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Long-term opioid therapy: Assessment of consequences and risks
Open accessAbstract
Medical practice with respect to the use of opioids for the treatment of pain has been heavily influenced by societal perceptions of problems of addiction and by laws governing the use of opioids. To effectively use opioids for the treatment of chronic pain, physicians must recognize pervasive, but clinically often irrelevant societal and legal influences on prescribing, while at the same time respecting opioid properties which may lead to unwanted consequences in the course of opioid therapy. This paper reviews history and legislation that has shaped medical prescribing of opioids, examines the potential risks and consequences of long-term opioid therapy and assesses three models of long-term opioid therapy.
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“Thus, the ACT group was at higher risk of persistent pain, pain-related disability, depression, and long-term, high-dose opioid use.6,13,41”
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Metadata
- Authors
- Savage, S. R.
- Affiliations
- Dartmouth–Hitchcock Medical Center (US)
- Corresponding author
- Savage, Seddon R.
- ORCID
- Savage, Seddon R.
- Venue
- Journal of Pain and Symptom Management
- Publisher
- Elsevier BV
- Published
- 1996-05
- Volume
- 11
- Issue
- 5
- Pages
- 274-286
- ISSN
- 0885-3924 (ISSN-L)
- OpenAlex
- W2059291642
- Cited by
- 176
- References
- 64
- Citations by year
- 2024: 3 · 2023: 2 · 2022: 2 · 2021: 3 · 2020: 4 · 2019: 4 · 2018: 4 · 2017: 7 · 2016: 1 · 2015: 5 · 2014: 1 · 2013: 4 · 2012: 7
- FWCI
- 1.55
- Type
- journal article
- Language
- en
- Open access
- bronze
- doi.org
- Licence
- Locations
- Journal of Pain and Symptom Management (publishedVersion)
- PubMed (publishedVersion)
- Topics
- Health Sciences › Medicine › Public Health, Environmental and Occupational Health › Opioid Use Disorder Treatment
- Health Sciences › Medicine › Anesthesiology and Pain Medicine › Pain Management and Opioid Use
- Health Sciences › Medicine › Anesthesiology and Pain Medicine › Anesthesia and Pain Management
- Keywords
- long-term opioid therapy, chronic pain, opioid prescribing, opioid use disorder, opioid risks
- MeSH terms
- Analgesics, Opioid, Drug Administration Schedule, Drug Tolerance, Humans, Opioid-Related Disorders, Risk Assessment
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
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