Strategies for controlling the innate immune activity of conventional and self-amplifying mRNA therapeutics: Getting the message across

Minnaert, An-Katrien, Vanluchene, Helena, Verbeke, Rein, Lentacker, Ine, De Smedt, Stefaan C., Raemdonck, Koen, Sanders, Niek N., Remaut, Katrien·2021·Advanced Drug Delivery Reviews

Cites (253)

Items 201–252 of 252

  1. Immunogenicity and Protection Efficacy of a Naked Self-Replicating mRNA-Based Zika Virus Vaccine
    Zifu Zhong, João Paulo Portela Catani, Séan Mc Cafferty, Liesbeth Couck, Wim Van Den Broeck, Nina Gorlé, Roosmarijn E. Vandenbroucke, Bert Devriendt, Sebastian Ulbert, Lieselotte Cnops et al. · 2019 · Vaccines
  2. An element within the 5′ untranslated region of human <i>Hsp70</i> mRNA which acts as a general enhancer of mRNA translation
    Vivinus, Sandra, Baulande, Sylvain, van Zanten, Marije, Campbell, Fiona, Topley, Peter, Ellis, Jonathan H., Dessen, Philippe, Coste, Hervé · 2001 · European Journal of Biochemistry
  3. Non-viral delivery of chemically modified mRNA to the retina: Subretinal versus intravitreal administration
    Joke Devoldere, Karen Peynshaert, Heleen Dewitte, Christian Vanhove, Lies De Groef, Lieve Moons, Sinem Yilmaz Özcan, Deniz Dalkara, Stefaan C. De Smedt, Katrien Remaut · 2019 · Journal of Controlled Release
  4. Activation of the IκBα kinase (IKK) complex by double-stranded RNA-binding defective and catalytic inactive mutants of the interferon-inducible protein kinase PKR
    Tetsu M. Ishii, Hakju Kwon, John B. Hiscott, George Mosialos, Antonis E. Koromilas · 2001 · Oncogene
  5. Induction of the cellular miR-29c by influenza virus inhibits the innate immune response through protection of A20 mRNA
    Xiaoyang Zhang, Chunyan Dong, Xiaoning Sun, Zhongyi Li, Maolin Zhang, Zhenhong Guan, Ming Duan · 2014 · Biochemical and Biophysical Research Communications
  6. Mechanisms of immune system activation in mammalians by small interfering RNA (siRNA)
    Behzad Mansoori, Ali Mohammadi, Solmaz Shirjang, Behzad Baradaran · 2015 · Artificial Cells Nanomedicine and Biotechnology
  7. Rapid and Efficient Conversion of Integration-Free Human Induced Pluripotent Stem Cells to GMP-Grade Culture Conditions
    Jens Durruthy-Durruthy, Sharon F. Briggs, Jason P. Awe, Cyril Y. Ramathal, Saravanan Karumbayaram, Patrick C. Lee, Julia D. Heidmann, Amander T. Clark, Ioannis Karakikes, Kyle M. Loh et al. · 2014 · PLoS ONE
  8. Corticosteroids and cellulose purification improve, respectively, the in vivo translation and vaccination efficacy of sa-mRNAs
    Zhong, Zifu, McCafferty, Séan, Opsomer, Lisa, Wang, Haixiu, Huysmans, Hanne, De Temmerman, Joyca, Lienenklaus, Stefan, Portela Catani, João Paulo, Combes, Francis, Sanders, Niek N. · 2021 · Molecular Therapy
  9. Synthetic mRNAs for manipulating cellular phenotypes: an overview
    Elgar Susanne Quabius, Guido Krupp · 2014 · New Biotechnology
  10. Structural components for amplification of positive and negative strand VEEV splitzicons
    Blakney, Anna K., McKay, Paul F., Shattock, Robin J. · 2018 · Frontiers in Molecular Biosciences
