Anticholinergic side effects of tricyclic antidepressants and their management

Antidepressants and the Muscarinic Acetylcholine Receptor

Snyder, S. H. (1977) · Archives of General Psychiatry · doi:10.1001/archpsyc.1977.01770140126014 · Cited by 428 · see citing works

Treatment Adherence

Blackwell, B. (1976) · The British Journal of Psychiatry · doi:10.1192/bjp.129.6.513 · Cited by 253 · see citing works

Effects of Antidepressant Medication on Sexual

Harrison, W. M., Rabkin, J. G., Ehrhardt, A. Α., Stewart, J. W., McGrath, P. J., Ross, D. C., & Quitkin, F. M. (1986) · Journal of Clinical Psychopharmacology · doi:10.1097/00004714-198606000-00004 · Cited by 188 · see citing works

Salivary Glands in Health and Disease.

(1977) · Annals of Internal Medicine · doi:10.7326/0003-4819-86-4-517_2 · Cited by 181 · see citing works

Drug induced ocular side effects and drug interactions

Fraunfelder, F. T. (1990) · General Pharmacology The Vascular System · doi:10.1016/0306-3623(90)90645-3 · Cited by 140 · see citing works

Salivary glands in health and disease

Rayne, J. (1976) · British Journal of Oral Surgery · doi:10.1016/0007-117x(76)90062-7 · Cited by 107 · see citing works

Antidepressants: neurochemical, behavioural and clinical perspectives

Green, A. R. (1982) · Neuroscience · doi:10.1016/0306-4522(82)90084-7 · Cited by 80 · see citing works

Management of antidepressant-induced side effects: a practical guide for the clinician.

Pollack, M. H., & Rosenbaum, J. F. (1987) · PubMed · Cited by 70 · see citing works

The use of bethanechol chloride with tricyclic antidepressants

Everett, H. C. (1975) · American Journal of Psychiatry · doi:10.1176/ajp.132.11.1202 · Cited by 69 · see citing works

Visual Effects of Pilocarpine in Glaucoma

Brown, H. S. (1976) · Archives of Ophthalmology · doi:10.1001/archopht.1976.03910040490004 · Cited by 38 · see citing works

Angle-Closure Glaucoma Induced by Miotics

Gorin, G. (1966) · American Journal of Ophthalmology · doi:10.1016/0002-9394(66)92554-2 · Cited by 37 · see citing works

Animal models used in prediction of antidepressant effects in man.

Remick, R. A., Blasberg, B., Patterson, B. D., Carmichael, R. P., & Miles, J. E. (1983) · PubMed · Cited by 35 · see citing works

The Pharmacology of the Urinary Tract

Caine, M. (1984) · Clinical practice in urology · doi:10.1007/978-1-4471-1359-1 · Cited by 31 · see citing works

Antidepressant-Induced Sexual Dysfunction in Men

Sorscher, S. M., & Dilsaver, S. C. (1986) · Journal of Clinical Psychopharmacology · doi:10.1097/00004714-198602000-00025 · Cited by 30 · see citing works

General Ophthalmology

Appleton, B. (1981) · Military Medicine · doi:10.1093/milmed/146.2.111 · Cited by 30 · see citing works

Clinical ocular pharmacology

Mindel, J. S. (1985) · Survey of Ophthalmology · doi:10.1016/0039-6257(85)90115-8 · Cited by 24 · see citing works

Drug-Induced Ocular Side Effects and Drug Interactions

Edelhauser, H. F. (1983) · American Journal of Ophthalmology · doi:10.1016/s0002-9394(14)78327-8 · Cited by 21 · see citing works

Are receptor studies useful for clinical practice?

Richelson, E. (1983) · PubMed · Cited by 20 · see citing works

Pharmacological Treatment of Non-neurogenic Voiding Dysfunction

Wein, A. J. (1984) · Clinical practice in urology · doi:10.1007/978-1-4471-1359-1_7 · Cited by 9 · see citing works

Antidepressants: which one?

