The DOI matches its Crossref record; 32 of the 32 references it cites were found in a registry or an index.
Glycosylation inhibitors in biology and medicine
Open accessAbstract
Glycosidase inhibitors are moving increasingly out of the laboratory and into the clinic as potential agents for the treatment of diseases including diabetes, AIDS and cancer. These compounds, originally isolated from natural sources and utilized for unraveling the glycosylation pathways involved in post-translational modification of glycoproteins, have multiple effects that are only now being fully appreciated. In addition to their ability to inhibit processing exoglycosidases, lysosomal glycosidases and the intestinal disaccharidases involved in carbohydrate digestion, these compounds appear to have additional activities, including immunomodulatory properties and inhibition of glycolipid synthesis, which continue to expand their range of potential uses.
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Cites
Biological roles of oligosaccharides: all of the theories are correct
Varki, A. (1993) · Glycobiology · doi:10.1093/glycob/3.2.97 · Cited by 5,195
ASSEMBLY OF ASPARAGINE-LINKED OLIGOSACCHARIDES
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β1-6 Branching of Asn-Linked Oligosaccharides Is Directly Associated with Metastasis
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Amino-sugar glycosidase inhibitors: versatile tools for glycobiologists
Winchester, B., & Fleet, G. W. J. (1992) · Glycobiology · doi:10.1093/glycob/2.3.199 · Cited by 497
N-butyldeoxynojirimycin is a novel inhibitor of glycolipid biosynthesis.
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Cited by
Polyhydroxylated alkaloids—Natural occurrence and therapeutic applications
Watson, A. A., Fleet, G. W. J., Asano, N., Molyneux, R. J., & Nash, R. J. (2001) · Phytochemistry · doi:10.1016/s0031-9422(00)00451-9 · Cited by 714
α- and β-Glucosidase inhibitors: chemical structure and biological activity
Borges de Melo, E., da Silveira Gomes, A., & Carvalho, I. (2006) · Tetrahedron · doi:10.1016/j.tet.2006.08.055 · Cited by 548
Targeting glycosylation as a therapeutic approach
Dwek, R. A., Butters, T. D., Platt, F. M., & Zitzmann, N. (2002) · Nature Reviews Drug Discovery · doi:10.1038/nrd708 · Cited by 420
Investigating Cellular Metabolism of Synthetic Azidosugars with the Staudinger Ligation
Saxon, E., Luchansky, S. J., Hang, H. C., Yu, C., Lee, S. C., & Bertozzi, C. R. (2002) · Journal of the American Chemical Society · doi:10.1021/ja027748x · Cited by 309
α‐Glucosidase inhibitors as potential broad based anti‐viral agents
Mehta, A., Zitzmann, N., Rudd, P. M., Block, T. M., & Dwek, R. A. (1998) · FEBS Letters · doi:10.1016/s0014-5793(98)00525-0 · Cited by 283
Metadata
- Authors
- Jacob, G. S.
- Venue
- Current Opinion in Structural Biology
- Publisher
- Elsevier BV
- Published
- 1995-10
- Volume
- 5
- Issue
- 5
- Pages
- 605-611
- ISSN
- 0959-440X (ISSN-L)
- OpenAlex
- W2082002380
- Cited by
- 278
- References
- 32
- FWCI
- 0.51
- Type
- journal article
- Language
- en
- Open access
- hybrid
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Data sources
Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