  11. The cytotoxic and immunogenic hurdles associated with non-viral mRNA-mediated reprogramming of human fibroblasts
    Katharina Drews, Geertrui Tavernier, Joseph Demeester, Hans Rudolf Lehrach, Stefaan C. De Smedt, Joanna Rejman, James Adjaye · 2012 · Biomaterials
  12. Preclinical evaluation of an mRNA HIV vaccine combining rationally selected antigenic sequences and adjuvant signals (HTI-TriMix)
    Alberto Crespo Guardo, Patrick Tjok Joe, Laia Miralles, Manel Enric Bargalló, Beatriz Mothe, Ahmet Krasniqi, Carlo Heirman, Felipe García, Kris Thielemans, Christian Brander et al. · 2016 · AIDS
  13. Production of pure and functional RNA for in vitro reconstitution experiments
    Franziska Theresia Edelmann, Annika Niedner, Dierk Niessing · 2013 · Methods
  14. Differential Kinetics of Antigen Dependency of CD4+ and CD8+ T Cells
    Hannah Rabenstein, Anne C. Behrendt, Joachim W. Ellwart, Ronald Naumann, Marion Horsch, Johannes Beckers, Reinhard Obst · 2014 · The Journal of Immunology
  15. Strong anion-exchange fast performance liquid chromatography as a versatile tool for preparation and purification of RNA produced by in vitro transcription
    Jiří Koubek, Ku Feng Lin, Yet‐Ran Chen, Richard Ping Cheng, Joseph Jen‐Tse Huang · 2013 · RNA
  16. The role of type I interferons in CD4+ T cell differentiation
    Mirela Kuka, Marco De Giovanni, Matteo Iannacone · 2019 · Immunology Letters
  17. Efficient inhibition of RNA self-primed extension by addition of competing 3′-capture DNA-improved RNA synthesis by T7 RNA polymerase
    Yasaman Gholamalipour, William C. Johnson, Craig T. Martin · 2019 · Nucleic Acids Research
  18. DSRNA and the Innate Antiviral Immune Response
    Stephanie J. DeWitte‐Orr, Karen Louise Mossman · 2010 · Future Virology
  19. Recombinant Vaccinia virus-coded interferon inhibitor B18R: Expression, refolding and a use in a mammalian expression system with a RNA-vector
    Yuriy G. Kim, Aliya Zh. Baltabekova, E. Zhiyenbay, A. S. Aksambayeva, Zhadyra Sagykyzy Shagyrova, Rinat A Khannanov, Erlan M. Ramanculov, Alexandr V. Shustov · 2017 · PLoS ONE
  20. All-human microphysical model of metastasis therapy
    Sarah Wheeler, Jeffrey T. Borenstein, Amanda M. Clark, Mo R. Ebrahimkhani, Ira J. Fox, Linda Gay Griffith, Walker Inman, Douglas A. Lauffenburger, Transon Nguyen, Venkateswaran C. Pillai et al. · 2013 · Stem Cell Research & Therapy
  21. Structural Biology of NOD-Like Receptors
    Xinru Yang, Guangzhong Lin, Zhifu Han, Jijie Chai · 2019 · Advances in experimental medicine and biology
  22. Analysis of an Interaction between the Soluble Vaccinia Virus-Coded Type I Interferon (IFN)-Receptor and Human IFN-α1 and IFN-α2
    Hana Liptáková, Eva Kontseková, Antonio Alcamı́, Geoffrey L. Smith, PETER KONTSEK · 1997 · Virology
  23. Therapeutic Vaccine in Chronically HIV-1-Infected Patients: A Randomized, Double-Blind, Placebo-Controlled Phase IIa Trial with HTI-TriMix
    Wesley de Jong, Lorna Leal, Jozefien Buyze, Pieter Pannus, Alberto Crespo Guardo, María Salgado, Beatriz Mothe, José Moltó, Sara Morón‐López, Cristina Gálvez et al. · 2019 · Vaccines