Remick, R. A. (1986) · PubMed · Cited by 1 · see citing works

Adverse reactions to antidepressants

Uher, R., FARMER, A. E., Henigsberg, N., Rietschel, M., Mors, O. N., Maier, W., Kozel, D., Hauser, J., Souery, D., Placentino, A., et al. (2009) · The British Journal of Psychiatry · doi:10.1192/bjp.bp.108.061960 · Cited by 303 · see citing works

Addressing the Side Effects of Contemporary Antidepressant Drugs: A Comprehensive Review

Wang, S.-M., Han, C., Bahk, W.-M., Lee, S.-J., Patkar, A. A., Masand, P. S., & Pae, C.-U. (2018) · Chonnam Medical Journal · doi:10.4068/cmj.2018.54.2.101 · Cited by 299 · see citing works

Drug-Induced Urinary Retention

Verhamme, K. M. C., Sturkenboom, M., Stricker, B. H. C., & Bosch, J. L. H. R. (2008) · Drug Safety · doi:10.2165/00002018-200831050-00002 · Cited by 265 · see citing works

Non-hormonal Systemic Medications and Dry Eye

Wong, J. X. H., Lan, W., Ong, L. M., & Tong, L. H. T. (2011) · The Ocular Surface · doi:10.1016/s1542-0124(11)70034-9 · Cited by 97 · see citing works

Natural Products Inhibitors of Monoamine Oxidases—Potential New Drug Leads for Neuroprotection, Neurological Disorders, and Neuroblastoma

Chaurasiya, N. D., León, F., Muhammad, I., & Tekwani, B. L. (2022) · Molecules · doi:10.3390/molecules27134297 · Cited by 82 · see citing works

Anticholinergic Drug Use and Bowel Function in Nursing Home Patients

Monane, M. (1993) · Archives of Internal Medicine · doi:10.1001/archinte.153.5.633 · Cited by 82 · see citing works

Dry Eye Syndrome, Posttraumatic Stress Disorder, and Depression in an Older Male Veteran Population

Fernandez, C. A., Galor, A., Arheart, K. L., Musselman, D. L., Venincasa, V. D., Florez, H. J., & Lee, D. J. (2013) · Investigative Ophthalmology & Visual Science · doi:10.1167/iovs.13-11635 · Cited by 71 · see citing works

Overview of systematic reviews with meta-analyses on acupuncture in post-stroke cognitive impairment and depression management

Hung, C. Y.-F., Wu, X., Chung, V. C., Tang, E. C.-H., Wu, J. C., & Lau, A. Y. L. (2019) · Integrative Medicine Research · doi:10.1016/j.imr.2019.05.001 · Cited by 71 · see citing works

Pharmacological interventions for the treatment of depression in chronic obstructive pulmonary disease

Pollok, J., van Agteren, J. E., & Carson-Chahhoud, K. V. (2018) · Cochrane Database of Systematic Reviews · doi:10.1002/14651858.cd012346.pub2 · Cited by 59 · see citing works

Pharmacotherapy and the Role of Pharmacists in Rehabilitation Medicine

Yoshimura, Y., Matsumoto, A., & Momosaki, R. (2022) · Progress in Rehabilitation Medicine · doi:10.2490/prm.20220025 · Cited by 48 · see citing works

Possible association between subtypes of dry eye disease and seasonal variation

Ayaki, M., Kawashima, M., Uchino, M., Tsubota, K., & Negishi, K. (2017) · Clinical ophthalmology · doi:10.2147/opth.s148650 · Cited by 39 · see citing works

Vitamin D supplementation for irritable bowel syndrome: A systematic review and meta‐analysis

Chong, R. I. H., Yaow, C. Y. L., Loh, C. Y. L., Teoh, S. E., Masuda, Y., Ng, W. K., Lim, Y. L., & Ng, Q. X. (2022) · Journal of Gastroenterology and Hepatology · doi:10.1111/jgh.15852 · Cited by 37 · see citing works

Association Between Dry Eye Disease and Migraine Headaches in a Large Population-Based Study

Ismail, O. M., Poole, Z. B., Bierly, S. L., Buren, E. D. V., Lin, F., Meyer, J. J., & Davis, R. M. (2019) · JAMA Ophthalmology · doi:10.1001/jamaophthalmol.2019.0170 · Cited by 36 · see citing works

Medication use and dry eye symptoms: A large, hypothesis-free, population-based study in the Netherlands

Wolpert, L. E., Snieder, H., Jansonius, N. M., Utheim, T. P., Hammond, C. J., & Vehof, J. (2021) · The Ocular Surface · doi:10.1016/j.jtos.2021.06.009 · Cited by 31 · see citing works

