Localization of a human T-cell-specific gene, RANTES (D17S136E), to chromosome 17q11.2-q12

Donlon, T.A.; Krensky, A.M.; Wallace, M.R.; Collins, F.S.; Lovett, M.; Clayberger, C.

doi:10.1016/0888-7543(90)90485-d

Cited by 78Chemokine receptors and signalingGenomics and Chromatin DynamicsGenetic Associations and Epidemiology

Localization of a human T-cell-specific gene, RANTES (D17S136E), to chromosome 17q11.2-q12

Donlon, T.A., Krensky, A.M., Wallace, M.R., Collins, F.S., Lovett, M., Clayberger, C.·1990·Genomics

DOI 10.1016/0888-7543(90)90485-d

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Abstract

We report here the localization of the gene for a human T-cell-specific molecule, designated RANTES, to human chromosome region 17q11.2-q12 by in situ hybridization and analysis of somatic cell hybrids using a cDNA probe to the gene. We have recently shown that this gene, which encodes a small, secreted, putative lymphokine, is a member of a larger gene family some of whose members reside on chromosome 4 but most of whose members have not to date been mapped. A secondary hybridization peak was noted on the region of human chromosome 5q31-q34, which may represent the location of other members of the gene family. Interestingly, this latter region overlaps with the location of an extended linked cluster of growth factor and receptor genes, some of which may be coregulated with members of the RANTES gene family.

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“CCL5, or the regulated upon activation normal T cell expressed and secreted (RANTES), is an inflammatory chemoattractant for T cells, basophils, eosinophils, and dendritic cells to the site of inflammation (75).”
From Macrophage Cytokines: Involvement in Immunity and Infectious Diseases (2014) · cites this paper as [75]