  24. Template‐free generation of RNA species that replicate with bacteriophage T7 RNA polymerase.
    Christof Κ. Biebricher, Rüdiger Luce · 1996 · The EMBO Journal
  25. RNAimmuno: A database of the nonspecific immunological effects of RNA interference and microRNA reagents
    Marta Olejniczak, Paulina Galka-Marciniak, Katarzyna Polak, Andrzej Fligier, Włodzimierz J. Krzyżosiak · 2012 · RNA
  26. HIV-1–Triggered Release of Type I IFN by Plasmacytoid Dendritic Cells Induces BAFF Production in Monocytes
    Alejandro M Gomez, Michel Ouellet, Michel J. Tremblay · 2015 · The Journal of Immunology
  27. The Modified Vaccination Technique
    A. Z. Barabas, Chad Douglas Cole, Zoltan Kovacs, Erno I. Kovacs, René Lafrenière · 2018 · Vaccines
  28. The Role of α1-Microglobulin (A1M) in Erythropoiesis and Erythrocyte Homeostasis—Therapeutic Opportunities in Hemolytic Conditions
    Amanda Kristiansson, Magnus Gram, Johan Flygare, Stefan Rocco Hansson, Bo Åkerström, Jill R. Storry · 2020 · International Journal of Molecular Sciences
  29. mPEG-PLGA Nanoparticles Labelled with Loaded or Conjugated Rhodamine-B for Potential Nose-to-Brain Delivery
    E. F. Craparo, T. Musumeci, A. Bonaccorso, R. Pellitteri, Alessia Romeo, Irina Naletova, L. Cucci, G. Cavallaro, C. Satriano · 2021 · Pharmaceutics
  30. Comparison of the Expression Kinetics and Immunostimulatory Activity of Replicating mRNA, Nonreplicating mRNA, and pDNA after Intradermal Electroporation in Pigs
    Bregje Leyman, Hanne Huysmans, Séan Mc Cafferty, Francis Combes, Eric Cox, Bert Devriendt, Niek N. Sanders · 2018 · Molecular Pharmaceutics
  31. Inhibition of the Inflammatory Pathway Enhances Both the in Vitro and in Vivo Transfection Activity of Exogenous in Vitro-Transcribed mRNAs Delivered by Lipid Nanoparticles
    Takara Ohto, Manami Konishi, Hiroki Tanaka, Koji Onomoto, Mitsutoshi Yoneyama, Yuta Nakai, Kota Tange, Hiroki Yoshioka, Hidetaka Akita · 2019 · Biological and Pharmaceutical Bulletin
  32. Structures of RIG-I-Like Receptors and Insights into Viral RNA Sensing
    Xiaojiao Fan, Tengchuan Jin · 2019 · Advances in experimental medicine and biology
  33. Synthetic Messenger RNA and Cell Metabolism Modulation
    Peter M. Rabinovich · 2013 · Methods in molecular biology
  34. Strategies for modulating innate immune activation and protein production of in vitro transcribed mRNAs
    Kristin H. Loomis, Jonathan L. Kirschman, Sushma M. Bhosle, Ravi V. Bellamkonda, Philip J. Santangelo · 2015 · Journal of Materials Chemistry B
  35. Messenger RNA translation enhancement by immune evasion proteins: a comparative study between EKB (vaccinia virus) and NS1 (influenza A virus)
    Yi Liu, Jas Min Chin, En Lin Choo, Kyle K.L. Phua · 2019 · Scientific Reports
  36. A method for stabilizing RNA for transfection that allows control of expression duration
    Toshinori Hayashi, Deepak A. Lamba, Amber D. Slowik, Thomas A. Reh, Olivia Bermingham‐McDonogh · 2010 · Developmental Dynamics
  37. Non-linear enhancement of mRNA delivery efficiencies by influenza A derived NS1 protein engendering host gene inhibition property
