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Concurrent and simultaneous use of alcohol with cocaine: results of national survey
Abstract
The purpose of the present study was to determine the prevalence of the concurrent and simultaneous use of alcohol and cocaine in the general population and to examine differences in these rates between important sociodemographic subgroups. The results indicated that a sizable proportion of Americans were engaged in both substance use patterns. The population estimate for simultaneous use of both substances (i.e., simultaneously or on the same occasion) was approximately 4 million for the month preceding the interview, rising to approximately 9 million when the past year timeframe was considered. Corresponding figures for the concurrent use of alcohol and cocaine (i.e., use of both substances during the same time period) were approximately 5 million during the past month and 12 million during the past year. The extent of each substance use practice varied as a function of sociodemographic factors. Implications of these findings are discussed in terms of the need for age-sex-ethnic-specific prevention strategies. The need for future analytic epidemiologic research to determine the precise relationship between dose, frequency and duration of concurrent and simultaneous use and each adverse consequence is emphasized. The need for longitudinal research in the general population is also highlighted.
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“Numerous studies have shown that the majority of patients who abuse cocaine also abuse alcohol, ranging from 50% to 90% [53], [54], [55], [56], [57], [58].”
From Disulfiram Efficacy in the Treatment of Alcohol Dependence: A Meta-Analysis (2014) · cites this paper as [55]
Citations
Cites
Statistical Methods for Rates and Proportions
Fleiss, J. L., Levin, B., & Paik, M. C. (2003) · Wiley Series in Probability and Statistics · doi:10.1002/0471445428 · Cited by 18,646
Statistical Methods for Rates and Proportions.
Everitt, B. S., & Fleiss, J. L. (1981) · Biometrics · doi:10.2307/2530193 · Cited by 9,034
National Household Survey on Drug Abuse: Population Estimates 1998
(1999) · PsycEXTRA Dataset · doi:10.1037/e438212005-001 · Cited by 400
National Household Survey on Drug Abuse: Main Findings 1998
(2000) · PsycEXTRA Dataset · doi:10.1037/e442572005-001 · Cited by 396
Self-report methods of estimating drug use: Meeting current challenges to validity.
Kozel, N. J., Rouse, B. A., & Richards, L. M. (1985) · PubMed · Cited by 223
Self-report methods of estimating drug use: Meeting current challenges to validity.
(1985) · PubMed · Cited by 180
Cocaine use in America: epidemiologic and clinical perspectives.
(1985) · PubMed · Cited by 128
Neuropsychological assessment substance abusers: Review and recommendations
Miller, L. (1985) · Journal of Substance Abuse Treatment · doi:10.1016/0740-5472(85)90017-0 · Cited by 120
Validation of self-report: the research record
Harrell, A. V. (1985) · PsycEXTRA Dataset · doi:10.1037/e496952006-003 · Cited by 70
Prevention of Acetaminophen and Cocaine Hepatotoxicity in Mice by Cimetidine Treatment
Peterson, F. J., Knodell, R. G., Lindemann, N. J., & Steele, N. M. (1983) · Gastroenterology · doi:10.1016/s0016-5085(83)80238-8 · Cited by 51
Research works printed but not linked: 2
- Hoyumpa, 1981, Viewpoints on Digestive Diseases, 13, 1
- Kroll, 1986, Hosp. Comm. Psychiat., 37, 283
Cited by
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Meehan, S. M., & Schechter, M. D. (1995) · Alcohol · doi:10.1016/0741-8329(95)00022-j · Cited by 11
Integration of Generalized Vulnerability to Drug and Alcohol Addiction
Miller, N. S., Guttman, J. C., & Chawla, S. (1997) · Journal of Addictive Diseases · doi:10.1080/10550889709511140 · Cited by 10
Bifone, A., Gozzi, A., Cippitelli, A., Matzeu, A., Domi, E., Li, H., Scuppa, G., Cannella, N., Ubaldi, M., Weiss, F., et al. (2018) · Addiction Biology · doi:10.1111/adb.12671 · Cited by 10
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Пирожков, С. В., Eskelson, C. D., & WATSON, R. R. (1992) · Alcoholism Clinical and Experimental Research · doi:10.1111/j.1530-0277.1992.tb01891.x · Cited by 10
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Grathwohl, C., Dadmarz, M., & Vogel, W. H. (2001) · Pharmacology · doi:10.1159/000056128 · Cited by 10
Developmental immunotoxicity of cocaine and ethanol in postnatal Lewis rats
Figliomeni, M. L., & Turkall, R. M. (1997) · Immunopharmacology · doi:10.1016/s0162-3109(96)00153-1 · Cited by 10
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Parker, R. B., Laizure, S. C., Williams, C. L., Mandrell, T. D., & Lima, J. J. (1997) · Life Sciences · doi:10.1016/s0024-3205(97)01115-6 · Cited by 10
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Behavior and Drug Measurements in Long–Evans and Sprague–Dawley Rats After Ethanol–Cocaine Exposure
Horowitz, J. M., Bhatti, E., Devi, B. G., & Torres, G. (1999) · Pharmacology Biochemistry and Behavior · doi:10.1016/s0091-3057(98)00160-9 · Cited by 9
Effects of repeated cocaine administration on alcohol consumption.
