ED overcrowding is associated with an increased frequency of medication errors
Abstract
Objectives Despite the growing problems of emergency department (ED) crowding, the potential impact on the frequency of medication errors occurring in the ED is uncertain. Using a metric to measure ED crowding in real time (the Emergency Department Work Index, or EDWIN, score), we sought to prospectively measure the correlation between the degree of crowding and the frequency of medication errors occurring in our ED as detected by our ED pharmacists.Methods We performed a prospective, observational study in a large, community hospital ED of all patients whose medication orders were evaluated by our ED pharmacists for a 3-month period. Our ED pharmacists review the orders of all patients in the ED critical care section and the Chest Pain unit, and all admitted patients boarding in the ED. We measured the Spearman correlation between average daily EDWIN score and number of medication errors detected and determined the score's predictive performance with receiver operating characteristic (ROC) curves.Results A total of 283 medication errors were identified by the ED pharmacists over the study period. Errors included giving medications at incorrect doses, frequencies, durations, or routes and giving contraindicated medications. Error frequency showed a positive correlation with daily average EDWIN score (Spearman's rho = 0.33; P = .001). The area under the ROC curve was 0.67 (95% confidence interval, 0.56-0.78) with failure defined as greater than 1 medication error per day.Conclusions We identified an increased frequency of medication errors in our ED with increased crowding as measured with a real-time modified EDWIN score.
Integrity signals
Registry
Cites
Statistics
Claims the paper makes
Claims other papers make about this one
Each is checked against this paper’s own text: does it say what the citing paper says it does?
A recent study found a link between ED overcrowding and medication errors.
“Indeed, a recent study found a link between ED overcrowding and medication errors [91].”
From Lean Thinking in Emergency Departments: A Critical Review (2011) · cites this paper as [91]
Cites
Institute of Medicine (2000) · National Academies Press eBooks · doi:10.17226/9728 · Cited by 14,174 · see citing works
Wall, A. (2000) · British Journal of Healthcare Management · doi:10.12968/bjhc.2000.6.9.19311 · Cited by 5,909 · see citing works
The Nature of Adverse Events in Hospitalized Patients
Leape, L. L., Brennan, T. A., Laird, N. M., Lawthers, A. G., Localio, A. R., Barnes, B. A., Hebert, L. E., Newhouse, J. P., Weiler, P. C., & Hiatt, H. H. (1991) · New England Journal of Medicine · doi:10.1056/nejm199102073240605 · Cited by 3,766 · see citing works
Systematic Review of Emergency Department Crowding: Causes, Effects, and Solutions
Hoot, N. R., & Aronsky, D. (2008) · Annals of Emergency Medicine · doi:10.1016/j.annemergmed.2008.03.014 · Cited by 1,689 · see citing works
Systems Analysis of Adverse Drug Events
Leape, L. L. (1995) · JAMA: The Journal of the American Medical Association · doi:10.1001/jama.1995.03530010049034 · Cited by 1,404 · see citing works
To err is human. Building a safer health system
Marano, C., Murianni, L., & Sticchi, L. (2005) · Italian Journal of Public Health · doi:10.2427/5972 · Cited by 1,285 · see citing works
Overcrowding in the nation’s emergency departments: Complex causes and disturbing effects
Derlet, R. W., & Richards, J. R. (2000) · Annals of Emergency Medicine · doi:10.1016/s0196-0644(00)70105-3 · Cited by 1,052 · see citing works
Trzeciak, S., & Rivers, E. (2003) · Emergency Medicine Journal · doi:10.1136/emj.20.5.402 · Cited by 841 · see citing works
