mouse
Gutierrez, E. G., Banks, W. A., & Kastin, A. J. (1993) · Journal of Neuroimmunology · doi:10.1016/0165-5728(93)90027-v · Cited by 577
Self-citationBanks, W. A., Ortiz, L., Plotkin, S. R., & Kastin, A. J. (1991) · The Journal of Pharmacology and Experimental Therapeutics · doi:10.1016/s0022-3565(25)20576-6 · Cited by 474 · cited 1×
“Generally, proteins are restricted from crossing the BBB, but IL-lc~ (Banks et al., 1989) and 1L-l/3 (Banks et al., 1991) have been shown to be transported across the BBB by a saturable system (Banks and Kastin, 1991).”
BackgroundSelf-citation
Cited by
Regulation of the Hypothalamic-Pituitary-Adrenal Axis by Cytokines: Actions and Mechanisms of Action
TURNBULL, A. V., & RIVIER, C. L. (1999) · Physiological Reviews · doi:10.1152/physrev.1999.79.1.1 · Cited by 1,297
CAR T cell–induced cytokine release syndrome is mediated by macrophages and abated by IL-1 blockade
Giavridis, T., van der Stegen, S. J. C., Eyquem, J., Hamieh, M., Piersigilli, A., & Sadelain, M. (2018) · Nature Medicine · doi:10.1038/s41591-018-0041-7 · Cited by 1,272
Cytokines and acute neurodegeneration
Allan, S. M., & Rothwell, N. J. (2001) · Nature Reviews Neuroscience · doi:10.1038/35094583 · Cited by 1,123
INTERLEUKIN-1 RECEPTOR ANTAGONIST: Role in Biology
Arend, W. P., Malyak, M., Guthridge, C. J., & Gabay, C. (1998) · Annual Review of Immunology · doi:10.1146/annurev.immunol.16.1.27 · Cited by 1,071
The balance between IL-1 and IL-1Ra in disease
Arend, W. P. (2002) · Cytokine & Growth Factor Reviews · doi:10.1016/s1359-6101(02)00020-5 · Cited by 721
Metadata
- Authors
- GUTIERREZ, E., BANKS, W., & KASTIN, A.
- Venue
- Journal of Neuroimmunology
- Publisher
- Elsevier BV
- Published
- 1994-12
- Volume
- 55
- Issue
- 2
- Pages
- 153-160
- ISSN
- 0165-5728 (ISSN-L)
- OpenAlex
- W2074229539
- Cited by
- 175
- References
- 2
- FWCI
- 2.79
- Type
- journal article
- Language
- en
- Open access
- closed
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
Are you an author, or do you see a problem with this page? Request a review
How to cite
Cite CoChat for the checks on this page, and the paper for its own findings.
- This page
- CoChat. (2026). Citation check: Blood-borne interleukin-1 receptor antagonist crosses the blood-brain barrier. https://app.cochat.ai/papers/10.1016/0165-5728(94)90005-1
- The paper
- GUTIERREZ, E., BANKS, W., & KASTIN, A. (1994). Blood-borne interleukin-1 receptor antagonist crosses the blood-brain barrier. Journal of Neuroimmunology. https://doi.org/10.1016/0165-5728(94)90005-1
Data sources
Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