A technique for radiolabeling DNA restriction endonuclease fragments to high specific activity
Feinberg, A. P., & Vogelstein, B. (1983) · Analytical Biochemistry · doi:10.1016/0003-2697(83)90418-9 · Cited by 24,512 · see citing works
Structure of the receptor for platelet-derived growth factor helps define a family of closely related growth factor receptors
Yarden, Y., Escobedo, J. A., Kuang, W.-J., Yang‐Feng, T. L., Daniel, T. O., Tremble, P., Chen, E. Y., Ando, M. E., Harkins, R. N., Francke, U., et al. (1986) · Nature · doi:10.1038/323226a0 · Cited by 1,208 · see citing works
Molecular cloning of a human monocyte-derived neutrophil chemotactic factor (MDNCF) and the induction of MDNCF mRNA by interleukin 1 and tumor necrosis factor.
Matsushima, K., Morishita, K., Yoshimura, T., Lavu, S., Kobayashi, Y., Lew, W., Appella, E., Kung, H. F., Leonard, E. J., & Oppenheim, J. J. (1988) · The Journal of Experimental Medicine · doi:10.1084/jem.167.6.1883 · Cited by 1,021 · see citing works
γ-Interferon transcriptionally regulates an early-response gene containing homology to platelet proteins
Luster, A. D., Unkeless, J. C., & Ravetch, J. V. (1985) · Nature · doi:10.1038/315672a0 · Cited by 944 · see citing works
Localization of single copy DNA sequences on G-banded human chromosomes by in situ hybridization
Harper, M., & Saunders, G. F. (1981) · Chromosoma · doi:10.1007/bf00327364 · Cited by 819 · see citing works
Gene for von Recklinghausen Neurofibromatosis Is in the Pericentromeric Region of Chromosome 17
Barker, D. F., Wright, E., Nguyen, K., Cannon, L. A., Fain, P. R., Goldgar, D., Bishop, D. T., Carey, J. C., Baty, B. J., Kivlin, J., et al. (1987) · Science · doi:10.1126/science.3107130 · Cited by 695 · see citing works
cDNA for the human beta 2-adrenergic receptor: a protein with multiple membrane-spanning domains and encoded by a gene whose chromosomal location is shared with that of the receptor for platelet-derived growth factor.
Kobilka, B. K., Dixon, R. A. F., Frielle, T., Dohlman, H. G., Bolanowski, M. A., Sigal, I. S., Yang-Feng, T. L., Francke, U., Caron, M. G., & Lefkowitz, R. J. (1987) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.84.1.46 · Cited by 679 · see citing works
Human endothelial cell growth factor: cloning, nucleotide sequence, and chromosome localization.
Jaye, M., Howk, R., Burgess, W. H., Ricca, G., Chiu, I.-M., Ravera, M., O'Brien, S. J., Modi, W., Maciag, T., & Drohan, W. N. (1986) · Science · doi:10.1126/science.3523756 · Cited by 616 · see citing works
Macrophages secrete a novel heparin-binding protein with inflammatory and neutrophil chemokinetic properties.
Wolpe, S. D., Davatelis, G., Sherry, B. A., Beutler, B., HESSE, D. G., Nguyen, H. T., Moldawer, L. L., Nathan, C. F., Lowry, S. F., & Cerami, A. (1988) · The Journal of Experimental Medicine · doi:10.1084/jem.167.2.570 · Cited by 571 · see citing works
Purification and amino acid sequencing of NAF, a novel neutrophil-activating factor produced by monocytes
Walz, A., Peveri, P., Aschauer, H., & Baggiolini, M. (1987) · Biochemical and Biophysical Research Communications · doi:10.1016/0006-291x(87)90432-3 · Cited by 506 · see citing works
A human T cell-specific molecule is a member of a new gene family.
Schall, T. J., Jongstra, J., Dyer, B., Jorgensen, J. L., Clayberger, C., Davis, M. M., & Krensky, A. M. (1988) · The Journal of Immunology · doi:10.4049/jimmunol.141.3.1018 · Cited by 496 · see citing works
Self-citation
Cloning and expression of JE, a gene inducible by platelet-derived growth factor and whose product has cytokine-like properties.
Rollins, B. J., Morrison, E. D., & Stiles, C. D. (1988) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.85.11.3738 · Cited by 438 · see citing works
The CD14 Monocyte Differentiation Antigen Maps to a Region Encoding Growth Factors and Receptors
Goyert, S. M., Ferrero, E., Rettig, W. J., Yenamandra, A., Obata, F., & Beau, M. M. L. (1988) · Science · doi:10.1126/science.2448876 · Cited by 352 · see citing works
Molecular characterization and chromosomal mapping of melanoma growth stimulatory activity, a growth factor structurally related to beta‐thromboglobulin.
Richmond, A., Balentien, E., Thomas, H. G., Flaggs, G., Barton, D. E., Spiess, J., Bordoni, R., Francke, U., & Derynck, R. (1988) · The EMBO Journal · doi:10.1002/j.1460-2075.1988.tb03042.x · Cited by 351 · see citing works
A novel, NH2-terminal sequence-characterized human monokine possessing neutrophil chemotactic, skin-reactive, and granulocytosis-promoting activity.
Damme, J. V., BEEUMEN, J. V., Opdenakker, G., & Billiau, A. (1988) · The Journal of Experimental Medicine · doi:10.1084/jem.167.4.1364 · Cited by 314 · see citing works
The Human Gene Encoding GM-CSF Is at 5q21-q32, the Chromosome Region Deleted in the 5q - Anomaly
Huebner, K., Isobe, M., Croce, C. M., Golde, D. W., Kaufman, S., & Gasson, J. C. (1985) · Science · doi:10.1126/science.2999978 · Cited by 237 · see citing works
Induction of mRNA for a serine protease and a beta-thromboglobulin-like protein in mitogen-stimulated human leukocytes.
Schmid, J., & Weissmann, C. (1987) · The Journal of Immunology · doi:10.4049/jimmunol.139.1.250 · Cited by 231 · see citing works
Precise localization of NF1 to 17q11.2 by balanced translocation.
Ledbetter, D. H., Rich, D. C., O'Connell, P., Leppert, M., & Carey, J. C. (1989) · PubMed · Cited by 214 · see citing works
A family of small inducible proteins secreted by leukocytes are members of a new superfamily that includes leukocyte and fibroblast-derived inflammatory agents, growth factors, and indicators of various activation processes.
Brown, K. D., Zurawski, S., Mosmann, T. R., & Zurawski, G. (1989) · The Journal of Immunology · doi:10.4049/jimmunol.142.2.679 · Cited by 204 · see citing works
Transformation by Rous sarcoma virus induces a novel gene with homology to a mitogenic platelet protein
Sugano, S., Stoeckle, M. Y., & Hanafusa, H. (1987) · Cell · doi:10.1016/0092-8674(87)90284-4 · Cited by 193 · see citing works
Expression of the human c-fms proto-oncogene in hematopoietic cells and its deletion in the 5q− syndrome
Nienhuis, A. W., Bunn, H. F., Turner, P. H., Gopal, T. V., Nash, W. G., O’Brien, S. J., & Sherr, C. J. (1985) · Cell · doi:10.1016/0092-8674(85)90099-6 · Cited by 174 · see citing works
Tandem linkage of human CSF-1 receptor (c-fms) and PDGF receptor genes
Roberts, W., Look, A. T., Roussel, M. F., & Sherr, C. J. (1988) · Cell · doi:10.1016/0092-8674(88)90224-3 · Cited by 165 · see citing works
The interleukin 3 gene is located on human chromosome 5 and is deleted in myeloid leukemias with a deletion of 5q.
Beau, M. M. L., Epstein, N. D., O’Brien, S. J., Nienhuis, A. W., Yang, Y., Clark, S., & Rowley, J. D. (1987) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.84.16.5913 · Cited by 164 · see citing works