Increase in patient mortality at 10 days associated with emergency department overcrowding
Richardson, D. B. (2006) · The Medical Journal of Australia · doi:10.5694/j.1326-5377.2006.tb00204.x · Cited by 829 · see citing works
Sprivulis, P., Silva, J. D., Jacobs, I. G., Jelinek, G. A., & Frazer, A. R. L. (2006) · The Medical Journal of Australia · doi:10.5694/j.1326-5377.2006.tb00203.x · Cited by 760 · see citing works
Sprivulis, P., Silva, J. D., Jacobs, I. G., Frazer, A. R. L., & Jelinek, G. A. (2006) · The Medical Journal of Australia · doi:10.5694/j.1326-5377.2006.tb00416.x · Cited by 757 · see citing works
Chisholm, C. D., Collison, E. K., Nelson, D. R., & Cordell, W. H. (2000) · Academic Emergency Medicine · doi:10.1111/j.1553-2712.2000.tb00469.x · Cited by 610 · see citing works
The Potential for Improved Teamwork to Reduce Medical Errors in the Emergency Department
Risser, D. T., Rice, M., Salisbury, M. L., Simon, R., Jay, G. D., & Berns, S. D. (1999) · Annals of Emergency Medicine · doi:10.1016/s0196-0644(99)70134-4 · Cited by 559 · see citing works
Reliability and Validity of a New Five‐level Triage Instrument
Wuerz, R. C., Milne, L. W., Eitel, D. R., Travers, D., & Gilboy, N. (2000) · Academic Emergency Medicine · doi:10.1111/j.1553-2712.2000.tb01066.x · Cited by 554 · see citing works
Emergency department crowding and thrombolysis delays in acute myocardial infarction
Schull, M. J., Vermeulen, M. J., Slaughter, G., Morrison, L. J., & Daly, P. (2004) · Annals of Emergency Medicine · doi:10.1016/j.annemergmed.2004.05.004 · Cited by 402 · see citing works
Horwitz, L. I., Meredith, T., Schuur, J. D., Shah, N., Kulkarni, R. G., & Jenq, G. Y. (2008) · Annals of Emergency Medicine · doi:10.1016/j.annemergmed.2008.05.007 · Cited by 306 · see citing works
Emergency medicine: A practice prone to error?
Croskerry, P., & Sinclair, D. E. (2001) · Canadian Journal of Emergency Medicine · doi:10.1017/s1481803500005765 · Cited by 267 · see citing works
Crisis in the emergency department
Kellermann, A. L. (2006) · New England Journal of Medicine · doi:10.1056/nejmp068194 · Cited by 264 · see citing works
Fee, C. R., Weber, E. J., Maak, C. A., & Bacchetti, P. (2007) · Annals of Emergency Medicine · doi:10.1016/j.annemergmed.2007.08.003 · Cited by 257 · see citing works
Decreased health care quality associated with emergency department overcrowding
Miró, Ò., Antonio, M. T.-S., JIMÉNEZ, S., DIOS, A. D., Sánchez, M. Á. C., BORRÁS, A., & Milla, J. J. P. (1999) · European Journal of Emergency Medicine · doi:10.1097/00063110-199906000-00003 · Cited by 250 · see citing works
Errors in a busy emergency department
Fordyce, J., Blank, F. S. J., Pekow, P. S., Smithline, H. A., Ritter, G., Gehlbach, S. H., Benjamin, E. M., & Henneman, P. L. (2003) · Annals of Emergency Medicine · doi:10.1016/s0196-0644(03)00398-6 · Cited by 247 · see citing works
Olshaker, J. S., & Rathlev, N. K. (2006) · Journal of Emergency Medicine · doi:10.1016/j.jemermed.2005.05.023 · Cited by 239 · see citing works
Pines, J. M., Hollander, J. E., Localio, A. R., & Metlay, J. P. (2006) · Academic Emergency Medicine · doi:10.1197/j.aem.2006.03.568 · Cited by 231 · see citing works
Development and Validation of a New Index to Measure Emergency Department Crowding
Bernstein, S. L., Verghese, V., Leung, W., Lunney, A. T., & Perez, I. (2003) · Academic Emergency Medicine · doi:10.1111/j.1553-2712.2003.tb00647.x · Cited by 211 · see citing works
Impact of emerging technologies on medication errors and adverse drug events
Oren, E., Shaffer, E. R., & Guglielmo, B. J. (2003) · American Journal of Health-System Pharmacy · doi:10.1093/ajhp/60.14.1447 · Cited by 190 · see citing works
The Emergency Department Occupancy Rate: A Simple Measure of Emergency Department Crowding?
