The DOI matches its Crossref record; 188 of the 188 references it cites were found in a registry or an index.
Vaginal progesterone in women with an asymptomatic sonographic short cervix in the midtrimester decreases preterm delivery and neonatal morbidity: a systematic review and metaanalysis of individual patient data
Open accessAbstract
OBJECTIVE To determine whether the use of vaginal progesterone in asymptomatic women with a sonographic short cervix in the mid-trimester reduces the risk of preterm birth and improves neonatal morbidity and mortality. STUDY DESIGN Individual patient data meta-analysis of randomized controlled trials. RESULTS Five trials of high quality were included with a total of 775 women and 827 infants. Treatment with vaginal progesterone was associated with a significant reduction in the rate of preterm birth <33 weeks (RR 0.58, 95% CI 0.42–0.80), <35 weeks (RR 0.69, 95% CI 0.55–0.88) and <28 weeks (RR 0.50, 95% CI 0.30–0.81), respiratory distress syndrome (RR 0.48, 95% CI 0.30–0.76), composite neonatal morbidity and mortality (RR 0.57, 95% CI 0.40–0.81), birth weight <1500 g (RR 0.55, 95% CI 0.38–0.80), admission to NICU (RR 0.75, 95% CI 0.59–0.94), and requirement for mechanical ventilation (RR 0.66, 95% CI 0.44–0.98). There were no significant differences between the vaginal progesterone and placebo groups in the rate of adverse maternal events or congenital anomalies. CONCLUSION Vaginal progesterone administration to asymptomatic women with a sonographic short cervix reduces the risk of preterm birth and neonatal morbidity and mortality.
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1 retracted
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Epidemiology and causes of preterm birth
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“Vaginal progesterone administration to asymptomatic women with a sonographic short cervix in the midtrimester was associatedwith: (1)asignificant42%reduction in the rate of preterm birth 33 weeks (primary outcome); (2) a significant reduction in the risk of preterm birth 35, 34, 30, and 28 weeks and a trend for reduct…”
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Preterm labor: One syndrome, many causes
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Self-citationISUOG Practice Guidelines: role of ultrasound in twin pregnancy
Khalil, A., Rodgers, M., Baschat, A., Bhide, A., Gratacos, E., Hecher, K., Kilby, M. D., Lewi, L., Nicolaides, K. H., Oepkes, D., et al. (2016) · Ultrasound in Obstetrics & Gynecology · doi:10.1002/uog.15821 · Cited by 645
Self-citationRomero, R., Conde-Agudelo, A., Da Fonseca, E., O’Brien, J. M., Cetingoz, E., Creasy, G. W., Hassan, S. S., & Nicolaides, K. H. (2018) · American Journal of Obstetrics and Gynecology · doi:10.1016/j.ajog.2017.11.576 · Cited by 522
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Metadata
- Authors
- Romero, R., Nicolaides, K., Conde-Agudelo, A., Tabor, A., O'Brien, J. M., Cetingoz, E., Da Fonseca, E., Creasy, G. W., Klein, K., Rode, L., Soma-Pillay, P., Fusey, S., Cam, C., Alfirevic, Z., & Hassan, S. S.
- Venue
- American Journal of Obstetrics and Gynecology
- Publisher
- Elsevier BV
- Published
- 2012-02
- Volume
- 206
- Issue
- 2
- Pages
- 124.e1-124.e19
- ISSN
- 0002-9378 (ISSN-L)
- OpenAlex
- W2144088431
- Cited by
- 580
- References
- 188
- FWCI
- 5.70
- Type
- journal article
- Language
- en
- Open access
- bronze
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- Romero, R., Nicolaides, K., Conde-Agudelo, A., Tabor, A., O'Brien, J. M., Cetingoz, E., Da Fonseca, E., Creasy, G. W., Klein, K., Rode, L., Soma-Pillay, P., Fusey, S., Cam, C., Alfirevic, Z., & Hassan, S. S. (2012). Vaginal progesterone in women with an asymptomatic sonographic short cervix in the midtrimester decreases preterm delivery and neonatal morbidity: a systematic review and metaanalysis of individual patient data. American Journal of Obstetrics and Gynecology. https://doi.org/10.1016/j.ajog.2011.12.003
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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