Chromosomal localisation of the human homologues to the oncogenes erbA and B.
Spurr, N. K., Solomon, E., Jansson, M., Sheer, D., Goodfellow, P. N., Bodmer, W. F., & Vennström, B. (1984) · The EMBO Journal · doi:10.1002/j.1460-2075.1984.tb01777.x · Cited by 164 · see citing works
Assignment of CSF-1 to 5q33.1: evidence for clustering of genes regulating hematopoiesis and for their involvement in the deletion of the long arm of chromosome 5 in myeloid disorders.
Pettenati, M. J., Beau, M. M. L., Lemons, R. S., Shima, E. A., Kawasaki, E. S., Larson, R. A., Sherr, C. J., Dı́az, M. O., & Rowley, J. D. (1987) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.84.9.2970 · Cited by 151 · see citing works
Mitogenic activation of human T cells induces two closely related genes which share structural similarities with a new family of secreted factors.
Zipfel, P. F., Balke, J., Irving, S. G., Kelly, K., & Siebenlist, U. K. (1989) · The Journal of Immunology · doi:10.4049/jimmunol.142.5.1582 · Cited by 146 · see citing works
The human genes for GM-CSF and IL 3 are closely linked in tandem on chromosome 5
Yang, Y., Kovacic, S., Kriz, R., Wolf, S., Clark, S., Wellems, T., Nienhuis, A. W., & Epstein, N. (1988) · Blood · doi:10.1182/blood.v71.4.958.bloodjournal714958 · Cited by 144 · see citing works
Cloning and characterization of platelet factor 4 cDNA derived from a human erythroleukemic cell line
Poncz, M., Surrey, S., LaRocco, P., Weiss, M. J., Rappaport, E. F., Conway, T., & Schwartz, E. (1987) · Blood · doi:10.1182/blood.v69.1.219.219 · Cited by 123 · see citing works
Characterization of human platelet basic protein, a precursor form of low-affinity platelet factor 4 and .beta.-thromboglobulin
Holt, J. C., Harris, M. E., Holt, A. M., Lange, E., Henschen, A., & Niewiarowski, S. (1986) · Biochemistry · doi:10.1021/bi00356a023 · Cited by 119 · see citing works
Regional mapping panel for human chromosome 17: Application to neurofibromatosis type 1
van Tuinen, P., Rich, D. C., SUMMERS, K. M., & Ledbetter, D. H. (1987) · Genomics · doi:10.1016/0888-7543(87)90042-5 · Cited by 119 · see citing works
A human c-erbA oncogene homologue is closely proximal to the chromosome 17 breakpoint in acute promyelocytic leukemia.
Dayton, A. I., Selden, J. R., Laws, G., Dorney, D. J., Finan, J. B., Tripputi, P., Emanuel, B. S., Rovera, G., Nowell̀, P. C., & Croce, C. M. (1984) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.81.14.4495 · Cited by 119 · see citing works
The isolation and sequence of a novel gene from a human functional T cell line.
Jongstra, J., Schall, T. J., Dyer, B., Clayberger, C., Jorgensen, J. L., Davis, M. M., & Krensky, A. M. (1987) · The Journal of Experimental Medicine · doi:10.1084/jem.165.3.601 · Cited by 118 · see citing works
Self-citation
A cDNA Clone Used to Study mRNA Inducible in Human Tonsillar Lymphocytes by a Tumor Promoter1
Obaru, K., FUKUDA, M., Maeda, S., & 島田, 和. (1986) · The Journal of Biochemistry · doi:10.1093/oxfordjournals.jbchem.a135549 · Cited by 116 · see citing works
Interferon-inducible gene maps to a chromosomal band associated with a (4;11) translocation in acute leukemia cells.
Luster, A. D., Jhanwar, S. C., Chaganti, R. S. K., Kersey, J. H., & Ravetch, J. V. (1987) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.84.9.2868 · Cited by 104 · see citing works
Interleukin-5 is at 5q31 and is deleted in the 5q- syndrome
Sutherland, G., Baker, E. G., Callen, D., Campbell, H. D., Young, I., Sanderson, C. J., Garson, O. M., Lopez, A. F., & Vadas, M. (1988) · Blood · doi:10.1182/blood.v71.4.1150.1150 · Cited by 95 · see citing works
Cases of neurofibromatosis with rearrangements of chromosome 17 involving band 17q11.2
Schmidt, M. A., Michels, V. V., Dewald, G. W., Opitz, J. M., & Reynolds, J. F. (1987) · American Journal of Medical Genetics · doi:10.1002/ajmg.1320280333 · Cited by 87 · see citing works
Cloning and characterization of a novel T cell activation gene.
Burd, P. R., Freeman, G. J., Wilson, S. D., Berman, M. L., DeKruyff, R. H., Billings, P. R., & Dorf, M. E. (1987) · The Journal of Immunology · doi:10.4049/jimmunol.139.9.3126 · Cited by 85 · see citing works
Identification, cloning, and characterization of an immune activation gene.
Lipes, M. A., Napolitano, M., Jeang, K. T., CHANG, N. T., & Leonard, W. J. (1988) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.85.24.9704 · Cited by 84 · see citing works
Interleukin 4 is at 5q31 and interleukin 6 is at 7p15
Sutherland, G., Baker, E., Callen, D. F., Hyland, V. J., Wong, G. G., Clark, S., Jones, S., Eglinton, L., Shannon, M. F., Lopez, A. F., et al. (1988) · Human Genetics · doi:10.1007/bf00282171 · Cited by 83 · see citing works
The genes for basic and acidic fibroblast growth factors are on different human chromosomes
Mergia, A., Eddy, R. L., Abraham, J. A., Fiddes, J. C., & Shows, T. B. (1986) · Biochemical and Biophysical Research Communications · doi:10.1016/s0006-291x(86)80545-9 · Cited by 77 · see citing works
Physical mapping of the von Recklinghausen neurofibromatosis region on chromosome 17.
Fountain, J. W., Wallace, M. R., Am, B., O'Connell, P., White, R. L., Rich, D. C., Ledbetter, D. H., Leach, R. J., Re, F., & Menon, A. G. (1989) · PubMed · Cited by 68 · see citing works
Self-citation
Characterization of a translocation within the von Recklinghausen neurofibromatosis region of chromosome 17
MENON, A. (1989) · Genomics · doi:10.1016/0888-7543(89)90053-0 · Cited by 66 · see citing works
Physical mapping of human chromosome 17 using fragment-containing microcell hybrids
Leach, R. J. (1989) · Genomics · doi:10.1016/0888-7543(89)90043-8 · Cited by 65 · see citing works
Localization of the restriction fragment length polymorphism D14S1 (pAW-101) to chromosome 14q32.1 leads to 32.2 by in situ hybridization.
Donlon, T. A., Litt, M. J., Newcom, S. R., & Magenis, R. E. (1983) · PubMed · Cited by 38 · see citing works
Self-citation
Human platelet factor 4 gene is mapped to 4q12→q21
Griffin, C. A., Emanuel, B. S., LaRocco, P., Schwartz, E. R., & Poncz, M. (2008) · Cytogenetics and Cell Genetics · doi:10.1159/000132431 · Cited by 35 · see citing works
Chromosomal localization of the human G-CSF gene to 17q11 proximal to the breakpoint of the t(15;17) in acute promyelocytic leukemia.
Beau, M. M. L., Lemons, R. S., Carrino, J. J., Pettenati, M. J., Souza, L. M., Dı́az, M. O., & Rowley, J. D. (1987) · PubMed · Cited by 32 · see citing works
Towards an understanding of the molecular mechanisms regulating gene expression during diploidization in phylogenetically polyploid lower vertebrates
Leipoldt, M. (1983) · Human Genetics · doi:10.1007/bf00285022 · Cited by 22 · see citing works