McCarthy, M. L., Aronsky, D., Jones, I. D., Miner, J. R., Band, R. A., Baren, J. M., Desmond, J. S., Baumlin, K. M., Ding, R., & Shesser, R. F. (2007) · Annals of Emergency Medicine · doi:10.1016/j.annemergmed.2007.09.003 · Cited by 180 · see citing works
Promoting Patient Safety and Preventing Medical Error in Emergency Departments
Schenkel, S. M. (2000) · Academic Emergency Medicine · doi:10.1111/j.1553-2712.2000.tb00466.x · Cited by 150 · see citing works
Emergency Department Overcrowding in Florida, New York, and Texas
Derlet, R. W., & Richards, J. R. (2002) · Southern Medical Journal · doi:10.1097/00007611-200295080-00013 · Cited by 125 · see citing works
An Independent Evaluation of Four Quantitative Emergency Department Crowding Scales
Jones, S. S., Allen, T. L., Flottemesch, T. J., et al. (2006) · Academic Emergency Medicine · doi:10.1197/j.aem.2006.05.021 · Cited by 124 · see citing works
Gordon, J. A., Billings, J., Asplin, B. R., & Rhodes, K. V. (2001) · Academic Emergency Medicine · doi:10.1111/j.1553-2712.2001.tb01110.x · Cited by 115 · see citing works
Care in the Emergency Department: How Crowded Is Overcrowded?
Hwang, U., & Concato, J. (2004) · Academic Emergency Medicine · doi:10.1197/j.aem.2004.07.004 · Cited by 113 · see citing works
Weiss, S. J., Ernst, A. A., & Nick, T. G. (2006) · Academic Emergency Medicine · doi:10.1197/j.aem.2005.12.009 · Cited by 113 · see citing works
Emergency Department Overcrowding in Florida, New York, and Texas
Derlet, R. W., & Richards, J. R. (2002) · Southern Medical Journal · doi:10.1097/00007611-200208000-00012 · Cited by 107 · see citing works
Profiles in Patient Safety: Medication Errors in the Emergency Department
Croskerry, P., Shapiro, M. J., Campbell, S. G., LeBlanc, C. H., Sinclair, D. E., Wren, P., & Marcoux, M. (2004) · Academic Emergency Medicine · doi:10.1111/j.1553-2712.2004.tb02214.x · Cited by 99 · see citing works
A framework for classifying factors that contribute to error in the emergency department
Cosby, K. S. (2003) · Annals of Emergency Medicine · doi:10.1016/s0196-0644(03)00635-8 · Cited by 91 · see citing works
Medication Errors Among Acutely Ill and Injured Children Treated in Rural Emergency Departments
Marcin, J. P., Dharmar, M., Cho, M., Seifert, L. L., Cook, J. L., Cole, S. L., Nasrollahzadeh, F., & Romano, P. S. (2007) · Annals of Emergency Medicine · doi:10.1016/j.annemergmed.2007.01.020 · Cited by 90 · see citing works
Human Error in Emergency Medicine
Wears, R. L., & Leape, L. L. (1999) · Annals of Emergency Medicine · doi:10.1016/s0196-0644(99)70133-2 · Cited by 83 · see citing works
Medication errors in the emergency department
Peth, H. A. (2003) · Emergency Medicine Clinics of North America · doi:10.1016/s0733-8627(02)00085-8 · Cited by 79 · see citing works
Hobgood, C., Xie, J., Weiner, B. J., & Hooker, J. S. (2004) · Academic Emergency Medicine · doi:10.1111/j.1553-2712.2004.tb01435.x · Cited by 75 · see citing works
Patient Concerns about Medical Errors in Emergency Departments
Burroughs, T. E. (2005) · Academic Emergency Medicine · doi:10.1197/j.aem.2004.08.052 · Cited by 74 · see citing works
Development of an Emergency Department Work Score to Predict Ambulance Diversion
Epstein, S. K., & Tian, L. (2006) · Academic Emergency Medicine · doi:10.1197/j.aem.2005.11.081 · Cited by 72 · see citing works
Defining, Identifying, and Measuring Error in Emergency Medicine
Handler, J. A., Gillam, M. P., Sanders, A. B., et al. (2000) · Academic Emergency Medicine · doi:10.1111/j.1553-2712.2000.tb00462.x · Cited by 71 · see citing works
Kozer, E., Berkovitch, M., & Koren, G. (2006) · Pediatric Clinics of North America · doi:10.1016/j.pcl.2006.09.005 · Cited by 63 · see citing works
Emergency Physicians and Disclosure of Medical Errors
Moskop, J. C., Geiderman, J. M., Hobgood, C., & Larkin, G. L. (2006) · Annals of Emergency Medicine · doi:10.1016/j.annemergmed.2006.04.007 · Cited by 52 · see citing works
The Boarders in the Emergency Department (BED) study
Gilligan, P., Winder, S., Singh, I., et al. (2008) · Emergency Medicine Journal · doi:10.1136/emj.2007.048173 · Cited by 49 · see citing works
An Independent Evaluation of Four Quantitative Emergency Department Crowding Scales
Jones, S. S., Allen, T. L., Flottemesch, T. J., et al. (2006) · Academic Emergency Medicine · doi:10.1111/j.1553-2712.2006.tb01649.x · Cited by 48 · see citing works
Care in the Emergency Department: How Crowded Is Overcrowded?
