Autocatalytic replication of polymers
Integrity signals
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Claims the paper makes
Claims other papers make about this one
Each is checked against this paper’s own text: does it say what the citing paper says it does?
A catalytically closed network is endowed with self-reproduction capacities, but homeostatic growth is not directly addressed.
“It is then argued that a catalytically closed network is endowed with self-reproduction capacities, but homeostatic growth is not directly addressed (see §5.1).”
From Systems protobiology: origin of life in lipid catalytic networks (2018) · cites this paper as [38]
In Kauffman's basic model, when a system reaches a sufficiently large diversity of molecule types, autocatalytic sets appear spontaneously.
“It is then shown that when a system reaches a sufficiently large diversity of molecule types, autocatalytic sets would appear spontaneously.”
From Systems protobiology: origin of life in lipid catalytic networks (2018) · cites this paper as [38]
Catalytically closed networks have the property of catalytic closure, whereby the formation of every molecule is endogenously catalysed.
“These will have the property of ‘catalytic closure’, whereby the formation of every molecule is endogenously catalysed.”
From Systems protobiology: origin of life in lipid catalytic networks (2018) · cites this paper as [38]
Cites
Selforganization of matter and the evolution of biological macromolecules
Eigen, M. (1971) · Die Naturwissenschaften · doi:10.1007/bf00623322 · Cited by 3,788 · see citing works
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Segré, D., Ben-Eli, D., Deamer, D. W., & Lancet, D. (2001) · Origins of life and evolution of the biosphere · doi:10.1023/a:1006746807104 · Cited by 620 · see citing works
Compositional genomes: Prebiotic information transfer in mutually catalytic noncovalent assemblies
Segré, D., Ben-Eli, D., & Lancet, D. (2000) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.97.8.4112 · Cited by 398 · see citing works
Vasas, V., Fernando, C., Santos, M., Kauffman, S., & Szathmáry, E. (2012) · Biology Direct · doi:10.1186/1745-6150-7-1 · Cited by 369 · see citing works
Self-citationRules for Modeling Signal-Transduction Systems
Hlavacek, W. S., Faeder, J. R., Blinov, M. L., Posner, R. G., Hucka, M., & Fontana, W. (2006) · Science's STKE · doi:10.1126/stke.3442006re6 · Cited by 350 · see citing works
Systems protobiology: origin of life in lipid catalytic networks
Lancet, D., Zidovetzki, R., & Markovitch, O. (2018) · Journal of The Royal Society Interface · doi:10.1098/rsif.2018.0159 · Cited by 182 · see citing works
Segré, D., & Lancet, D. (2000) · The EMBO Reports · doi:10.1093/embo-reports/kvd063 · Cited by 133 · see citing works
Origins of life: a problem for physics, a key issues review
Walker, S. I. (2017) · Reports on Progress in Physics · doi:10.1088/1361-6633/aa7804 · Cited by 94 · see citing works
“Farmer et al estimated the critical probability for this phase transition to occur to be [84]:”
BackgroundRibó, J. M., Blanco, C., Crusats, J., El‐Hachemi, Z., Hochberg, D., & Moyano, A. (2014) · Chemistry – A European Journal · doi:10.1002/chem.201404534 · Cited by 81 · see citing works
Metabolism and the problem of its universalization
Bergareche, A. M., & Ruiz-Mirazo, K. (1999) · Biosystems · doi:10.1016/s0303-2647(98)00034-3 · Cited by 78 · see citing works
Adaptive Dynamic Networks as Models for the Immune System and Autocatalytic Sets
FARMER, J. D., KAUFFMAN, S. A., PACKARD, N. H., & PERELSON, A. S. (1987) · Annals of the New York Academy of Sciences · doi:10.1111/j.1749-6632.1987.tb48728.x · Cited by 59 · see citing works
Self-citationFundamental constraints to the logic of living systems
Solé, R., Kempes, C. P., Corominas-Murtra, B., De Domenico, M., Kolchinsky, A., Lachmann, M., Libby, E., Saavedra, S., Smith, E., & Wolpert, D. (2024) · Interface Focus · doi:10.1098/rsfs.2024.0010 · Cited by 34 · see citing works
The basic reproductive ratio of life
Manapat, M. L., Chen, I. A., & Nowak, M. A. (2010) · Journal of Theoretical Biology · doi:10.1016/j.jtbi.2009.12.020 · Cited by 19 · see citing works
Mutations and Lethality in Simulated Prebiotic Networks
Inger, A., Solomon, A., Shenhav, B., Olender, T., & Lancet, D. (2009) · Journal of Molecular Evolution · doi:10.1007/s00239-009-9281-y · Cited by 14 · see citing works
- Authors
- Farmer, J. D., Kauffman, S. A., & Packard, N. H.
- Affiliations
- Los Alamos National Laboratory (US)
- University of Pennsylvania (US)
- Institute for Advanced Study (US)
- Venue
- Physica D: Nonlinear Phenomena
- Publisher
- Elsevier BV
- Published
- 1986-10
- Volume
- 22
- Issue
- 1-3
- Pages
- 50-67
- ISSN
- 0167-2789 (ISSN-L)
- OpenAlex
- W2171303401
- Cited by
- 249
- References
- 1
- Citations by year
- 2026: 3 · 2025: 5 · 2024: 3 · 2023: 8 · 2022: 5 · 2021: 8 · 2020: 10 · 2019: 4 · 2018: 7 · 2017: 9 · 2016: 8 · 2015: 8 · 2014: 14 · 2013: 7 · 2012: 9
- FWCI
- 1.78
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- Physica D Nonlinear Phenomena (publishedVersion)
- Topics
- Physical Sciences › Physics and Astronomy › Astronomy and Astrophysics › Origins and Evolution of Life
- Physical Sciences › Computer Science › Computational Theory and Mathematics › Cellular Automata and Applications
- Life Sciences › Biochemistry, Genetics and Molecular Biology › Genetics › Evolution and Genetic Dynamics
- Keywords
- autocatalytic sets, polymer replication, origin of life, primitive metabolism, polypeptides, nucleic acids, self-replicating systems, chemical reaction networks
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
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