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Sorted by citations

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Arango Duque, G., & Descoteaux, A. (2014) · Frontiers in Immunology · doi:10.3389/fimmu.2014.00491 · Cited by 2,708 · see citing works
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Background
Interleukin-8 and related chemotactic cytokines--CXC and CC chemokines.
Baggiolini, M., Dewald, B., & Moser, B. (1994) · PubMed · Cited by 2,232 · see citing works
lnterleukin-8 and Related Chemotactic Cytokines—CXC and CC Chemokines
Baggiolini, M., Dewald, B., & Moser, B. (1993) · Advances in immunology · doi:10.1016/s0065-2776(08)60509-x · Cited by 1,672 · see citing works
Biology of the rantes/sis cytokine family
Schall, T. J. (1991) · Cytokine · doi:10.1016/1043-4666(91)90013-4 · Cited by 675 · see citing works
Suppression of tumor formation in vivo by expression of the JE gene in malignant cells.
Rollins, B. J., & Sunday, M. E. (1991) · Molecular and Cellular Biology · doi:10.1128/mcb.11.6.3125 · Cited by 217 · see citing works
Alkannins and Shikonins: A New Class of Wound Healing Agents
Papageorgiou, V. P., Assimopoulou, A. N., & Ballis, A. (2008) · Current Medicinal Chemistry · doi:10.2174/092986708786848532 · Cited by 204 · see citing works
Breast cancer cells condition lymphatic endothelial cells within pre-metastatic niches to promote metastasis
Lee, E., Fertig, E. J., Jin, K., Sukumar, S., Pandey, N. B., & Popel, A. S. (2014) · Nature Communications · doi:10.1038/ncomms5715 · Cited by 197 · see citing works
Hantavirus Infection Induces the Expression of RANTES and IP-10 without Causing Increased Permeability in Human Lung Microvascular Endothelial Cells
Sundstrom, J. B., McMullan, L. K., Spiropoulou, C. F., Hooper, W. C., Ansari, A. A., Peters, C. J., & Rollin, P. E. (2001) · Journal of Virology · doi:10.1128/jvi.75.13.6070-6085.2001 · Cited by 142 · see citing works
CCL5 as a potential immunotherapeutic target in triple-negative breast cancer
Lv, D., Zhang, Y., Kim, H.-J., Zhang, L., & Ma, X. (2013) · Cellular and Molecular Immunology · doi:10.1038/cmi.2012.69 · Cited by 95 · see citing works
Recent Advances in Discovering the Role of CCL5 in Metastatic Breast Cancer
Khalid, A., Wolfram, J., Ferrari, I., Mu, C., Mai, J., Yang, Z., Zhao, Y., Mauro Ferrari, B., Ma, X., & Shen, H. (2015) · Mini-Reviews in Medicinal Chemistry · doi:10.2174/138955751513150923094709 · Cited by 77 · see citing works
Role of Eosinophils in Intestinal Inflammation and Fibrosis in Inflammatory Bowel Disease: An Overlooked Villain?
Jacobs, I., Ceulemans, M., Wauters, L. I., Breynaert, C. M., Vermeire, S., Verstockt, B., & Vanuytsel, T. (2021) · Frontiers in Immunology · doi:10.3389/fimmu.2021.754413 · Cited by 72 · see citing works
Effects of CCL5 on the biological behavior of breast cancer and the mechanisms of its interaction with tumor‑associated macrophages
An, G., Wu, F., Huang, S., Lu, F., Bai, J., Gu, S., & Zhao, X. (2019) · Oncology Reports · doi:10.3892/or.2019.7344 · Cited by 71 · see citing works
The RANTES promoter polymorphism: A genetic risk factor for near-fatal asthma in Chinese children
Yao, T., Kuo, M., See, L., Chen, L., Yan, D., Ou, L.-S., Shaw, C.-K., & Huang, J. (2003) · Journal of Allergy and Clinical Immunology · doi:10.1067/mai.2003.1506 · Cited by 69 · see citing works
Eosinophil recruitment is associated with IL-5, but not with RANTES, twenty–four hours after allergen challenge
Sur, S. A., Kita, H., Gleich, G. J., Chenier, T. C., & Hunt, L. W. (1996) · Journal of Allergy and Clinical Immunology · doi:10.1016/s0091-6749(96)70195-1 · Cited by 65 · see citing works
Human gene polymorphisms and their possible impact on the clinical outcome of SARS-CoV-2 infection
Hashemi, S. M. A., Thijssen, M., Hosseini, S. Y., Tabarraei, A., Pourkarim, M. R., & Sarvari, J. (2021) · Archives of Virology · doi:10.1007/s00705-021-05070-6 · Cited by 53 · see citing works
MicroRNAs expressed by human cytomegalovirus
Zhang, L., Yu, J., & Liu, Z. (2020) · Virology Journal · doi:10.1186/s12985-020-1296-4 · Cited by 46 · see citing works
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Gade‐Andavolu, R., Comings, D. E., MacMurray, J. P., Vuthoori, R., Tourtellotte, W. W., Nagra, R. M., & Cone, L. A. (2004) · Multiple Sclerosis Journal · doi:10.1191/1352458504ms1080oa · Cited by 42 · see citing works
Association of IL-13, RANTES, and leukotriene C4 synthase gene promoter polymorphisms with asthma and/or atopy in African Americans
Moissidis, I. J., Chinoy, B., Yanamandra, K., Napper, D., Thurmon, T. F., Bocchini, J. A., & Bahna, S. L. (2005) · Genetics in Medicine · doi:10.1097/01.gim.0000170994.24960.48 · Cited by 41 · see citing works
Suppression of Tumor Formation In Vivo by Expression of the JE Gene in Malignant Cells
Rollins, B. J., & Sunday, M. E. (1991) · Molecular and Cellular Biology · doi:10.1128/mcb.11.6.3125-3131.1991 · Cited by 41 · see citing works
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Functional roles of CCL5/RANTES in liver disease
Chen, L., Zhang, Q., Yu, C. J., Wang, F., & Kong, X. (2020) · Liver Research · doi:10.1016/j.livres.2020.01.002 · Cited by 37 · see citing works
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Murakami, K., Nomiyama, H., Miura, R., Follens, A., Fiten, P., Coillie, E. V., Damme, J. V., & Opdenakker, G. (1997) · DNA and Cell Biology · doi:10.1089/dna.1997.16.173 · Cited by 37 · see citing works
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Ni, J., Liu, S., Qi, F., Xiao, L., Yu, S., Feng, J., & Zheng, Y. (2020) · Annals of Translational Medicine · doi:10.21037/atm.2020.01.73 · Cited by 35 · see citing works
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Rollins, B. J., Morton, C. C., Ledbetter, D. H., Eddy, R. L., & Shows, T. B. (1991) · Genomics · doi:10.1016/0888-7543(91)90338-f · Cited by 34 · see citing works
