Late onset atrioventricular nodal tachycardia
Abstract
AV nodal tachycardia may present at any age, but onset in late adulthood is considered uncommon. To evaluate whether onset of AV nodal tachycardias at older age is related to organic heart disease (possibly setting the stage for re-entry due to degenerative structural changes) 32 consecutive patients with symptomatic AV nodal tachycardia were studied. The age at onset of attacks showed a bimodal pattern, with 2 peaks: one between 15 and 35 years (22 patients) and one around 55 years (10 patients). Significantly more older patients had an underlying heart disease (60% versus 14%, P < 0.01), with coronary artery disease in 4 and hypertensive heart disease in 3. Frequent supraventricular ectopic activity was seen during baseline 24-h ambulatory monitoring in all the older patients, versus in only half of the younger patients (P = 0.005). These results indicate that late onset AV nodal tachycardia (i.e. > age 45 years) is not infrequent (33%). The frequent supraventricular arrhythmias on one hand and age-related structural AV nodal changes, potentially enhanced by underlying heart disease on the other, both may contribute to the development of late onset re-entrant AV nodal tachycardia.
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The onset of atrioventricular nodal reentrant tachycardia appears to occur bimodally over time.
“Onset of AVNRT seems to occur bimodally over time.”
From European Heart Rhythm Association (EHRA) consensus document on the management of supraventricular arrhythmias, endorsed by Heart Rhythm Society (HRS), Asia-Pacific Heart Rhythm Society (APHRS), and Sociedad Latinoamericana de Estimulacion Cardiaca y Electrofisiologia (SOLAECE) (2017) · cites this paper as [223]
In many patients, attacks manifest early in life, while in a substantial proportion atrioventricular nodal reentrant tachycardia starts only in the fourth or fifth decade.
“In many patients attacks indeed manifest early in life, whereas in a substantial proportion of patients AVNRT starts only in the 4th or 5th decade.223”
From European Heart Rhythm Association (EHRA) consensus document on the management of supraventricular arrhythmias, endorsed by Heart Rhythm Society (HRS), Asia-Pacific Heart Rhythm Society (APHRS), and Sociedad Latinoamericana de Estimulacion Cardiaca y Electrofisiologia (SOLAECE) (2017) · cites this paper as [223]
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- Authors
- Pentinga, M. L., Meeder, J. G., Crijns, H. J. G. M., de Muinck, E. D., Wiesfeld, A. C. P., & Lie, K. I.
- Affiliations
- University Medical Center Groningen (NL)
- Venue
- International Journal of Cardiology
- Publisher
- Elsevier BV
- Published
- 1993-03
- Volume
- 38
- Issue
- 3
- Pages
- 293-298
- ISSN
- 0167-5273 (ISSN-L)
- OpenAlex
- W2104537493
- Cited by
- 19
- References
- 18
- Citations by year
- 2026: 1 · 2024: 1 · 2023: 3 · 2022: 1 · 2021: 1 · 2020: 1 · 2019: 1 · 2017: 1 · 2016: 3
- FWCI
- 0.63
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- International Journal of Cardiology (publishedVersion)
- PubMed (publishedVersion)
- University of Groningen research database (University of Groningen / Centre for Information Technology) (submittedVersion)
- Topics
- Health Sciences › Medicine › Cardiology and Cardiovascular Medicine › Cardiac Arrhythmias and Treatments
- Health Sciences › Medicine › Cardiology and Cardiovascular Medicine › Cardiac electrophysiology and arrhythmias
- Health Sciences › Medicine › Cardiology and Cardiovascular Medicine › Heart Rate Variability and Autonomic Control
- Keywords
- atrioventricular nodal tachycardia, late onset, age of onset, organic heart disease, coronary artery disease, hypertensive heart disease, reentrant tachycardia, 24-hour ambulatory monitoring
- MeSH terms
- Adult, Age Factors, Cardiac Pacing, Artificial, Electrocardiography, Female, Heart Conduction System, Heart Diseases, Humans, Male, Middle Aged, Tachycardia, Atrioventricular Nodal Reentry, Electrocardiography, Ambulatory
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