The DOI matches its Crossref record.
Late effects of radiation therapy in the head and neck region
Open accessAbstract
The head and neck region is composed of numerous structures, each with an inherent response to radiation that is largely governed by the presence or absence of mucosa, salivary glands, or specialized organs within that site. Irradiated mucocutaneous tissues demonstrate increased vascular permeability that leads to fibrin deposition, subsequent collagen formation, and eventual fibrosis. Irradiated salivary tissue degenerates after relatively small doses, leading to markedly diminished salivary output. This, in turn, effects the teeth by promoting dental decay which, in turn, effects the integrity of the mandible. Details of these changes are presented, including their pathophysiology, clinical syndromes, and potential treatment.
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Cited by
Stewart, F. A., Akleyev, A. V., Hauer-Jensen, M., Hendry, J. H., Kleiman, N. J., MacVittie, T. J., Aleman, B. M., Edgar, A. B., Mabuchi, K., Muirhead, C. R., et al. (2012) · Annals of the ICRP · doi:10.1016/j.icrp.2012.02.001 · Cited by 1,604
Lee, N., Xia, P., Quivey, J. M., Sultanem, K., Poon, I., Akazawa, C., Akazawa, P., Weinberg, V., & Fu, K. K. (2002) · International Journal of Radiation Oncology*Biology*Physics · doi:10.1016/s0360-3016(02)02724-4 · Cited by 986
Self-citationEisbruch, A., Ten Haken, R. K., Kim, H. M., Marsh, L. H., & Ship, J. A. (1999) · International Journal of Radiation Oncology*Biology*Physics · doi:10.1016/s0360-3016(99)00247-3 · Cited by 922
Prevention and Treatment of Dysphagia and Aspiration After Chemoradiation for Head and Neck Cancer
Rosenthal, D. I., Lewin, J. S., & Eisbruch, A. (2006) · Journal of Clinical Oncology · doi:10.1200/jco.2006.06.0079 · Cited by 401
P revention and T reatment of the C onsequences of H ead and N eck R adiotherapy
Vissink, A., Burlage, F. R., Spijkervet, F. K. L., Jansma, J., & Coppes, R. P. (2003) · Critical Reviews in Oral Biology & Medicine · doi:10.1177/154411130301400306 · Cited by 384
Metadata
- Authors
- Cooper, J. S., Fu, K., Marks, J., & Silverman, S.
- Venue
- International Journal of Radiation Oncology*Biology*Physics
- Publisher
- Elsevier BV
- Published
- 1995-03
- Volume
- 31
- Issue
- 5
- Pages
- 1141-1164
- ISSN
- 0360-3016 (ISSN-L)
- OpenAlex
- W2036198544
- Cited by
- 453
- References
- 0
- FWCI
- 6.43
- Type
- journal article
- Language
- en
- Open access
- hybrid
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- The paper
- Cooper, J. S., Fu, K., Marks, J., & Silverman, S. (1995). Late effects of radiation therapy in the head and neck region. International Journal of Radiation Oncology*Biology*Physics. https://doi.org/10.1016/0360-3016(94)00421-g
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Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