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Kumar, D., Sharma, A., & Sharma, L. K. (2020) · Current Neuropharmacology · doi:10.2174/1570159x18666200203101828 · Cited by 33 · see citing works
Short communication: Supplementation of colostrum and milk with 5-hydroxy-l-tryptophan affects immune factors but not growth performance in newborn calves
Hernández-Castellano, L. E., Özçelik, R., Hernandez, L. L., & Bruckmaier, R. M. (2017) · Journal of Dairy Science · doi:10.3168/jds.2017-13501 · Cited by 32 · see citing works
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ZHANG, L., Redington, A. E., & Holgate, S. T. (1994) · Clinical & Experimental Allergy · doi:10.1111/j.1365-2222.1994.tb02720.x · Cited by 32 · see citing works
Nucleotide sequence of the third cytokine LD78 gene and mapping of all three LD78 gene loci to human chromosome 17
Hirashima, M., Ono, T., Nakao, M., Nishi, H., Kimura, A., Nomiyama, H., HAMADA, F., Yoshida, M., & 島田, 和. (1992) · DNA sequence · doi:10.3109/10425179209034019 · Cited by 30 · see citing works
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Zhou, Z., Zeiter, S., Schmid, T., Sakai, D., Iatridis, J. C., Zhou, G., Richards, R. G., Alini, M., Grad, S., & Li, Z. (2018) · Cartilage · doi:10.1177/1947603518764263 · Cited by 29 · see citing works
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Napolitano, M., Modi, W. S., Cevario, S. J., Gnarra, J. R., Seuánez, H. N., & Leonard, W. J. (1991) · Journal of Biological Chemistry · doi:10.1016/s0021-9258(19)47404-8 · Cited by 26 · see citing works
Association between RANTES polymorphisms and asthma severity among Tunisian children
Lachheb, J., Chelbi, H., Hamzaoui, K., & Hamzaoui, A. (2007) · Human Immunology · doi:10.1016/j.humimm.2007.04.004 · Cited by 25 · see citing works
Zearalenone inhibits T cell chemotaxis by inhibiting cell adhesion and migration related proteins
Cai, G., Pan, S., Feng, N., Zou, H., Gu, J., Yuan, Y., Liu, X., Liu, Z., & Bian, J. (2019) · Ecotoxicology and Environmental Safety · doi:10.1016/j.ecoenv.2019.03.045 · Cited by 22 · see citing works
Epigenetic Modification of the CCL5/CCR1/ERK Axis Enhances Glioma Targeting in Dedifferentiation-Reprogrammed BMSCs
Chen, R., Lee, W., Zhang, X., Zhang, J. T., Lin, S., Xu, L., Huang, B., Yang, F. Y., Liu, H. L., Wang, B., et al. (2017) · Stem Cell Reports · doi:10.1016/j.stemcr.2017.01.016 · Cited by 20 · see citing works
Investigation of candidate molecular biomarkers for expression profile analysis of the Gene expression omnibus (GEO) in acute lymphocytic leukemia (ALL)
Zhang, G., Wang, H.-T., Zhu, K., Yang, Y., Li, J., Jiang, H., & Liu, Z. (2019) · Biomedicine & Pharmacotherapy · doi:10.1016/j.biopha.2019.109530 · Cited by 20 · see citing works
Human cytomegalovirus encoded microRNAs: hitting targets
Ng, K. R., Li, J. Y. Z., & Gleadle, J. (2015) · Expert Review of Anti-infective Therapy · doi:10.1586/14787210.2015.1106939 · Cited by 16 · see citing works
RANTES gene mRNA expression and its −403 G/A promoter polymorphism in coronary artery disease
Tavakkoly‐Bazzaz, J., Amiri, P., Tajmir-Riahi, M., Javidi, D., Khojasteh-Fard, M., Taheri, Z., Tabrizi, A. S., Keramatipour, M., & Amoli, M. M. (2011) · Gene · doi:10.1016/j.gene.2011.07.019 · Cited by 16 · see citing works
Bioinformatic Identification of Neuroblastoma Microenvironment-Associated Biomarkers with Prognostic Value
Wang, Y., Luo, H., Cao, J., & Ma, C. (2020) · Journal of Oncology · doi:10.1155/2020/5943014 · Cited by 14 · see citing works
The effect of CCL5 on the immune cells infiltration and the prognosis of patients with kidney renal clear cell carcinoma
Bai, S., Wu, Y., Yan, Y., Kang, H., Zhang, J., Ma, W., Gao, Y., Hui, B., Li, R., Zhang, X., et al. (2020) · International Journal of Medical Sciences · doi:10.7150/ijms.51126 · Cited by 14 · see citing works
RANTES Gene Promoter Polymorphisms Are Associated with Bronchial Hyperresponsiveness in Korean Children with Asthma
Sohn, M. H., Kim, S., Kim, K. W., Jee, H. M., Park, H., & Kim, K.-E. (2007) · Lung · doi:10.1007/s00408-007-9049-3 · Cited by 13 · see citing works
Resequencing of the CCL5 and CCR5 genes and investigation of variants for association with diabetic nephropathy
Pettigrew, K. A., McKnight, A. J., Patterson, C., Kilner, J., Sadlier, D. M., & Maxwell, A. P. (2010) · Journal of Human Genetics · doi:10.1038/jhg.2010.15 · Cited by 13 · see citing works
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Gong, Z., Tang, J., Xiang, T., Zhang, L., Liao, Q., Liu, W. Y., & Wang, Y. (2013) · PLoS ONE · doi:10.1371/journal.pone.0060683 · Cited by 12 · see citing works
Association between regulated upon activation, normal T cells expressed and secreted (RANTES) -28C/G polymorphism and asthma risk - A Meta-Analysis
Fang, Q., Wang, F., & Zhao, D. (2010) · International Journal of Medical Sciences · doi:10.7150/ijms.7.55 · Cited by 11 · see citing works
CCL5 is induced by TLR 3 signaling in HuCCT1 human biliary epithelial cells: possible involvement in the pathogenesis of biliary atresia
Shimada, T., Imaizumi, T., Shirai, K., Tatsuta, T., Kimura, T., Hayakari, R., Yoshida, H., Matsumiya, T., Kijima, H., Mizukami, H., et al. (2017) · Biomedical Research · doi:10.2220/biomedres.38.269 · Cited by 11 · see citing works
Gene expression of RANTES
Nelson, P. J., Pattison, J. M., & Krensky, A. M. (1997) · Methods in enzymology on CD-ROM/Methods in enzymology · doi:10.1016/s0076-6879(97)87012-7 · Cited by 11 · see citing works
Self-citation
Alzheimer's disease and HIV associated dementia related genes: I. location and function
Shapshak, P., Rodriguez, H. E., Kayathri, R., Levine, A. J., Chiappelli, F., & Minagar, A. (2008) · Bioinformation · doi:10.6026/97320630002348 · Cited by 10 · see citing works
A high-resolution map of the chromosomal region surrounding the nude gene
Blackburn, C. C., Griffith, J., & Morahan, G. (1995) · Genomics · doi:10.1016/0888-7543(95)80215-8 · Cited by 10 · see citing works