Hwang, U., & Concato, J. (2004) · Academic Emergency Medicine · doi:10.1111/j.1553-2712.2004.tb00686.x · Cited by 40 · see citing works
Errors in Emergency Medicine A Call to Action
Biros, M. H., Adams, J. G., & Wears, R. L. (2000) · Academic Emergency Medicine · doi:10.1111/j.1553-2712.2000.tb00456.x · Cited by 36 · see citing works
Human error in medicine: Promise and pitfalls, part 2
Wears, R. L., Janiak, B. D., Moorhead, J. C., et al. (2000) · Annals of Emergency Medicine · doi:10.1067/mem.2000.108713 · Cited by 34 · see citing works
Patient Concerns about Medical Errors in Emergency Departments
Burroughs, T. E., Waterman, A. D., Gallagher, T. H., et al. (2005) · Academic Emergency Medicine · doi:10.1111/j.1553-2712.2005.tb01480.x · Cited by 34 · see citing works
Beyond “Communication Failure”
Patterson, E. S., & Wears, R. L. (2008) · Annals of Emergency Medicine · doi:10.1016/j.annemergmed.2008.07.014 · Cited by 31 · see citing works
Hobgood, C. (2004) · Academic Emergency Medicine · doi:10.1197/j.aem.2003.08.020 · Cited by 31 · see citing works
The Effect of Clinical Experience on the Error Rate of Emergency Physicians
Berk, W. A., Welch, R. D., Levy, P. D., Jones, J. T., Arthur, C., Kuhn, G. J., King, J. J., Bock, B. F., & Sweeny, P. J. (2008) · Annals of Emergency Medicine · doi:10.1016/j.annemergmed.2008.01.329 · Cited by 30 · see citing works
Reducing Medication Errors: A Regional Approach for Hospitals
McCarter, T. G., Centafont, R., Daly, F. N., Kokoricha, T., & Leander Po, J. Z. (2003) · Drug Safety · doi:10.2165/00002018-200326130-00003 · Cited by 30 · see citing works
Human error in medicine: Promise and pitfalls, part 1
Wears, R. L., Janiak, B. D., Moorhead, J. C., Kellermann, A. L., Yeh, C. S., Rice, M., Jay, G. D., Perry, S. J., & Woolard, R. H. (2000) · Annals of Emergency Medicine · doi:10.1067/mem.2000.aem36158 · Cited by 30 · see citing works
Cb, E., & Wiebe, C. (1989) · PubMed · Cited by 29 · see citing works
EMDOC (Emergency Department Overcrowding) Internet-Based Safety Net Research
Steele, R. J., & Kiss, A. (2007) · Journal of Emergency Medicine · doi:10.1016/j.jemermed.2007.03.022 · Cited by 26 · see citing works
Development of an Emergency Department Work Score to Predict Ambulance Diversion
Epstein, S. K., & Tian, L. (2006) · Academic Emergency Medicine · doi:10.1111/j.1553-2712.2006.tb00320.x · Cited by 26 · see citing works
Decrease in medical command errors with use of a “standing orders” protocol system
Holliman, C. J., Wuerz, R. C., & Meador, S. A. (1994) · The American Journal of Emergency Medicine · doi:10.1016/0735-6757(94)90138-4 · Cited by 22 · see citing works
Errors in Emergency Medicine Research Strategies
Kyriacou, D. N., & Coben, J. H. (2000) · Academic Emergency Medicine · doi:10.1111/j.1553-2712.2000.tb00465.x · Cited by 22 · see citing works
Patient Misidentification in a Pediatric Emergency Department
O’Neill, K. E., Shinn, D., Starr, K. T., et al. (2004) · Pediatric Emergency Care · doi:10.1097/01.pec.0000136895.99271.86 · Cited by 18 · see citing works
Overcrowding: Not Just an Emergency Department Issue
Howard, P. K. (2005) · Journal of Emergency Nursing · doi:10.1016/j.jen.2005.04.005 · Cited by 18 · see citing works
Medical Errors and Emergency Medicine: Will the Difficult Questions Be Asked, and Answered?