Influence of selective serotonin reuptake inhibitors on ocular surface

Acan, D., & Kurtgoz, P. (2017) · Clinical and experimental optometry · doi:10.1111/cxo.12415 · Cited by 31 · see citing works

2025 Seoul Consensus on Clinical Practice Guidelines for Irritable Bowel Syndrome

Choi, Y., Youn, Y. H., Kang, S. J., Shin, J. E., Cho, Y. S., Jung, Y. S., Shin, S. Y., Huh, C. W., Lee, Y. J., Koo, H. S., et al. (2025) · Journal of Neurogastroenterology and Motility · doi:10.5056/jnm25007 · Cited by 33 · see citing works

Treatment of Functional Abdominal Pain With Antidepressants

Zar‐Kessler, C., Belkind‐Gerson, J., Bender, S. L., & Kuo, B. (2016) · Journal of Pediatric Gastroenterology and Nutrition · doi:10.1097/mpg.0000000000001416 · Cited by 27 · see citing works

Association of Dry Eye Disease With Dyslipidemia and Statin Use

Aldaas, K. M., Ismail, O. M., Hakim, J., Buren, E. D. V., Lin, F., Hardin, J. S., & Meyer, J. J. (2020) · American Journal of Ophthalmology · doi:10.1016/j.ajo.2020.05.007 · Cited by 24 · see citing works

Deciphering Modern Glucocorticoid Cross-pharmacology Using Ancestral Corticosteroid Receptors

Kohn, J. A., Deshpande, K., & Ortlund, E. A. (2012) · Journal of Biological Chemistry · doi:10.1074/jbc.m112.346411 · Cited by 23 · see citing works

Inhibitory Effects of Antidepressants on Acetylcholine-Induced Contractions in Isolated Guinea Pig Urinary Bladder Smooth Muscle

Uno, J., Obara, K., Suzuki, H., Miyatani, S., Chino, D., Yoshio, T., & Tanaka, Y. (2016) · Pharmacology · doi:10.1159/000452221 · Cited by 21 · see citing works

Desipramine changes salivary gland function, oral microbiota, and oral health in rats

Koller, M. M., Maeda, N., Scarpace, P. J., & Humphreys‐Beher, M. G. (2000) · European Journal of Pharmacology · doi:10.1016/s0014-2999(00)00770-6 · Cited by 20 · see citing works

Inhibition of TRPC4 channel activity in colonic myocytes by tricyclic antidepressants disrupts colonic motility causing constipation

Jeong, B., Sung, T. S., Jeon, D., Park, K. J., Jun, J. Y., So, I., & Hong, C. (2022) · Journal of Cellular and Molecular Medicine · doi:10.1111/jcmm.17348 · Cited by 18 · see citing works

The Safety of NSAIDs and Related Drugs for the Management of Acute Pain: Maximizing Benefits and Minimizing Risks

Rapoport, R. J. (1999) · Cancer Control · doi:10.1177/107327489900602s04 · Cited by 18 · see citing works

Dose-dependent constipation with higher doses of quetiapine: a case series

Raedler, T. J., Reimer, J., & Wiedemann, K. (2007) · International Clinical Psychopharmacology · doi:10.1097/yic.0b013e32805b71a3 · Cited by 18 · see citing works

Drug-induced Urinary Retention: An Analysis of a National Spontaneous Adverse Drug Reaction Reporting Database

Crisafulli, S., Cutroneo, P. M., Verhamme, K. M. C., Ferrajolo, C., Ficarra, V., Sottosanti, L., Giovanni, V. D., Spina, E., & Trifirò, G. (2021) · European Urology Focus · doi:10.1016/j.euf.2021.07.001 · Cited by 16 · see citing works

Interactive relationships of Type 2 diabetes and bipolar disorder with cognition: evidence of putative premature cognitive ageing in the UK Biobank Cohort

Ringin, E., Dunstan, D. W., McIntyre, R. S., Berk, M., Owen, N. G., Rossell, S. L., & Rheenen, T. E. V. (2022) · Neuropsychopharmacology · doi:10.1038/s41386-022-01471-6 · Cited by 16 · see citing works

