Cited by 187Aortic aneurysm repair treatmentsAortic Disease and Treatment ApproachesCardiac, Anesthesia and Surgical Outcomes

Late survival after abdominal aortic aneurysm repair: Influence of coronary artery disease

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Hollier, L.H., Plate, G., O'Brien, P.C., Kazmier, F.J., Gloviczki, P., Pairolero, P.C., Cherry, K.J.·1984·Journal of Vascular Surgery

Abstract

To evaluate long-term survival in relation to preoperative risk factors, we reviewed 1112 patients undergoing abdominal aortic aneurysm (AAA) repair from 1970 to 1975. A 6-to 12-year follow-up was obtained on 1087 patients (97.7%) by chart review, death certificates, autopsy reports, and questionnaires returned by patients and referring physicians. Preoperatively 24% of patients had a history of prior myocardial infarction, 19.9% had a history of angina, and 40.4% were hypertensive. Emergency operation for ruptured aneurysm was performed in 6.5% and for expanding aneurysm in 3.4% of patients. The survival rate at 5 years was 67.5% and at 10 years was 40.7%. Cardiac-related problems were the most frequent cause of death (38%); 23% died of myocardial infarction and 15% from other heart disease or sudden death. Other causes included neoplasm (14.6%), other ruptured aneurysm (8.2%), and stroke (6.8%). Cause of death was unknown in 19.6%. A significant correlation of reduced survival time was noted in patients with advanced age and those with evidence of heart disease or hypertension. For patients without preoperative evidence of heart disease or hypertension, the 5-year mortality rate from myocardial infarction was 3.7%, compared with 11.7% for those with a positive history of hypertension and heart disease (p = 0.0001). For patients with no preoperative evidence of hypertension or heart disease, the length of survival after AAA repair was the same as that expected for the general population with the same age and sex composition. This study supports the contention that coronary angiography and prophylactic coronary bypass grafting should be performed selectively. Decisions regarding the need for coronary revascularization should be based on symptoms, noninvasive testing, and selective coronary angiography because aneurysmal disease alone is not shown in this study to increase the risk of death from myocardial disease. For patients with clinical findings of coronary artery disease, an aggressive diagnostic approach appears to be justified.

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Research works printed but not linked: 5

  1. Crawford ES, SalWa AS, Bagg III JW, et al. Infrarenal ab- dominal aortic aneurysm: Factors influencing survival after operation performed over a 25-year period, Ann Surg 1981; 193:699-709.
  2. Thompson JE, Hollier LH, Patman RD, et al. Surgical man- agement of abdominal aortic aneurysms: Factors influencing mortality and morbidity: A 20-year experience. Ann Surg 1975; 181:654-61.
  3. European Coronary Artery Surgery Group. PrOspective ran- domized study of coronary artery bypass surgery in stable angina pectoris. Lancet 1980; 2:491-5.
  4. Kaplan EL, Meier P. Non-parametric estimation from in- complete observations. J Am Statistical Assoc 1958; 53: 457-81.
  5. O'Bricn PC. A non-parametric test for association with cen- sored data. Biometrics 1978; 34:24340.

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Authors
Hollier, L. H., Plate, G., O'Brien, P. C., Kazmier, F. J., Gloviczki, P., Pairolero, P. C., & Cherry, K. J.
Affiliations
Mayo Clinic (US)
Venue
Journal of Vascular Surgery
Publisher
Elsevier BV
Published
1984-03
Volume
1
Issue
2
Pages
290-299
ISSN
0741-5214 (ISSN-L)
OpenAlex
W2064437386
Cited by
187
References
28
Citations by year
2026: 1 · 2021: 1 · 2019: 2 · 2018: 1 · 2017: 1 · 2016: 3 · 2015: 5 · 2014: 4 · 2013: 1 · 2012: 3
FWCI
7.93
Type
journal article
Language
en
Open access
Locations
  • Journal of Vascular Surgery (publishedVersion)
  • PubMed (publishedVersion)
Topics
  • Health Sciences › Medicine › Pulmonary and Respiratory Medicine › Aortic aneurysm repair treatments
  • Health Sciences › Medicine › Pulmonary and Respiratory Medicine › Aortic Disease and Treatment Approaches
  • Health Sciences › Medicine › Cardiology and Cardiovascular Medicine › Cardiac, Anesthesia and Surgical Outcomes
Keywords
abdominal aortic aneurysm repair, long-term survival, coronary artery disease, myocardial infarction, hypertension, preoperative risk factors, coronary angiography, coronary artery bypass grafting, coronary revascularization, causes of death, aneurysm rupture, age and mortality
MeSH terms
Aged, Angina Pectoris, Aorta, Abdominal, Aortic Aneurysm, Coronary Disease, Female, Humans, Hypertension, Male, Middle Aged, Myocardial Infarction, Risk, Rupture

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