    Kyle K.L. Phua, Yi Liu, Shun Hui Sim · 2017 · Biomaterials
  38. Efficient reduction of synthetic mRNA induced immune activation by simultaneous delivery of B18R encoding mRNA
    Tatjana Michel, Sonia Golombek, Heidrun Steinle, Ludmilla Hann, Ana Velić, Boris Maček, Stefanie Krajewski, Christian Schlensak, Hans Peter Wendel, Meltem Avci‐Adali · 2019 · Journal of Biological Engineering
  39. RNA-based vaccines and innate immune activation: Not too hot and not too cold
    Robert Frederickson, Roland W. Herzog · 2021 · Molecular Therapy
  40. BAY11 enhances OCT4 synthetic mRNA expression in adult human skin cells
    Jason P. Awe, Agustin Vega Crespo, You Li, Megerditch Kiledjian, James Byrne · 2013 · Stem Cell Research & Therapy
  41. IFN-β-specific signaling via a unique IFNAR1 interaction
    Surinder Kaur, Leonidas C. Platanias · 2013 · Nature Immunology
  42. An Annis Mirabilis for the Molecular Therapy Journal Family
    Robert Frederickson, Roland W. Herzog · 2020 · Molecular Therapy
  43. Immune Evasion by Viruses
    R. A. Simmons, Christian B. Willberg, Paul Klenerman · 2013 · Encyclopedia of Life Sciences
  44. The Role of Il-12 and Type I Interferon in Governing the Magnitude of CD8 T Cell Responses
    Gabriel R. Starbeck-Miller, John T. Harty · 2015 · Advances in experimental medicine and biology
  45. Suppression of mRNA Nanoparticle Transfection in Human Fibroblasts by Selected Interferon Inhibiting Small Molecule Compounds
    Yang Liu, Manoj N. Krishnan, Kyle K.L. Phua · 2017 · Biomolecules
  46. Modulation of mRNA Translation and Cell Viability by Influenza A Virus Derived Nonstructural Protein 1
    Yi Liu, Zhen Hua Chia, Johannes Nathaniel Min Hui Liew, Shi Min Or, Kyle K.L. Phua · 2018 · Nucleic Acid Therapeutics
  47. Leap-In Transposases and Transposons Accelerate Cell Line Development
    Maggie Lee, Claudia Sepulveda, Calvin Tang, Vivi Truong, Divya Teja Vavilala, Lynn Webster, Bo Zhang, Ferenc L. Boldog · 2019 · Genetic Engineering & Biotechnology News
  48. The influenza virus PB1-F2 protein has interferon-antagonistic activity
    Sabine Eva Dudek, Ludmilla Wixler, Carolin Nordhoff, Alexandra Nordmann, Darisuren Anhlan, Viktor Wixler, Stephan Ludwig · 2011 · Biological Chemistry
  49. RNA Epitranscriptome: Role of the 5' Cap
    Anton P. McCaffrey · 2019 · Genetic Engineering & Biotechnology News
  50. 3D-tips: user-friendly mesh barrier pipette tips for 3D-spheroid culture
    Mo Chen, Marie‐Laure Vial, James A. St John · 2019 · Journal of Biological Engineering
  51. Vaccinia Virus Protein B18R: Influence on mRNA Immunogenicity and Translation upon Non-Viral Delivery in Different Ocular Cell Types
    An‐Katrien Minnaert, Joke Devoldere, Karen Peynshaert, Laure Vercruysse, Stefaan C. De Smedt, Katrien Remaut · 2021 · Pharmaceutics
  52. Expression of the Vaccinia Virus Antiapoptotic F1 Protein Is Blocked by Protein Kinase R in the Absence of the Viral E3 Protein
    Ninad Mehta, Emeka K. Enwere, Theodore dos Santos, Holly A. Saffran, Bart Hazes, David H. Evans, Michele Barry, James R. Smiley · 2018 · Journal of Virology