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Cited by 384

The DOI matches its Crossref record; 78 of the 78 references it cites were found in a registry or an index.

P revention and T reatment of the C onsequences of H ead and N eck R adiotherapy

Open access
Vissink, A., Burlage, F.R., Spijkervet, F.K.L., Jansma, J., Coppes, R.P.·2003·Critical Reviews in Oral Biology & Medicine

Abstract

The location of the primary tumor or lymph node metastases dictates the inclusion of the oral cavity, salivary glands, and jaws in the radiation treatment portals for patients who have head and neck cancer. The clinical sequelae of the radiation treatment include mucositis, hyposalivation, loss of taste, osteoradionecrosis, radiation caries, and trismus. These sequelae may be dose-limiting and have a tremendous effect on the patient’s quality of life. Most treatment protocols to prevent these sequelae are still based on clinical experience, but alternatives based on fundamental basic and clinical research are becoming more and more available. Many of these alternatives either need further study before they can be incorporated into the protocols commonly used to prevent and treat the radiation-related oral sequelae or await implementation of these protocols. In this review, the various possibilities for prevention and/or treatment of radiation-induced changes in healthy oral tissues and their consequences are discussed.

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Crossref · 10.1177/154411130301400306

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Metadata

Authors
Vissink, A., Burlage, F. R., Spijkervet, F. K. L., Jansma, J., & Coppes, R. P.
Venue
Critical Reviews in Oral Biology & Medicine
Published
2003-05
Volume
14
Issue
3
Pages
213-225
ISSN
  • 1045-4411 (ISSN-L)
  • 1544-1113
OpenAlex
W2161434409
Cited by
384
References
78
FWCI
12.52
Type
journal article
Language
en
Open access
green

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The paper
Vissink, A., Burlage, F. R., Spijkervet, F. K. L., Jansma, J., & Coppes, R. P. (2003). P revention and T reatment of the C onsequences of H ead and N eck R adiotherapy. Critical Reviews in Oral Biology & Medicine. https://doi.org/10.1177/154411130301400306

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