Cited by 66Peripheral Artery Disease ManagementVascular Procedures and ComplicationsRenal and Vascular Pathologies

Race as a risk factor in the severity of infragenicular occlusive disease: Study of an urban hospital patient population

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Sidawy, Anton N., Schweitzer, Eugene J., Neville, Richard F., Alexander, E.Pendelton, Temeck, Barbara K., Curry, Kathleen M.·1990·Journal of Vascular Surgery

Abstract

We retrospectively studied the arteriograms of 135 men admitted for evaluation of lower extremity ischemia to examine whether race influences the severity of infragenicular occlusive disease. The scoring system prepared by the Ad Hoc Committee on Reporting Standards for the Society for Vascular Surgery and the International Society for Cardiovascular Surgery was used to grade the severity of stenosis in each of the upper, middle, and lower thirds of the anterior and posterior tibial and peroneal arteries (collectively called "infragenicular" arteries). The patients were divided into two groups: 83 blacks (140 arteriogram limbs) and 52 whites (87 arteriogram limbs). Disease severity scores between the groups were compared, and the existence of five known risk factors for atherosclerosis were considered for poststratification adjustment. Results showed that higher disease scores, indicating more severe disease, were found in the black population in every segment of the infragenicular arteries. The mean (+/- SE) score for all the infragenicular segments in blacks was significantly higher than that in the whites (2.08 +/- 0.05 vs 1.57 +/- 0.06, p less than 0.001). The black and white groups were comparable in terms of age (65.2 vs 64.6 years), prevalence of diabetes (20% vs 25%), smoking history (93% vs 90%), and hypercholesterolemia (51% vs 63%). Hypertension was more prevalent among the black patients (51% vs 27%, p less than 0.001). When only the non-hypertensive patients in both groups were considered, however; the mean severity score was still significantly higher in blacks (2.10 +/- 0.06 vs 1.42 +/- 0.06, p less than 0.001).(ABSTRACT TRUNCATED AT 250 WORDS)

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  1. McGarry, 1985, Cerebral atherosclerosis in New Orleans, Lab Invest, 52, 533

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Authors
Sidawy, A. N., Schweitzer, E. J., Neville, R. F., Alexander, E. P., Temeck, B. K., & Curry, K. M.
Affiliations
Georgetown University (US)
Venue
Journal of Vascular Surgery
Publisher
Elsevier BV
Published
1990-04
Volume
11
Issue
4
Pages
536-543
ISSN
0741-5214 (ISSN-L)
OpenAlex
W2027421295
Cited by
66
References
37
Citations by year
2025: 3 · 2024: 1 · 2023: 5 · 2022: 2 · 2021: 7 · 2020: 3 · 2019: 1 · 2018: 3 · 2017: 3 · 2016: 1 · 2015: 1 · 2014: 1 · 2013: 2
FWCI
0.51
Type
journal article
Language
en
Open access
Locations
  • Journal of Vascular Surgery (publishedVersion)
  • PubMed (publishedVersion)
Topics
  • Health Sciences › Medicine › Surgery › Peripheral Artery Disease Management
  • Health Sciences › Medicine › Pulmonary and Respiratory Medicine › Vascular Procedures and Complications
  • Health Sciences › Medicine › Pulmonary and Respiratory Medicine › Renal and Vascular Pathologies
Keywords
race, peripheral arterial disease, lower limb ischemia, disease severity, black-white disparities, hypertension, atherosclerosis risk factors, arteriography
MeSH terms
Aged, Angiography, Black or African American, Diabetes Mellitus, Humans, Hypercholesterolemia, Hypertension, Ischemia, Leg, Male, Middle Aged, Retrospective Studies, Risk Factors, Smoking, Hypertriglyceridemia, Prevalence, White People

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