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The proliferation of MAP kinase signaling pathways in yeast
Open accessAbstract
Mitogen-activated protein kinases function in at least five, physiologically distinct, signaling pathways in yeast. These include pathways that mediate response to mating pheromone, pseudohyphal development and invasive growth, cell integrity, sporulation, and response to high extracellular osmolarity. These kinases and their upstream activating kinases comprise signaling modules that, in at least some cases, exist as multiprotein complexes. Studies during the past year have revealed that the Ste5 protein of the mating pheromone response pathway serves as a scaffold to promote interactions among the protein kinases in this pathway, and to prevent their interaction with kinases of other modules.
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Cited by
Whitmarsh, A. J., & Davis, R. J. (1996) · Journal of Molecular Medicine · doi:10.1007/s001090050063 · Cited by 1,543
Cell Wall Integrity Signaling in Saccharomyces cerevisiae
Levin, D. E. (2005) · Microbiology and Molecular Biology Reviews · doi:10.1128/mmbr.69.2.262-291.2005 · Cited by 1,136
Self-citationSounding the Alarm: Protein Kinase Cascades Activated by Stress and Inflammation
Kyriakis, J. M., & Avruch, J. (1996) · Journal of Biological Chemistry · doi:10.1074/jbc.271.40.24313 · Cited by 1,084
Roberts, C. J., Nelson, B., Marton, M. J., Stoughton, R., Meyer, M. R., Bennett, H. A., He, Y. D., Dai, H., Walker, W. L., Hughes, T. R., et al. (2000) · Science · doi:10.1126/science.287.5454.873 · Cited by 855
Protein kinase cascades activated by stress and inflammatory cytokines
Kyriakis, J. M., & Avruch, J. (1996) · BioEssays · doi:10.1002/bies.950180708 · Cited by 709
Metadata
- Authors
- Levin, D. E., & Errede, B.
- Venue
- Current Opinion in Cell Biology
- Publisher
- Elsevier BV
- Published
- 1995-01
- Volume
- 7
- Issue
- 2
- Pages
- 197-202
- ISSN
- 0955-0674 (ISSN-L)
- OpenAlex
- W2028070789
- Cited by
- 238
- References
- 0
- FWCI
- 3.27
- Type
- journal article
- Language
- en
- Open access
- hybrid
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