In SilicoFunctional Profiling of Small Molecules and Its Applications

Sato, T., Matsuo, Y., Honma, T., & Yokoyama, S. (2008) · Journal of Medicinal Chemistry · doi:10.1021/jm800504q · Cited by 16 · see citing works

Factors affecting the prevalence, severity, and characteristics of ocular surface pain

Sánchez, V., Cohen, N. K., Felix, E. R., & Galor, A. (2022) · Expert Review of Ophthalmology · doi:10.1080/17469899.2023.2157813 · Cited by 14 · see citing works

Urological adverse drug reactions of psychotropic medication in psychiatric inpatients – A drug surveillance report from German-speaking countries

Winkler, D., Grohmann, R., Friedrich, M., Toto, S., Bleich, S., Seifert, J., Konstantinidis, A., Shariat, S. F., Kasper, S. F., & Pjrek, E. (2021) · Journal of Psychiatric Research · doi:10.1016/j.jpsychires.2021.10.026 · Cited by 12 · see citing works

Eye disorders associated with selective serotonin reuptake inhibitors: a real-world disproportionality analysis of FDA adverse event reporting system

Li, J., Zhong, R., Guo, Y., & Zhang, F. (2024) · Expert Opinion on Drug Safety · doi:10.1080/14740338.2024.2385497 · Cited by 11 · see citing works

Antidepressant-like activity and safety profile evaluation of 1H-imidazo[2,1-f]purine-2,4(3H,8H)-dione derivatives as 5-HT1A receptor partial agonists

Partyka, A., Zagórska, A., Kotańska, M., Walczak, M., Jastrzębska‐Więsek, M., Knutelska, J., Bednarski, M., Głuch‐Lutwin, M., Mordyl, B., Janiszewska, P., et al. (2020) · PLoS ONE · doi:10.1371/journal.pone.0237196 · Cited by 11 · see citing works

In Defense of Polypharmacy

Navak, D. (1998) · Psychiatric Annals · doi:10.3928/0048-5713-19980401-04 · Cited by 10 · see citing works

The 3 Ds: Depression, Dysbiosis, and Clostridiodes difficile

Boustany, A., Feuerstadt, P., & Tillotson, G. (2024) · Advances in Therapy · doi:10.1007/s12325-024-02972-0 · Cited by 7 · see citing works

Use of desipramine for the treatment of overactive bladder refractory to antimuscarinic therapy.

Hillelsohn, J. H., Rais‐Bahrami, S., Bagadiya, N. R., Kashan, M. Y., & Weiss, G. H. (2014) · Urology journal./Urology jornal. · Cited by 7 · see citing works

Medications linked to cognitive impairment in older adults.

Lepkowsky, C. M. (2016) · Practice Innovations · doi:10.1037/pri0000033 · Cited by 7 · see citing works

An analysis of submandibular salivary gland function with desipramine and age in female NIA Fischer 344 rats

Koller, M. M., Cowman, R. A., Humphreys‐Beher, M. G., & Scarpace, P. J. (2000) · Mechanisms of Ageing and Development · doi:10.1016/s0047-6374(00)00176-7 · Cited by 7 · see citing works

Desipramine desensitizes β-adrenergic signal transduction in rat salivary glands

Scarpace, P. J., Koller, M. M., & Rajakumar, G. (1992) · Neuropharmacology · doi:10.1016/0028-3908(92)90060-3 · Cited by 7 · see citing works

Pharmacological Mechanism and Drug Research Prospects of Ginsenoside Rb1 as an Antidepressant

Zhuang, S., Shi, F., Cannella, N., Ubaldi, M., Ciccocioppo, R., Li, H., & Qin, D. (2025) · Antioxidants · doi:10.3390/antiox14020238 · Cited by 8 · see citing works

A review of antidepressant-induced urinary hesitancy: a focus on levomilnacipran ER including two case presentations(5633)

Asnis, G. M., Caneva, E., & Henderson, M. A. (2016) · Expert Opinion on Drug Safety · doi:10.1517/14740338.2016.1164138 · Cited by 4 · see citing works

Drug Safety in Episodic Migraine Management in Adults. Part 2: Preventive Treatments

Chua, A. L., Mehla, S., & Orlova, Y. Y. (2022) · Current Pain and Headache Reports · doi:10.1007/s11916-022-01051-9 · Cited by 3 · see citing works

