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Long-term opioid therapy: Assessment of consequences and risks
Open accessAbstract
Medical practice with respect to the use of opioids for the treatment of pain has been heavily influenced by societal perceptions of problems of addiction and by laws governing the use of opioids. To effectively use opioids for the treatment of chronic pain, physicians must recognize pervasive, but clinically often irrelevant societal and legal influences on prescribing, while at the same time respecting opioid properties which may lead to unwanted consequences in the course of opioid therapy. This paper reviews history and legislation that has shaped medical prescribing of opioids, examines the potential risks and consequences of long-term opioid therapy and assesses three models of long-term opioid therapy.
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“Thus, the ACT group was at higher risk of persistent pain, pain-related disability, depression, and long-term, high-dose opioid use.6,13,41”
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Metadata
- Authors
- Savage, S. R.
- Affiliations
- Dartmouth–Hitchcock Medical Center (US)
- Corresponding author
- Savage, Seddon R.
- ORCID
- Savage, Seddon R.
- Venue
- Journal of Pain and Symptom Management
- Publisher
- Elsevier BV
- Published
- 1996-05
- Volume
- 11
- Issue
- 5
- Pages
- 274-286
- ISSN
- 0885-3924 (ISSN-L)
- OpenAlex
- W2059291642
- Cited by
- 176
- References
- 64
- Citations by year
- 2024: 3 · 2023: 2 · 2022: 2 · 2021: 3 · 2020: 4 · 2019: 4 · 2018: 4 · 2017: 7 · 2016: 1 · 2015: 5 · 2014: 1 · 2013: 4 · 2012: 7
- FWCI
- 1.55
- Type
- journal article
- Language
- en
- Open access
- bronze
- doi.org
- Licence
- Locations
- Journal of Pain and Symptom Management (publishedVersion)
- PubMed (publishedVersion)
- Topics
- Health Sciences › Medicine › Public Health, Environmental and Occupational Health › Opioid Use Disorder Treatment
- Health Sciences › Medicine › Anesthesiology and Pain Medicine › Pain Management and Opioid Use
- Health Sciences › Medicine › Anesthesiology and Pain Medicine › Anesthesia and Pain Management
- Keywords
- long-term opioid therapy, chronic pain, opioid prescribing, opioid use disorder, opioid risks
- MeSH terms
- Analgesics, Opioid, Drug Administration Schedule, Drug Tolerance, Humans, Opioid-Related Disorders, Risk Assessment
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