Uemura, K., Li, Y. J., Ohbora, Y., Fujimiya, T., & Komura, S. (1998) · Journal of Studies on Alcohol · doi:10.15288/jsa.1998.59.115 · Cited by 9
Borders, T. F., & Booth, B. M. (2011) · Addictive Behaviors · doi:10.1016/j.addbeh.2011.11.003 · Cited by 9
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Horowitz, J. M., & Torres, G. (1999) · Addiction Biology · doi:10.1080/13556219971632 · Cited by 9
Alcohol in Suicide Attempts and Completions
Gossop, M. (2005) · Psychiatric Annals · doi:10.3928/00485713-20050601-08 · Cited by 9
Effect of acute ethanol and cocaine administration on gestation days 14–17 in mice
Salo, A. L., Randall, C. L., & Becker, H. C. (1996) · Alcohol · doi:10.1016/0741-8329(96)00026-2 · Cited by 9
Prinssen, E. P. M., Kleven, M. S., & Koek, W. (1996) · Psychopharmacology · doi:10.1007/bf02247434 · Cited by 9
Barron, S. (1996) · Pharmacology Biochemistry and Behavior · doi:10.1016/0091-3057(95)00178-6 · Cited by 9
Tryhus, A. M., Epperly, P. M., Davenport, A. T., Galbo, L. K., & Czoty, P. W. (2021) · Drug and Alcohol Dependence · doi:10.1016/j.drugalcdep.2021.108707 · Cited by 8
Addiction à la cocaïne : un facteur de risque de suicide ?
Petit, A., Reynaud, M., Lejoyeux, M., Coscas, S., & Karila, L. (2012) · La Presse Médicale · doi:10.1016/j.lpm.2011.12.006 · Cited by 8
Segar, T. M., Klebaur, J. E., Bardo, M. T., & Barron, S. (1999) · Alcoholism Clinical and Experimental Research · doi:10.1097/00000374-199901000-00002 · Cited by 8
Salo, A. L., Randall, C. L., Becker, H. C., & Patrick, K. S. (1995) · Neurotoxicology and Teratology · doi:10.1016/0892-0362(95)00018-m · Cited by 8
Moriya, F., Hashimoto, Y., & Ishizu, H. (1995) · Forensic Science International · doi:10.1016/0379-0738(95)01821-2 · Cited by 8
Human Liver Cocaine Carboxylesterases
BOSRON, W. F., Dean, R. A., Brzezinski, M. R., & Pindel, E. V. (1997) · PsycEXTRA Dataset · doi:10.1037/e495572006-004 · Cited by 8
John, W. S., & Nader, M. A. (2016) · Drug and Alcohol Dependence · doi:10.1016/j.drugalcdep.2016.11.002 · Cited by 7
Nardi, D. A. (1997) · Issues in Mental Health Nursing · doi:10.3109/01612849709010329 · Cited by 7
Sable, H. J. K., White, S. L., & Steinpreis, R. E. (2004) · Alcohol · doi:10.1016/j.alcohol.2004.04.004 · Cited by 7
Barbieri, E. J., Digregorio, G. J., Ferko, A. P., & Ruch, E. K. (1994) · Journal of Analytical Toxicology · doi:10.1093/jat/18.1.60 · Cited by 7
Cardiotoxic Properties of Cocaine: Studies With Positron Emission Tomography
Volkow, N. D., Fowler, J. S., & Ding, Y. ‐. (1996) · PsycEXTRA Dataset · doi:10.1037/e495672006-009 · Cited by 7
The effect of ethanol exposure on cocaine toxicity in rat hepatocytes
Figliomeni, M. L., & Abdel‐Rahman, M. S. (1997) · Toxicology in Vitro · doi:10.1016/s0887-2333(97)00029-5 · Cited by 6
Does ethanol enhance cocaine toxicity?