Recent Developments in the Management of Post- Traumatic Pain

Recla, J. M. (2010) · Cited by 2 · see citing works

Review of Current Clinical Options for the Management of Behavioral and Psychological Symptoms of Dementia

Malena, K., Rao, S., & Mosler, C. (2024) · The Senior Care Pharmacist · doi:10.4140/tcp.n.2024.300 · Cited by 2 · see citing works

Effects of Escitalopram on the Functional Neural Circuits in an Animal Model of Adolescent Depression

Oh, S. J., Lee, N., Nam, K. R., Kang, K. J., Han, S. J., & Choi, J. Y. (2023) · Molecular Imaging and Biology · doi:10.1007/s11307-023-01825-6 · Cited by 2 · see citing works

Psychopathological Problems in Chronic Obstructive Pulmonary Disease (C.O.P.D.): An Holistic “Mind-Body” Comprehension

Gatti, G., Giordano, M., & Mollica, C. (2023) · Springer eBooks · doi:10.1007/978-3-031-27968-3_13 · Cited by 1 · see citing works

Catastrophic Drug-Drug Interactions in Psychopharmacology

Carlo, A. D., & Alpert, J. E. (2016) · Psychiatric Annals · doi:10.3928/00485713-20160623-01 · Cited by 1 · see citing works

Drug-Drug Interactions at Receptors and Other Active Sites

Schorderet, M., & Ferrero, J. D. (1996) · Handbook of experimental pharmacology · doi:10.1007/978-3-642-61015-8_7 · Cited by 1 · see citing works

Understanding therapies selected for managing pain associated with spinal cord injuries

Surmanski, A. A. (2018) · University of Western Ontario Medical Journal · doi:10.5206/uwomj.v87i1.1805

Investigation of Post-Mortem Redistribution Using In Vitro Models

Lomas, E. C. (2018) · University of Huddersfield Repository (University of Huddersfield)

Sleep Disorders

Diaz, N. A. (2018) · Springer eBooks · doi:10.1007/978-3-319-73078-3_18

Antidepressant drugs

Elphick, M. (1991) · Side effects of drugs annual · doi:10.1016/s0378-6080(05)80305-8

Alprazolam, um Modulador Alostérico para os Recetores GABAA

Azuaje, J. I. (2023) · Boletim da Sociedade Portuguesa de Química · doi:10.52590/m3.p707.a30002709

Question

Salzman, C. (2025) · Journal of Clinical Psychopharmacology · doi:10.1097/jcp.0000000000001991

Tricyclic antidepressants for treatment-resistant depression

Bobo, W. V., & Richelson, E. (2022) · Elsevier eBooks · doi:10.1016/b978-0-12-824067-0.00008-6

Pharmacotherapy

Sunzeri, F. (2026) · Springer eBooks · doi:10.1007/978-3-032-14465-2_16

Management of Adverse Drug Effects for Adjunctive Analgesics

Lewis, S. J., Sjoquist, L. K., & Churchwell, M. D. (2026) · Springer eBooks · doi:10.1007/978-3-032-21675-5_19

Investigação do envolvimento de subtipos de adrenoceptores α1 no efeito anti-imobilidade da imipramina no teste de suspensão pela cauda

Ribeiro, C. A. D. S. (2015) · Aleph UCLA Undergraduate Research Journal for the Humanities and Social Sciences

[Side effects and its countermeasures of antidepressant].

Ueda, N., & Nakamura, J. (2001) · PubMed · Cited by 1 · see citing works

Reactions to Antidepressants: Tricyclic and Tetracyclic

Tornatore, F. L., Sramek, J. J., Okeya, B. L., & Pi, E. H. (1987) · Springer eBooks · doi:10.1007/978-1-4684-5412-3_2

The use of bethanechol chloride with tricyclic antidepressants

Everett, H. C. (1975) · American Journal of Psychiatry · doi:10.1176/ajp.132.11.1202 · Cited by 69 · see citing works

Rampant dental caries in the treatment of depression.

Bassuk, E. L., & Schoonover, S. C. (1978) · PubMed · Cited by 19 · see citing works

[Anticholinergic delirium. Adverse effect in treatment with tricyclic antidepressive agents].

Seier, L., & Solheim, D. M. (1987) · PubMed · Cited by 1 · see citing works