The DOI matches its Crossref record; 1 of the 1 references it cites were found in a registry or an index.
Non-steroidal anti-inflammatory drugs and spinal nociceptive processing
Abstract
Non-steroidal anti-inflammatory drugs have a direct action on spinal nociceptive processing in vivo with a relative order of potency which correlates with their capacity as inhibitors of cyclooxygenase activity. However, recent clinical surveys and new in vivo evidence strongly suggest that for some of these agents, centrally mediated analgesia may also be achieved by additional mechanisms, which are independent of prostaglandin synthesis inhibition. In this review we explore the likelihood for such mechanisms following an extensive survey of existing data. The implications of these mechanisms are discussed in the light of our current understanding of spinal nociceptive processing.
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Citations
Cites
Antinociceptive effect of paracetamol in rats is partly dependent on spinal serotonergic systems
Tjølsen, A., Lund, A., & Hole, K. (1991) · European Journal of Pharmacology · doi:10.1016/0014-2999(91)90036-p · Cited by 163 · cited 2×
“The activation of the descending serotonergic inhibitory pathway has been proposed as a mechanism to account for the analgesic effect of some non-acidic NSAIDs, including acetaminophen (Tjolsen et al. 1991).”
Background
Cited by
The induction of pain: an integrative review
Millan, M. J. (1999) · Progress in Neurobiology · doi:10.1016/s0301-0082(98)00048-3 · Cited by 1,774
Dehorning and disbudding distress and its alleviation in calves
Stafford, K. J., & Mellor, D. J. (2005) · The Veterinary Journal · doi:10.1016/j.tvjl.2004.02.005 · Cited by 296
Postoperative Analgesic Effects of Celecoxib or Rofecoxib After Spinal Fusion Surgery
Reuben, S. S., & Connelly, N. R. (2000) · Anesthesia & Analgesia · doi:10.1097/00000539-200011000-00032 · Cited by 270
RetractedAcetaminophen Inhibits Spinal Prostaglandin E2Release after Peripheral Noxious Stimulation
Muth-Selbach, U. S., Tegeder, I., Brune, K., & Geisslinger, G. (1999) · Anesthesiology · doi:10.1097/00000542-199907000-00032 · Cited by 142
The efficacy of combination analgesic therapy in relieving dental pain
MEHLISCH, D. R. (2002) · The Journal of the American Dental Association · doi:10.14219/jada.archive.2002.0300 · Cited by 141
Metadata
- Authors
- McCormack, K.
- Venue
- Pain
- Published
- 1994-10
- Volume
- 59
- Issue
- 1
- Pages
- 9-43
- ISSN
- 0304-3959 (ISSN-L)
- OpenAlex
- W2049481868
- Cited by
- 263
- References
- 1
- FWCI
- 10.25
- Type
- journal article
- Language
- en
- Open access
- closed
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- McCormack, K. (1994). Non-steroidal anti-inflammatory drugs and spinal nociceptive processing. Pain. https://doi.org/10.1016/0304-3959(94)90045-0
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Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
