Improvement of nasal airway ventilation after rapid maxillary expansion evaluated with computational fluid dynamics
Abstract
Introduction Rapid maxillary expansion is known to improve nasal airway ventilation. However, it is difficult to precisely evaluate this improvement with conventional methods. The purpose of this longitudinal study was to use computational fluid dynamics to estimate the effect of rapid maxillary expansion.Methods Twenty-three subjects (9 boys, 14 girls; mean ages, 9.74 ± 1.29 years before rapid maxillary expansion and 10.87 ± 1.18 years after rapid maxillary expansion) who required rapid maxillary expansion as part of their orthodontic treatment had cone-beam computed tomography images taken before and after rapid maxillary expansion. The computed tomography data were used to reconstruct the 3-dimensional shape of the nasal cavity. Two measures of nasal airflow function (pressure and velocity) were simulated by using computational fluid dynamics.Results The pressure after rapid maxillary expansion (80.55 Pa) was significantly lower than before rapid maxillary expansion (147.70 Pa), and the velocity after rapid maxillary expansion (9.63 m/sec) was slower than before rapid maxillary expansion (13.46 m/sec).Conclusions Improvement of nasal airway ventilation by rapid maxillary expansion was detected by computational fluid dynamics.
Integrity signals
Registry
Cites
Statistics
Claims the paper makes
Claims other papers make about this one
Each is checked against this paper’s own text: does it say what the citing paper says it does?
Studies specifically assessing long-term effects in pediatric populations remain scarce.
“Studies specifically assessing long-term effects in pediatric populations remain scarce [12, 15, 44]”
From Long-Term Changes Following Orthopedic Mandibular Advancement Therapy in Pediatric Obstructive Sleep Apnea: a 7-Year Follow-up Study (2026) · cites this paper as [15]
Cites
André, R. F., Vuyk, H. D., Ahmed, A., Graamans, K., & Trenité, G. J. N. (2009) · Clinical Otolaryngology · doi:10.1111/j.1749-4486.2009.02042.x · Cited by 319 · see citing works
Garib, D. G., Henriques, J. F. C., Janson, G., et al. (2005) · PubMed · doi:10.1043/0003-3219(2005)75[548:rmetvt]2.0.co;2 · Cited by 307 · see citing works
Chung, C., & Font, B. (2004) · American Journal of Orthodontics and Dentofacial Orthopedics · doi:10.1016/j.ajodo.2003.10.035 · Cited by 277 · see citing works
Changes in nasal airway resistance associated with rapid maxillary expansion
Hershey, H. G., Stewart, B. L., & Warren, D. W. (1976) · American Journal of Orthodontics · doi:10.1016/0002-9416(76)90076-2 · Cited by 248 · see citing works
Kim, Y.-J., Hong, J.-S., Hwang, Y.-I., & Park, Y. (2010) · American Journal of Orthodontics and Dentofacial Orthopedics · doi:10.1016/j.ajodo.2009.10.025 · Cited by 235 · see citing works
Krailassiri, S., Anuwongnukroh, N., & Dechkunakorn, S. (2002) · PubMed · doi:10.1043/0003-3219(2002)072 · Cited by 205 · see citing works
Felippe, N. L. O. D., Silveira, A. C. D., Viana, G., et al. (2008) · American Journal of Orthodontics and Dentofacial Orthopedics · doi:10.1016/j.ajodo.2006.10.034 · Cited by 186 · see citing works
Xu, C. D., Sin, S., McDonough, J. M., et al. (2005) · Journal of Biomechanics · doi:10.1016/j.jbiomech.2005.06.021 · Cited by 174 · see citing works
The effect of rapid maxillary expansion on nasal airway resistance
Hartgerink, D. V., Vig, P. S., Orth, D., & Abbott, D. W. (1987) · American Journal of Orthodontics and Dentofacial Orthopedics · doi:10.1016/0889-5406(87)90258-7 · Cited by 169 · see citing works
Christie, K. F., Boucher, N. S., & Chung, C. (2010) · American Journal of Orthodontics and Dentofacial Orthopedics · doi:10.1016/j.ajodo.2008.11.024 · Cited by 161 · see citing works
Cross, D. (2000) · European Journal of Orthodontics · doi:10.1093/ejo/22.5.519 · Cited by 144 · see citing works