Heparan sulfate-dependent phase separation of CCL5 and its chemotactic activity
Yu, X., Duan, G., Pei, P., Chen, L., Gu, R., Hu, W., Zhang, H., Wang, Y., Gong, L., Liu, L., et al. (2024) · eLife · doi:10.7554/elife.93871.4 · Cited by 9 · see citing works
LSHGD: A database for human leprosy susceptible genes
Doss, C. G. P., Nagasundaram, N., Srajan, J., & Chakraborty, C. (2012) · Genomics · doi:10.1016/j.ygeno.2012.06.010 · Cited by 9 · see citing works
Association between serotonin transporter gene polymorphisms and childhood asthma
Farjadian, S., Moghtaderi, M., Fakhraei, B., Nasiri, M., & Farjam, M. (2013) · Journal of Asthma · doi:10.3109/02770903.2013.834503 · Cited by 8 · see citing works
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Zhao, J., She, S., Xie, L., Chen, X., Mo, C., Huang, L., Tang, W., & Chen, X. (2015) · AIDS Research and Human Retroviruses · doi:10.1089/aid.2015.0312 · Cited by 8 · see citing works
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(2021) · Biointerface Research in Applied Chemistry · doi:10.33263/briac123.28132825 · Cited by 6 · see citing works
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de Miranda, C. T. C. B. C., Fagundes, D. J., de Miranda, E., Simões, R. S., Carbonel, A. A. F., Florencio‐Silva, R., & Taha, M. O. (2019) · Acta Cirúrgica Brasileira · doi:10.1590/s0102-865020190050000001 · Cited by 6 · see citing works
Heparan sulfate-dependent phase separation of CCL5 and its chemotactic activity
Yu, X., Duan, G., Pei, P., Chen, L., Gu, R., Hu, W., Zhang, H., Wang, Y., Gong, L., Liu, L., et al. (2024) · eLife · doi:10.7554/elife.93871 · Cited by 4 · see citing works
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Rakoczy, K., Kaczor, J., Sołtyk, A., Jonderko, L., Sędzik, M., Lizon, J., Lewandowska, A., Saczko, M., & Kulbacka, J. (2024) · Molecular and Cellular Endocrinology · doi:10.1016/j.mce.2024.112264 · Cited by 4 · see citing works
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McCarty, E., Yu, J. D., Ninh, V. K., Calcagno, D. M., Lee, J., & King, K. R. (2023) · Frontiers in Immunology · doi:10.3389/fimmu.2023.1199730 · Cited by 4 · see citing works
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Li, J., Diao, H., Zhao, D., & Zhang, J. (2010) · Archives of Medical Science · doi:10.5114/aoms.2010.19287 · Cited by 4 · see citing works
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de Miranda, C. T. C. B. C., Fagundes, D. J., de Miranda, E., Simões, R. S., & Taha, M. O. (2018) · Acta Cirúrgica Brasileira · doi:10.1590/s0102-865020180120000007 · Cited by 4 · see citing works
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Wolszczak-Biedrzycka, B., Cieślikiewicz, B., Studniarz, F., Dąbrowski, Ł., Fąs, M., Matyszkiewicz–Suchodolska, K., Harasimowicz, M., & Dorf, J. (2025) · Frontiers in Immunology · doi:10.3389/fimmu.2025.1662643 · Cited by 3 · see citing works
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Nelson, P. J., Pattison, J. M., & Krensky, A. M. (1998) · Elsevier eBooks · doi:10.1016/b978-012498340-3/50030-0 · Cited by 3 · see citing works
Self-citation
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Lenz, M. W., Schönbauer, R., Stojković, S., Lee, J., Gatterer, C., Lichtenauer, M., Paar, V., Emich, M., Fritzer‐Szekeres, M., Strametz‐Juranek, J., et al. (2022) · International Journal of Environmental Research and Public Health · doi:10.3390/ijerph19148658 · Cited by 3 · see citing works
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Fırat, A. A. (2022) · Biochemistry · doi:10.5772/intechopen.107183 · Cited by 3 · see citing works
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Ni, T., Wang, N., Mao, Z., & Yao, M. (2013) · Genetics and Molecular Research · doi:10.4238/2013.november.7.9 · Cited by 3 · see citing works
The biological, biochemical, and molecular profile of leukocyte chemotactic and activating cytokine, interleukin-8
Harada, A., Mukaida, N., & Matsushima, K. (1997) · Growth factors and cytokines in health and disease · doi:10.1016/s1874-5687(97)80028-6 · Cited by 2 · see citing works
A novel disease gene prediction method based on PPI network
Zhao, J., He, T., Hu, X. T., Wang, Y., Shen, X., Fang, M., & Yuan, J. (2014) · IEEE International Conference on Bioinformatics and Biomedicine (BIBM) · doi:10.1109/bibm.2014.6999175 · Cited by 2 · see citing works
Analysis of CCL5 Concentration in Tears of Dry Eye Patients
Choi, W. S., Lee, S.-H., & Yoon, K. C. (2011) · Journal of the Korean Ophthalmological Society · doi:10.3341/jkos.2011.52.6.658 · Cited by 2 · see citing works
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Hafid, E. S., & Ismael, M. K. (2021) · Iraqi Journal of Science · doi:10.24996/ijs.2021.62.9.5 · Cited by 2 · see citing works
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Wen, D., Du, X., Dong, J.-Z., & Cs, M. (2013) · European Journal of Inflammation · doi:10.1177/1721727x1301100207 · Cited by 1 · see citing works
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Shokri, F., Mozdarani, H., & Omrani, M. D. (2022) · PubMed Central · doi:10.22088/ijmcm.bums.11.3.244 · Cited by 1 · see citing works
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Furlan, R., Maiorino, C., Gatta, A. T., Ruffini, F., & Martino, G. (2010) · Springer eBooks · doi:10.1007/978-3-0346-0165-8_5 · Cited by 1 · see citing works
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Hajiannasab, R. (2016) · International Journal of Clinical Medicine · doi:10.4236/ijcm.2016.79066 · Cited by 1 · see citing works
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Cruz, G. D. S. (2014) · Americanae (AECID Library)
Association analysis of anti-inflammatory cytokine genes with the development of atopic allergic rhinitis
Alieva, V. (2010) · Medical and Health Science Journal · doi:10.15208/mhsj.2010.35
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Stobbe, K. (2019) · theses.fr (ABES) · doi:10.70675/6fd21bbaz72d5z4f4ez9758z9179924c7ff4

