A possible role for the species peroxonitrite in intrification
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Nitric oxide reacts with superoxide at a high rate constant to give peroxynitrite, which can decompose spontaneously to yield nitrogen dioxide and hydroxyl radicals.
“However, nitric oxide reacts with superoxide at a high rate constant to give peroxynitrite (ONOO−), able to decompose spontaneously to yield nitrogen dioxide (•NO2) and hydroxyl radicals [2].”
From Protein oxidation - Formation mechanisms, detection and relevance as biomarkers in human diseases (2021) · cites this paper as [2]
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Nitric Oxide and Peroxynitrite in Health and Disease
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Protein oxidation - Formation mechanisms, detection and relevance as biomarkers in human diseases
Kehm, R., Baldensperger, T., Raupbach, J., & Höhn, A. (2021) · Redox Biology · doi:10.1016/j.redox.2021.101901 · Cited by 348 · see citing works
“However, nitric oxide reacts with superoxide at a high rate constant to give peroxynitrite (ONOO), able to decompose spontaneously to yield nitrogen dioxide (NO2) and hydroxyl radicals [2].”
BackgroundReaction of No With O2−. Implications for the Action of Endothelium-Derived Relaxing Factor (EDRF)
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Multi-Target Antioxidant Potential of Tricin Against Parkinson’s Disease-Linked Oxidative Stress
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- Authors
- Hughes, M. N., & Nicklin, H. G.
- Affiliations
- University of London (GB)
- ORCID
- Hughes, M.N.
- Venue
- Biochimica et Biophysica Acta (BBA) - General Subjects
- Publisher
- Elsevier BV
- Published
- 1970-12
- Volume
- 222
- Issue
- 3
- Pages
- 660-661
- ISSN
- 0304-4165 (ISSN-L)
- OpenAlex
- W2052460130
- Cited by
- 17
- References
- 6
- Citations by year
- 2026: 1 · 2021: 1 · 2017: 1 · 2015: 1 · 2014: 1
- FWCI
- 0.23
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- Biochimica et Biophysica Acta (BBA) - General Subjects (publishedVersion)
- PubMed (publishedVersion)
- Topics
- Life Sciences › Biochemistry, Genetics and Molecular Biology › Molecular Biology › Redox biology and oxidative stress
- Health Sciences › Medicine › Physiology › Nitric Oxide and Endothelin Effects
- Life Sciences › Immunology and Microbiology › Immunology › Neutrophil, Myeloperoxidase and Oxidative Mechanisms
- Keywords
- intracellular signaling, reactive oxygen species, nitric oxide, hydrogen peroxide
- MeSH terms
- Alkalies, Ammonia, Binding Sites, Hydrogen-Ion Concentration, Hydroxylamines, Nitrites, Nitrosomonas, Oxidation-Reduction, Oxidoreductases
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