Feldman, J. A. (2003) · Academic Emergency Medicine · doi:10.1111/j.1553-2712.2003.tb00641.x · Cited by 16 · see citing works
The Error of Counting “Errors”
Wears, R. L. (2008) · Annals of Emergency Medicine · doi:10.1016/j.annemergmed.2008.03.015 · Cited by 13 · see citing works
The epidemiology of medication prescribing errors in the emergency department.
Jenkins, G., Johnston, P. E., Patel, N., et al. (2006) · PubMed · Cited by 12 · see citing works
Flagged first, then by citations
Cited by
Sorted by citations
Emergency department crowding: A systematic review of causes, consequences and solutions
Morley, C., Unwin, M., Peterson, G. M., Stankovich, J., & Kinsman, L. (2018) · PLOS ONE · doi:10.1371/journal.pone.0203316 · Cited by 1,386 · see citing works
Lean Thinking in Emergency Departments: A Critical Review
Holden, R. J. (2011) · Annals of Emergency Medicine · doi:10.1016/j.annemergmed.2010.08.001 · Cited by 516 · see citing works
Arya, R., Wei, G., McCoy, J. V., Crane, J., Ohman-Strickland, P., & Eisenstein, R. M. (2013) · Academic Emergency Medicine · doi:10.1111/acem.12249 · Cited by 78 · see citing works
- Authors
- Kulstad, E. B., Sikka, R., Sweis, R. T., Kelley, K. M., & Rzechula, K. H.
- Affiliations
- Advocate Christ Medical Center (US)
- Corresponding author
- Kulstad, Erik B.
- Venue
- The American Journal of Emergency Medicine
- Publisher
- Elsevier BV
- Published
- 2010-03
- Volume
- 28
- Issue
- 3
- Pages
- 304-309
- ISSN
- 0735-6757 (ISSN-L)
- OpenAlex
- W2065846709
- Cited by
- 306
- References
- 65
- Citations by year
- 2026: 6 · 2025: 29 · 2024: 26 · 2023: 30 · 2022: 16 · 2021: 23 · 2020: 27 · 2019: 25 · 2018: 19 · 2017: 13 · 2016: 16 · 2015: 20 · 2014: 25 · 2013: 10 · 2012: 7
- FWCI
- 9.42
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- The American Journal of Emergency Medicine (publishedVersion)
- PubMed (publishedVersion)
- Topics
- Health Sciences › Medicine › Emergency Medicine › Emergency and Acute Care Studies
- Health Sciences › Health Professions › Emergency Medical Services › Patient Safety and Medication Errors
- Health Sciences › Medicine › Geriatrics and Gerontology › Pharmaceutical Practices and Patient Outcomes
- Keywords
- emergency department overcrowding, medication errors, medication order review, contraindicated medications, dosing errors
- MeSH terms
- Crowding, Emergency Service, Hospital, Humans, Medication Errors, Pharmacy Service, Hospital, Prospective Studies, ROC Curve
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
Are you an author, or do you see a problem with this page? Request a review