SHORT COMMUNICATION Localization of a Human T-Cell-Specific Gene, RANTES (D17S136E), to Chromosome 17ql1.2-q12
Donlon, T. A., Krensky, A. M., Wallace, M. R., Collins, F. S., Lovett, M., & CLAYBERGERt, C. (1990)
Self-citation
GENOMICS 6,548-553 (1990) SHORT COMMUNICATION Localization of a Human T-Cell-Specific Gene, RANTES (D17S136E), to Chromosome 17ql1.2-q12
Donlon, T. A., Krensky, A. M., Wallace, T. M. R., Collins, F. S., Lovett, M., & CLAYBERGERt, C. (1989)
Self-citation
Gene expression of RANTES
Nelson, P. J., Pattison, J. M., & Krensky, A. M. (1997) · Methods in enzymology on CD-ROM/Methods in enzymology · doi:10.1016/s0076-6879(97)87012-7 · Cited by 11 · see citing works
Self-citation
Genomic organization and transcriptional regulation of the RANTES chemokine gene.
Nelson, P. J., Kim, H. T., Manning, W. C., Goralski, T. J., & Krensky, A. M. (1993) · The Journal of Immunology · doi:10.4049/jimmunol.151.5.2601 · Cited by 266 · see citing works
Self-citation
Cloning, genomic organization, and chromosomal localization of the Scya5 gene encoding the murine chemokine RANTES.
Danoff, T. M., Lalley, P. A., Chang, Y.-W., Heeger, P. S., & Neilson, E. G. (1994) · The Journal of Immunology · doi:10.4049/jimmunol.152.3.1182 · Cited by 62 · see citing works

