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Carbon nanotubes as nanomedicines: From toxicology to pharmacology☆
Abstract
Various biomedical applications of carbon nanotubes have been proposed in the last few years leading to the emergence of a new field in diagnostics and therapeutics. Most of these applications will involve the administration or implantation of carbon nanotubes and their matrices into patients. The toxicological and pharmacological profile of such carbon nanotube systems developed as nanomedicines will have to be determined prior to any clinical studies undertaken. This review brings together all the toxicological and pharmacological in vivo studies that have been carried out using carbon nanotubes, to offer the first summary of the state-of-the-art in the pharmaceutical development of carbon nanotubes on the road to becoming viable and effective nanomedicines.
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Cites
Donaldson, K., Aitken, R., Tran, L., Stone, V., Duffin, R., Forrest, G., & Alexander, A. (2006) · Toxicological Sciences · doi:10.1093/toxsci/kfj130 · Cited by 1,167
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In Vivo Pharmacokinetics, Long-Term Biodistribution, and Toxicology of PEGylated Graphene in Mice
Yang, K., Wan, J., Zhang, S., Zhang, Y., Lee, S.-T., & Liu, Z. (2011) · ACS Nano · doi:10.1021/nn1024303 · Cited by 848
Zhang, Q., Huang, J., Qian, W., Zhang, Y., & Wei, F. (2013) · Small · doi:10.1002/smll.201203252 · Cited by 759
Multimodality Molecular Imaging of Tumor Angiogenesis
Cai, W., & Chen, X. (2008) · Journal of Nuclear Medicine · doi:10.2967/jnumed.107.045922 · Cited by 494
Nanoparticles and their interactions with the dermal barrier
Schneider, M., Stracke, F., Hansen, S., & Schaefer, U. F. (2009) · Dermato-Endocrinology · doi:10.4161/derm.1.4.9501 · Cited by 489
Metadata
- Authors
- LACERDA, L., BIANCO, A., PRATO, M., & KOSTARELOS, K.
- Venue
- Advanced Drug Delivery Reviews
- Publisher
- Elsevier BV
- Published
- 2006-12-01
- Volume
- 58
- Issue
- 14
- Pages
- 1460-1470
- ISSN
- 0169-409X (ISSN-L)
- OpenAlex
- W2162459979
- Cited by
- 839
- References
- 1
- FWCI
- 37.54
- Type
- journal article
- Language
- en
- Open access
- closed
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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