Results of 310 cases of rapid maxillary expansion selected for medical reasons
Gray, L. P. (1975) · The Journal of Laryngology & Otology · doi:10.1017/s0022215100080804 · Cited by 137 · see citing works
Value of Acoustic Rhinometry for Measuring Nasal Valve Area
Çakmak, Ö., Çoşkun, M., Çelik, H., Büyüklü, F., & Özlüoğlu, L. N. (2003) · The Laryngoscope · doi:10.1097/00005537-200302000-00018 · Cited by 135 · see citing works
Iwasaki, T., Hayasaki, H., Takemoto, Y., et al. (2009) · American Journal of Orthodontics and Dentofacial Orthopedics · doi:10.1016/j.ajodo.2009.02.017 · Cited by 135 · see citing works
Self-citationBacker, J. W. D., Vanderveken, O. M., Vos, W. G., Devolder, A., Verhulst, S. L., Verbraecken, J. A., Parizel, P. M., Braem, M. J. A., de Heyning, P. V., & Backer, W. A. D. (2007) · Journal of Biomechanics · doi:10.1016/j.jbiomech.2007.06.022 · Cited by 123 · see citing works
Evaluation of nasal airway resistance during rapid maxillary expansion using acoustic rhinometry
Doruk, C. (2004) · European Journal of Orthodontics · doi:10.1093/ejo/26.4.397 · Cited by 117 · see citing works
Evaluation of the human airway using cone-beam computerized tomography
Tso, H. H., Lee, J. S., Huang, J. C., Maki, K., Hatcher, D. C., & Miller, A. J. (2009) · Oral Surgery Oral Medicine Oral Pathology Oral Radiology and Endodontology · doi:10.1016/j.tripleo.2009.05.026 · Cited by 114 · see citing works
Rapid Maxillary Expansion for the Treatment of Nasal Obstruction in Children Younger Than 12 Years
Monini, S., Malagola, C., Villa, M. P., Tripodi, C., Tarentini, S., Malagnino, I., Marrone, V., Lazzarino, A. I., & Barbara, M. (2009) · Archives of Otolaryngology - Head and Neck Surgery · doi:10.1001/archoto.2008.521 · Cited by 102 · see citing works
Doruk, C., Sökücü, O., Bicakci, A. A., et al. (2007) · European Journal of Orthodontics · doi:10.1093/ejo/cjl069 · Cited by 100 · see citing works
Changes in nasal air flow incident to rapid maxillary expansion
(1967) · American Journal of Orthodontics · doi:10.1016/0002-9416(67)90194-7 · Cited by 96 · see citing works
Nasal Airway Measurements in Children Treated by Rapid Maxillary Expansion
Compadretti, G. C., Tasca, I., & Bonetti, G. A. (2006) · American Journal of Rhinology · doi:10.2500/ajr.2006.20.2881 · Cited by 95 · see citing works
Numerical flow simulation in the post-endoscopic sinus surgery nasal cavity
Xiong, G., Zhan, J.-M., Zuo, K., et al. (2008) · Medical & Biological Engineering & Computing · doi:10.1007/s11517-008-0384-1 · Cited by 94 · see citing works
Haralambidis, A., Demirkaya, A. A., Acar, A., et al. (2009) · American Journal of Orthodontics and Dentofacial Orthopedics · doi:10.1016/j.ajodo.2008.03.020 · Cited by 68 · see citing works
Evaluation of upper airway obstruction in Class II children with fluid-mechanical simulation
Iwasaki, T., Saitoh, I., Takemoto, Y., et al. (2011) · American Journal of Orthodontics and Dentofacial Orthopedics · doi:10.1016/j.ajodo.2010.08.014 · Cited by 68 · see citing works
Self-citationUse of conventional tomography to evaluate changes in the nasal cavity with rapid palatal expansion
Palaisa, J., Ngan, P., Martin, C. A., & Razmus, T. F. (2007) · American Journal of Orthodontics and Dentofacial Orthopedics · doi:10.1016/j.ajodo.2005.10.025 · Cited by 67 · see citing works
Some Medical Aspects of Rapid Maxillary Expansion
Timms, D. J. (1974) · British Journal of Orthodontics · doi:10.1179/bjo.1.4.127 · Cited by 65 · see citing works
Long-term effects of orthodontic therapy on the maxillary dental arch and nasal cavity
Felippe, N. L. O. D., Bhushan, N., Silveira, A. C. D., Viana, G., & Smith, B. E. (2009) · American Journal of Orthodontics and Dentofacial Orthopedics · doi:10.1016/j.ajodo.2009.02.019 · Cited by 60 · see citing works
Orthodontic maxillary expansion and its effect on nocturnal enuresis.