Authors: Donlon, T. A., Krensky, A. M., Wallace, M. R., Collins, F. S., Lovett, M., & Clayberger, C.
Affiliations: Stanford Medicine (US)
Howard Hughes Medical Institute (US)
ORCID: Donlon, T.A.
Wallace, M.R.
Collins, F.S.
Lovett, M.
Venue: Genomics
Publisher: Elsevier BV
Published: 1990-03
Volume: 6
Issue: 3
Pages: 548-553
ISSN: 0888-7543 (ISSN-L)
DOI: 10.1016/0888-7543(90)90485-d
OpenAlex: W2009023998
Cited by: 78
References: 52
Citations by year: 2025: 1 · 2024: 3 · 2023: 2 · 2022: 4 · 2021: 4 · 2020: 7 · 2019: 6 · 2018: 2 · 2017: 3 · 2016: 1 · 2015: 3 · 2014: 4 · 2013: 5 · 2012: 1
FWCI: 1.14
Type: journal article
Language: en
Open access: closed
Licence: www.elsevier.com/tdm/userlicense/1.0/ (tdm)
Locations: Genomics (publishedVersion)
PubMed (publishedVersion)
Deep Blue (University of Michigan) (submittedVersion)
Funders: American Heart Association
National Institutes of Health (5r01ns023410-05, 5r01ns024327-08)
National Institute of Diabetes and Digestive and Kidney Diseases (DK 35008)
National Institute of Neurological Disorders and Stroke (NS 23410, NS24327)
Topics: Health Sciences › Medicine › Oncology › Chemokine receptors and signaling
Life Sciences › Biochemistry, Genetics and Molecular Biology › Molecular Biology › Genomics and Chromatin Dynamics
Life Sciences › Biochemistry, Genetics and Molecular Biology › Genetics › Genetic Associations and Epidemiology
Keywords: RANTES, gene mapping, lymphokines, gene family, somatic cell hybrids, in situ hybridization
MeSH terms: Amino Acid Sequence, Chromosomes, Human, Pair 17, Gene Expression Regulation, Genes, Multigene Family, Humans, Lymphokines, Molecular Sequence Data, Nucleic Acid Hybridization, Sequence Homology, Nucleic Acid, T-Lymphocytes, Chemokine CCL5

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Localization of a human T-cell-specific gene, RANTES (D17S136E), to chromosome 17q11.2-q12

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