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Medication use during pregnancy, with particular focus on prescription drugs: 1976-2008
Open accessAbstract
Objective To provide information on overall medication use throughout pregnancy, with particular focus on the first trimester and specific prescription medications. Study Design The Slone Epidemiology Center Birth Defects Study (BDS), 1976 to 2008, and the National Birth Defects Prevention Study (NBDPS), 1997 to 2003, which together interviewed over 30,000 women about their antenatal medication use. Results Over the last three decades, first trimester use of prescription medication increased by over 60%, and use of four or more medications more than tripled. By 2008, approximately 50% of women reported taking at least 1 medication. Use of some specific medications markedly decreased or increased. Prescription medication use increased with maternal age and education, was highest for non-Hispanic whites, and varied by state. Conclusion These data reflect the widespread and growing use of medications by pregnant women and reinforce the need to study their respective fetal risks and safety.
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Cited by
Jarde, A., Morais, M., Kingston, D., Giallo, R., MacQueen, G. M., Giglia, L., Beyene, J., Wang, Y., & McDonald, S. D. (2016) · JAMA Psychiatry · doi:10.1001/jamapsychiatry.2016.0934 · Cited by 616
Pregnancy-Associated Changes in Pharmacokinetics: A Systematic Review
Pariente, G., Leibson, T., Carls, A., Adams-Webber, T., Ito, S., & Koren, G. (2016) · PLOS Medicine · doi:10.1371/journal.pmed.1002160 · Cited by 336
Pregnant women with posttraumatic stress disorder and risk of preterm birth
Yonkers, K. A., Smith, M. V., Forray, A., Epperson, C. N., Costello, D., Lin, H., & Belanger, K. (2014) · JAMA Psychiatry · doi:10.1001/jamapsychiatry.2014.558 · Cited by 331
Rosenfeld, C. S. (2021) · Journal of Neuroscience Research · doi:10.1002/jnr.24603 · Cited by 280
National trends in antidepressant medication treatment among publicly insured pregnant women
Huybrechts, K. F., Palmsten, K., Mogun, H., Kowal, M., Avorn, J., Setoguchi-Iwata, S., & Hernández-Díaz, S. (2013) · General Hospital Psychiatry · doi:10.1016/j.genhosppsych.2012.12.010 · Cited by 161
Metadata
- Authors
- Mitchell, A. A., Gilboa, S. M., Werler, M. M., Kelley, K. E., Louik, C., & Hernández-Díaz, S.
- Venue
- American Journal of Obstetrics and Gynecology
- Publisher
- Elsevier BV
- Published
- 2011-07
- Volume
- 205
- Issue
- 1
- Pages
- 51.e1-51.e8
- ISSN
- 0002-9378 (ISSN-L)
- OpenAlex
- W2024474319
- Cited by
- 813
- References
- 0
- FWCI
- 27.34
- Type
- journal article
- Language
- en
- Open access
- green
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