Kurol, J., Modin, H., & Bjerkhoel, A. (1998) · PubMed · doi:10.1043/0003-3219(1998)068 · Cited by 55 · see citing works
The effect of rapid maxillary expansion on nasal airway resistance.
White, B., Woodside, D. G., & Cole, P. (1989) · PubMed · Cited by 50 · see citing works
Principato, J. J., & Wolf, P. H. (1985) · The Laryngoscope · doi:10.1288/00005537-198509000-00009 · Cited by 48 · see citing works
Acoustic rhinometry: an explanation of some common artefacts associated with nasal decongestion
Tomkinson, & Eccles (1998) · Clinical Otolaryngology · doi:10.1046/j.1365-2273.1998.00066.x · Cited by 47 · see citing works
Rapid maxillary expansion in the treatment of nasal obstruction and respiratory disease
Timms, D. J. (1988) · American Journal of Orthodontics and Dentofacial Orthopedics · doi:10.1016/0889-5406(88)90178-3 · Cited by 46 · see citing works
Gamiño, B., & Aguillón, J. (2009) · Fuel · doi:10.1016/j.fuel.2009.06.030 · Cited by 44 · see citing works
The limitations of peak nasal flow measurement
Clarke, R. W., & Jones, A. S. (1994) · Clinical Otolaryngology · doi:10.1111/j.1365-2273.1994.tb01277.x · Cited by 41 · see citing works
Measurement of nasal resistance by rhinomanometry in 892 Japanese elementary school children
Kobayashi, R., Miyazaki, S., Karaki, M., Kobayashi, E., Karaki, R., Akiyama, K., Matsubara, A., & Mori, N. (2011) · Auris Nasus Larynx · doi:10.1016/j.anl.2010.06.002 · Cited by 40 · see citing works
The effect of rapid maxillary expansion on nasal airway resistance
Mosby, E. L. (1990) · Journal of Oral and Maxillofacial Surgery · doi:10.1016/0278-2391(90)90252-w · Cited by 39 · see citing works
Çakmak, Ö., Tarhan, E., Çoşkun, M., et al. (2005) · Annals of Otology Rhinology & Laryngology · doi:10.1177/000348940511401211 · Cited by 36 · see citing works
Re: Correlation between subjective and objective evaluation of the nasal airway
Eccles, R., Doddi, N. M., & Leong, S. (2010) · Clinical Otolaryngology · doi:10.1111/j.1749-4486.2010.02101.x · Cited by 33 · see citing works
Comparative cleansing efficiency of an electric and a manual toothbrush in orthodontic patients.
Womack, W., & Guay, A. H. (1968) · PubMed · doi:10.1043/0003-3219(1968)038 · Cited by 26 · see citing works
Comparison of the effects of RME and fan-type RME on nasal airway by using acoustic rhinometry
Sökücü, O., Doruk, C., & Uysal, Ö. (2010) · The Angle Orthodontist · doi:10.2319/120309-694.1 · Cited by 25 · see citing works
Iwasaki, T., Hayasaki, H., Takemoto, Y., et al. (2009) · American Journal of Orthodontics and Dentofacial Orthopedics · doi:10.1016/j.ajodo.2009.04.010 · Cited by 22 · see citing works
Self-citationJones, A. S., & Lancer, J. M. (1987) · Clinical Otolaryngology · doi:10.1111/j.1365-2273.1987.tb00193.x · Cited by 21 · see citing works
Nasal impairment in prepubertal children
Crouse, U. K., Laine‐Alava, M. T., & Warren, D. W. (2000) · American Journal of Orthodontics and Dentofacial Orthopedics · doi:10.1067/mod.2000.104952 · Cited by 20 · see citing works
Rapid maxillary expansion and impaired nasal respiration.
