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Cited by 164Congenital Heart Disease StudiesCongenital heart defects researchCardiovascular Conditions and Treatments

The DOI matches its Crossref record; 24 of the 25 references it cites were found in a registry or an index.

Birth prevalence of congenital heart defects in Norway 1994-2009—A nationwide study

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Leirgul, Elisabeth, Fomina, Tatiana, Brodwall, Kristoffer, Greve, Gottfried, Holmstrøm, Henrik, Vollset, Stein Emil, Tell, Grethe S., Øyen, Nina·2014·American Heart Journal
DOI 10.1016/j.ahj.2014.07.030
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Abstract

BACKGROUND: The reasons for decreasing birth prevalence of congenital heart defects (CHDs) in several European countries and Canada are not fully understood. We present CHD prevalence among live births, stillbirths, and terminated pregnancies in an entire nation over a period of 16 years. METHODS: Information on all births in the Medical Birth Registry of Norway, 1994-2009, was updated with information on CHD from the hospitals' Patient Administrative Systems, the National Hospital's clinical database for children with heart disease, and the Cause of Death Registry. Individuals with heart defects were assigned specific cardiac phenotypes. RESULTS: Among 954,413 births, 13,081 received a diagnosis of CHD (137.1 per 10,000 births, 133.2 per 10,000 live births). The prevalence per 10,000 births was as follows: heterotaxia, 1.6; conotruncal defects, 11.6; atrioventricular septal defects, 5.6; anomalous pulmonary venous return, 1.1; left outflow obstructions, 8.7; right outflow obstructions, 5.6; septal defects, 65.5; isolated patent ductus arteriosus, 24.6; and other specified or unspecified CHD, 12.7. Excluding preterm patent ductus arteriosus, the CHD prevalence was 123.4 per 10,000; per year, the prevalence increased with 3.5% (95% CI 2.5-4.4) in 1994-2005 and declined with 9.8% (-16.7 to -2.4) from 2005 onwards. Severe CHD prevalence was 30.7 per 10,000; per-year increase was 2.3% (1.1-3.5) in 1994-2004, and per-year decrease was 3.4% (-6.6 to -0.0) in 2004-2009. Numbers included severe CHD in stillbirths and terminated pregnancies. CONCLUSIONS: The birth prevalence of CHD declined from around 2005. Specifically, the prevalence of severe CHD was reduced by 3.4% per year from 2004 through 2009.

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Metadata

Authors
Leirgul, E., Fomina, T., Brodwall, K., Greve, G., Holmstrøm, H., Vollset, S. E., Tell, G. S., & Øyen, N.
Affiliations
  • Haukeland University Hospital (NO)
  • University of Bergen (NO)
  • Oslo University Hospital (NO)
  • Norwegian Institute of Public Health (NO)
Corresponding author
Leirgul, Elisabeth
ORCID
Venue
American Heart Journal
Publisher
Elsevier BV
Published
2014-12
Volume
168
Issue
6
Pages
956-964
ISSN
0002-8703 (ISSN-L)
DOI
10.1016/j.ahj.2014.07.030
OpenAlex
W2160481214
Cited by
164
References
25
Citations by year
2026: 9 · 2025: 19 · 2024: 13 · 2023: 17 · 2022: 19 · 2021: 14 · 2020: 10 · 2019: 17 · 2018: 17 · 2017: 11 · 2016: 13 · 2015: 5
FWCI
7.32
Type
journal article
Language
en
Open access
Licence
Locations
  • American Heart Journal (publishedVersion, cc-by-nc-nd)
  • PubMed (publishedVersion)
  • NORA - Norwegian Open Research Archives (submittedVersion, cc-by-nc-nd)
Topics
  • Health Sciences › Medicine › Cardiology and Cardiovascular Medicine › Congenital Heart Disease Studies
  • Life Sciences › Biochemistry, Genetics and Molecular Biology › Molecular Biology › Congenital heart defects research
  • Health Sciences › Medicine › Pediatrics, Perinatology and Child Health › Cardiovascular Conditions and Treatments
Keywords
congenital heart disease, birth prevalence, secular trends, stillbirth, patent ductus arteriosus, conotruncal defects, atrioventricular septal defect, heterotaxia, anomalous pulmonary venous return, septal defects, Norway, Medical Birth Registry of Norway, cardiac phenotype, severe congenital heart disease
MeSH terms
Birth Certificates, Female, Heart Defects, Congenital, Humans, Infant, Newborn, Male, Norway, Pregnancy, Registries, Prevalence

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