The DOI matches its Crossref record; 13 of the 13 references it cites were found in a registry or an index.
Obesity and left ventricular diastolic dysfunction
Abstract
To assess the influence of obesity on left ventricular function, 20 obese women (mean body mass index (BMI) 33.8 +/- 3.1 kg/m2 and mean age 31.1 +/- 2.4 years) without evidence of heart disease were evaluated by echocardiography. Obese subjects had greater left ventricular mass index (103 +/- 22 g/m2, 76 +/- 18 g/m2; P < 0.0001) and augmented fractional shortening (39 +/- 2.6%, 36 +/- 0.1%; P < 0.0001) than normals. Isovolumic relaxation time was prolonged in the obese group (92 +/- 11 ms) as compared with the control group (76 +/- 11 ms; P < 0.0001). The ratio of peak early and atrial filling velocities was significantly lower (1.2 +/- 0.4, 1.9 +/- 0.6; P < 0.0001) and atrial contribution was higher (39 +/- 9, 25 +/- 5; P < 0.0001) in obese subjects than in normals. Shortened deceleration time was measured in obese subjects (142 +/- 30, 179 +/- 20 ms; P < 0.0001). In conclusion, obesity causes relaxation and early filling abnormalities and diastolic filling is compensated by augmented atrial contribution. Diastolic dysfunction is an early indicator of cardiac involvement in obesity.
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In the citing paper
“Many published studies have concluded that obesity is independently associated with LV hypertrophy (22, 28, 63, 72, 116, 235, 242, 266, 279, 284, 377).”
From Cardiac remodeling in obesity (2008) · cites this paper as [28]
In the citing paper
“More recently, however, several studies have found that LV ejection fraction is normal or even supranormal in the majority of obese subjects, even those with severe obesity (22, 28, 155, 191, 242, 274, 279, 375, 377).”
From Cardiac remodeling in obesity (2008) · cites this paper as [28]
In the citing paper
“Lastly, late diastolic (A-wave) velocities have been reported to be increased (28, 155, 242) or unchanged (266, 274, 279, 314).”
From Cardiac remodeling in obesity (2008) · cites this paper as [28]
In the citing paper
“Prolongation of the isovolumic relaxation time is probably the most consistent diastolic abnormality seen in obesity (28, 242, 375).”
From Cardiac remodeling in obesity (2008) · cites this paper as [28]
Citations
Cites
Echocardiographic determination of left ventricular mass in man. Anatomic validation of the method.
Devereux, R. B., & Reichek, N. (1977) · Circulation · doi:10.1161/01.cir.55.4.613 · Cited by 4,499
DIVITIIS, O. D., Fazio, S., Petitto, M., Maddalena, G., Contaldo, F., & Mancini, M. (1981) · Circulation · doi:10.1161/01.cir.64.3.477 · Cited by 394
Dimorphic Cardiac Adaptation to Obesity and Arterial Hypertension
Messerli, F. H., SUNDGAARD-RIISE, K., REISIN, E. D., DRESLINSKI, G. R., Ventura, H. O., OIGMAN, W., FROHLICH, E. D., & DUNN, F. G. (1983) · Annals of Internal Medicine · doi:10.7326/0003-4819-99-6-757 · Cited by 336
CARDIOVASCULAR EFFECTS OF OBESITY AND HYPERTENSION
Messerli, F. (1982) · The Lancet · doi:10.1016/s0140-6736(82)92234-6 · Cited by 235
Alpert, M. A., Terry, B. E., & Kelly, D. L. (1985) · The American Journal of Cardiology · doi:10.1016/0002-9149(85)90156-0 · Cited by 210
Disparate cardiovascular effects of obesity and arterial hypertension
Messerli, F. H., Sundgaard-Riise, K., Reisin, E., Dreslinski, G. R., Dunn, F. G., & Frohlich, E. D. (1983) · The American Journal of Medicine · doi:10.1016/0002-9343(83)91071-9 · Cited by 197
The Cardiac Pathology of Chronic Exogenous Obesity
Amad, K. H., Brennan, J. C., & Alexander, J. K. (1965) · Circulation · doi:10.1161/01.cir.32.5.740 · Cited by 183
Nakajima, T., Fujioka, S., Tokunaga, K., Hirobe, K., Matsuzawa, Y., & Tarui, S. (1985) · Circulation · doi:10.1161/01.cir.71.3.481 · Cited by 108
Abnormal left ventricular diastolic filling in eccentric left ventricular hypertrophy of obesity
Chakko, S. C., Mayor, M., Allison, M. D., Kessler, K. M., Materson, B. J., & Myerburg, R. J. (1991) · The American Journal of Cardiology · doi:10.1016/0002-9149(91)90718-z · Cited by 103
The influence of obesity on left ventricular filling and systolic function
Stoddard, M. F., Tseuda, K., Thomas, M., Dillon, S., & Kupersmith, J. (1992) · American Heart Journal · doi:10.1016/0002-8703(92)90280-9 · Cited by 96
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Lacôte, M. (2018) · theses.fr (ABES) · doi:10.70675/bc9b8426z5718z40e1zadc2zaa52fb20a6fd
Metadata
- Authors
- Berkalp, B., Cesur, V., Corapcioglu, D., Erol, C., & Baskal, N.
- Affiliations
- Ankara University (TR)
- Corresponding author
- Berkalp, Berkten
- Venue
- International Journal of Cardiology
- Publisher
- Elsevier BV
- Published
- 1995-11
- Volume
- 52
- Issue
- 1
- Pages
- 23-26
- ISSN
- 0167-5273 (ISSN-L)
- OpenAlex
- W2128710157
- Cited by
- 102
- References
- 13
- Citations by year
- 2024: 1 · 2023: 2 · 2022: 2 · 2021: 1 · 2020: 2 · 2018: 5 · 2017: 5 · 2016: 10 · 2015: 4 · 2014: 5 · 2013: 7 · 2012: 6
- FWCI
- 0.61
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- International Journal of Cardiology (publishedVersion)
- PubMed (publishedVersion)
- Topics
- Health Sciences › Medicine › Cardiology and Cardiovascular Medicine › Cardiovascular Function and Risk Factors
- Health Sciences › Medicine › Cardiology and Cardiovascular Medicine › Cardiovascular Disease and Adiposity
- Health Sciences › Medicine › Endocrinology, Diabetes and Metabolism › Diabetes, Cardiovascular Risks, and Lipoproteins
- Keywords
- obesity, left ventricular diastolic dysfunction, left ventricular mass, isovolumic relaxation time, diastolic filling, early diastolic filling velocity, women
- MeSH terms
- Adult, Diastole, Female, Hemodynamics, Humans, Middle Aged, Obesity, Systole, Body Mass Index, Case-Control Studies, Hypertrophy, Left Ventricular, Ventricular Dysfunction, Left, Echocardiography, Doppler, Pulsed
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