Lp, G. (1987) · PubMed · Cited by 19 · see citing works
Rapid maxillary expansion and impaired nasal respiration
Jacobson, A. (1988) · American Journal of Orthodontics and Dentofacial Orthopedics · doi:10.1016/0889-5406(88)90179-5 · Cited by 18 · see citing works
Felippe, N. L. O. D., Bhushan, N., Silveira, A. C. D., et al. (2009) · American Journal of Orthodontics and Dentofacial Orthopedics · doi:10.1016/j.ajodo.2009.05.001 · Cited by 8 · see citing works
Flagged first, then by citations
Cited by
Sorted by citations
International Consensus Statement on Obstructive Sleep Apnea
Chang, J. L., Goldberg, A. N., Alt, J. A., Mohammed, A., Ashbrook, L., Auckley, D., Ayappa, I., Bakhtiar, H., Barrera, J. E., Bartley, B. L., et al. (2023) · International Forum of Allergy & Rhinology · doi:10.1002/alr.23079 · Cited by 350 · see citing works
Advances in Technology for Functional Rhinoplasty
Pawar, S. S., Garcia, G. J. M., & Rhee, J. S. (2017) · Facial Plastic Surgery Clinics of North America · doi:10.1016/j.fsc.2016.12.009 · Cited by 14 · see citing works
Aydil, S. K., Kiyan, E., Ersu, R., Kilicoglu, H., Sayar, G., & Capan, E. (2026) · Clinical Oral Investigations · doi:10.1007/s00784-026-06926-4 · Cited by 2 · see citing works
“Several studies have explored the long-term impact of these devices, particularly their ability to sustain mandibular advancement and cephalometric gains in airway dimensions in growing children [12–15].”
- Authors
- Iwasaki, T., Saitoh, I., Takemoto, Y., Inada, E., Kanomi, R., Hayasaki, H., & Yamasaki, Y.
- Affiliations
- Kagoshima University (JP)
- Niigata University (JP)
- Corresponding author
- Iwasaki, Tomonori
- Venue
- American Journal of Orthodontics and Dentofacial Orthopedics
- Publisher
- Elsevier BV
- Published
- 2012-03
- Volume
- 141
- Issue
- 3
- Pages
- 269-278
- ISSN
- 0889-5406 (ISSN-L)
- OpenAlex
- W2123856165
- Cited by
- 90
- References
- 47
- Citations by year
- 2026: 8 · 2025: 5 · 2024: 7 · 2023: 4 · 2022: 7 · 2021: 10 · 2020: 4 · 2019: 8 · 2018: 7 · 2017: 7 · 2016: 3 · 2015: 7 · 2014: 3 · 2013: 6 · 2012: 4
- FWCI
- 6.51
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- American Journal of Orthodontics and Dentofacial Orthopedics (publishedVersion)
- PubMed (publishedVersion)
- Funders
- KAKENHI
- Japan Society for the Promotion of Science (19592360, 22592292)
- Topics
- Health Sciences › Medicine › Surgery › Nasal Surgery and Airway Studies
- Health Sciences › Dentistry › Orthodontics › Orthodontics and Dentofacial Orthopedics
- Life Sciences › Biochemistry, Genetics and Molecular Biology › Genetics › Cleft Lip and Palate Research
- Keywords
- rapid maxillary expansion, nasal airflow, nasal cavity, computational fluid dynamics, nasal pressure, orthodontic treatment, pediatric patients
- MeSH terms
- Inhalation, Child, Dental Arch, Female, Follow-Up Studies, Humans, Image Processing, Computer-Assisted, Longitudinal Studies, Male, Maxilla, Nasal Cavity, Orthodontics, Corrective, Palatal Expansion Technique, Pressure, Pulmonary Ventilation, Nasal Obstruction, Computational Biology, Imaging, Three-Dimensional, Exhalation, Cone-Beam Computed Tomography, Hydrodynamics
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
Are you an author, or do you see a problem with this page? Request a review
