Cited by 181Maternal Mental Health During Pregnancy and PostpartumMaternal and Neonatal HealthcareInfant Development and Preterm Care

Prenatal life events stress: implications for preterm birth and infant birthweight

Zhu, Peng, Tao, Fangbiao, Hao, Jiahu, Sun, Ying, Jiang, Xiaomin·2010·American Journal of Obstetrics and Gynecology

Abstract

Objective The objective of the study was to evaluate the effects of maternal exposure to severe life events during different stage of gestation on preterm birth and infant birthweight.Study design A sample of 1800 women who delivered after 32 weeks' gestation were assessed with questionnaires that measured stressful life events during different stages of pregnancy. Demographic characteristics and birth outcomes were collected through the interviews and medical charts.Results There was an increased risk of preterm birth among women with higher levels of life events stress during the first trimester (adjusted risk ratio, 2.40; 95% confidence interval, 1.13-5.09) and second trimester (adjusted risk ratio, 2.86; 95% confidence interval, 1.26-6.47). Each unit increase of perceived life events stress during first trimester was associated with a 99.09 g decrease in infant birthweight.Conclusion Prenatal severe life events, especially in the first trimester, may play an important role in increasing the risk of preterm birth and low birthweight.

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Crossref · 10.1016/j.ajog.2010.02.023

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  • Women with increased life event stress during the first trimester of pregnancy had 2.40 times the risk of preterm birth compared with women with average or below-average stress.

    “in these studies, women with increased life event stress during the first trimester of pregnancy had 2.40 times the risk of PTB compared with women with average or below-average stress.80”

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References 29 · Cited by 181

Authors
Zhu, P., Tao, F., Hao, J., Sun, Y., & Jiang, X.
Affiliations
Anhui Medical University (CN)
Corresponding author
Tao, Fangbiao
Venue
American Journal of Obstetrics and Gynecology
Publisher
Elsevier BV
Published
2010-07
Volume
203
Issue
1
Pages
34.e1-34.e8
ISSN
0002-9378 (ISSN-L)
OpenAlex
W1982353175
Cited by
181
References
29
Citations by year
2026: 3 · 2025: 7 · 2024: 7 · 2023: 10 · 2022: 13 · 2021: 12 · 2020: 20 · 2019: 11 · 2018: 16 · 2017: 12 · 2016: 14 · 2015: 12 · 2014: 14 · 2013: 12 · 2012: 7
FWCI
9.41
Type
journal article
Language
en
Open access
closed
Locations
  • American Journal of Obstetrics and Gynecology (publishedVersion)
  • PubMed (publishedVersion)
Topics
  • Health Sciences › Medicine › Public Health, Environmental and Occupational Health › Maternal Mental Health During Pregnancy and Postpartum
  • Health Sciences › Health Professions › General Health Professions › Maternal and Neonatal Healthcare
  • Health Sciences › Medicine › Pediatrics, Perinatology and Child Health › Infant Development and Preterm Care
Keywords
prenatal stress, life events, preterm birth, low birth weight, birth weight, first trimester, second trimester, maternal mental health, pregnancy
MeSH terms
Adult, Birth Weight, China, Female, Gestational Age, Humans, Infant, Newborn, Longitudinal Studies, Pregnancy, Pregnancy Complications, Prospective Studies, Surveys and Questionnaires, Socioeconomic Factors, Stress, Psychological, Logistic Models, Premature Birth, Young Adult

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