Karch, S. B., Stephens, B. G., & Tseng, A. (1999) · Journal of Clinical Forensic Medicine · doi:10.1016/s1353-1131(99)90171-2 · Cited by 6
Fischman, M. W., & Johanson, C. E. (1996) · Handbook of experimental pharmacology · doi:10.1007/978-3-642-60963-3_4 · Cited by 6
Immunotoxicity of Cocaethylene
Chiappelli, F., Kung, M. A., Villanueva, P., Lee, P. J., Frost, P., & Prieto, N. (1995) · Immunopharmacology and Immunotoxicology · doi:10.3109/08923979509019759 · Cited by 6
Ma, H., Lee, G., Park, J.-S., Lee, J., Wang, F., Ma, Y., Sui, G.-Y., Rustamov, N., Kim, S. H., Jung, Y., et al. (2024) · Cell Biology and Toxicology · doi:10.1007/s10565-024-09901-5 · Cited by 5
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Østergaard, J., Østergaard, S. V., & Fletcher, A. (2016) · Contemporary Drug Problems · doi:10.1177/0091450916661372 · Cited by 5
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Briscoe, R. J., Baird, T. J., Lerner, M. R., Brackett, D. J., & Gauvin, D. V. (1999) · Alcohol · doi:10.1016/s0741-8329(99)00029-4 · Cited by 5
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Wilson, D. M., Ferko, A. P., Barbieri, E. J., Digregorio, G. J., Bobyock, E., & McMichael, R. F. (1997) · Pharmacology Biochemistry and Behavior · doi:10.1016/s0091-3057(96)00130-x · Cited by 3
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Cheng, T. O. (1999) · Heart & Lung · doi:10.1016/s0147-9563(99)70001-4 · Cited by 3
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Grayburn, P. A., & Eichhorn, E. J. (2007) · Springer eBooks · doi:10.1007/978-1-84628-715-2_113 · Cited by 2
Rush, C. R., Roll, J. M., & Higgins, S. T. (1998) · Elsevier eBooks · doi:10.1016/b978-012347360-8/50012-4 · Cited by 2
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Linari, G., Antonilli, L., Nencini, P., & Nucerito, V. (2001) · Pharmacological Research · doi:10.1006/phrs.2001.0834 · Cited by 2
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Briscoe, R. J., & Gauvin, D. V. (1999) · Alcohol · doi:10.1016/s0741-8329(98)00032-9 · Cited by 2
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Volkow, N. D., Fowler, J. S., Wang, G., & Shreeve, W. W. (2003) · Springer eBooks · doi:10.1007/978-3-642-55539-8_18 · Cited by 2
Sevarino, K. A., & Shelby, B. C. (2015) · Wiley eBooks · doi:10.1002/9781118753378.ch80 · Cited by 1
Higgins, S. T., & Bickel, W. K. (1993) · Psychiatric Services · doi:10.1176/ps.44.10.1007-a · Cited by 1
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Jora, N. P. (2014) · doi:10.11606/t.22.2014.tde-07012015-140041 · Cited by 1
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de Wit, H. (2026) · American Journal of Psychiatry · doi:10.1176/appi.ajp.20251138 · Cited by 1
Kunin, D. (1998) · Spectrum Research Repository (Concordia University)
Disposition kinetics of cocaine in rats
Sukbuntherng, J. (1997) · UA Campus Repository (The University of Arizona)
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Ange, R. I. A. L., & Illis, L. D. A. H. (2001)
Polyconsommation : une pratique peu répandue en population générale
Beck, F., Legleye, S., & Spilka, S. (2007) · HAL
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Lima, I. S. P. (2009) · Portuguese National Funding Agency for Science, Research and Technology (RCAAP Project by FCT)
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Neto, A. G. D. C., Rameh-de-Albuquerque, R. C., de Medeiros, P. F. P., & Uchôa, R. (2019) · Elsevier eBooks · doi:10.1016/b978-0-12-813125-1.00055-6
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Prete, J. N., Collier, M. A., Epperly, P. M., & Czoty, P. W. (2024) · Drug and Alcohol Dependence · doi:10.1016/j.drugalcdep.2024.111347
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Paula, G. R., Rebeca, F. G., Enma, E. H., Sonia, G. L., Mónica, B. A., & Pilar, A. R. M. (2023) · Revista sanitaria de investigación. · doi:10.34896/rsi.2023.25.41.001
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Volkow, N. D., Fowler, J. S., & Wang, G. (2000) · Springer eBooks · doi:10.1007/978-3-642-59627-8_22
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Poet, T. S. (1991) · UA Campus Repository (The University of Arizona)
Metadata
- Authors
- Grant, B. F., & Harford, T. C.
- Affiliations
- National Institute on Alcohol Abuse and Alcoholism (US)
- Venue
- Drug and Alcohol Dependence
- Publisher
- Elsevier BV
- Published
- 1990-02
- Volume
- 25
- Issue
- 1
- Pages
- 97-104
- ISSN
- 0376-8716 (ISSN-L)
- OpenAlex
- W2096948351
- Cited by
- 275
- References
- 15
- Citations by year
- 2026: 1 · 2025: 1 · 2024: 3 · 2023: 3 · 2022: 6 · 2021: 2 · 2020: 2 · 2019: 2 · 2018: 3 · 2017: 3 · 2016: 5 · 2015: 7 · 2014: 3 · 2013: 1 · 2012: 7
- FWCI
- 14.16
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- Drug and Alcohol Dependence (publishedVersion)
- PubMed (publishedVersion)
- Topics
- Health Sciences › Medicine › Epidemiology › Substance Abuse Treatment and Outcomes
- Health Sciences › Medicine › Public Health, Environmental and Occupational Health › Youth, Drugs, and Violence
- Health Sciences › Medicine › Epidemiology › HIV, Drug Use, Sexual Risk
- Keywords
- concurrent substance use, prevalence, sociodemographic differences, substance use prevention, general population
- MeSH terms
- Adolescent, Adult, Alcoholism, Cocaine, Cross-Sectional Studies, Female, Humans, Male, United States, Incidence, Substance-Related Disorders
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