Effect of noise stress on male rat fertility, and the protective effect of vitamins C and E on its potential effect
Open accessAbstract
OBJECTIVE: To evaluate the effect of noise on the fertility of male rats, and to assess the effect of vitamins C and E on its potential effect. MATERIALS AND METHODS: Forty adult male rats were randomly divided into five equal groups. Group 1 (control) was not exposed to noise. Groups 2-5 were exposed to noise of 90-130 dB and 300-350 Hz from 19.00 to 07.00 h every day for 50 days; group 2 received vitamin C and group 3 received vitamin E. Group 4 received vitamins C and E concomitantly and group 5 received no vitamins. After 50 days, the serum levels of follicle-stimulating hormone (FSH), luteinising hormone (LH) and testosterone were measured. Each rat was then left for 1 week with three female rats, for mating. Pregnant females were killed humanely after 19 days of pregnancy and evaluated for the presence and number of viable, dead and absorbed fetuses. RESULTS: The mean serum FSH level was statistically significantly different between the control and groups 2 (P < 0.05) and 5 (P < 0.001). The mean serum LH level differed significantly between the control and groups 2 (P = 0.05), 3 (P < 0.05) and 5 (P < 0.001). The mean serum testosterone level was significantly different between the control and group 5 (P < 0.001). Serum FSH, LH and testosterone levels in group 5 were significantly different from all the others (P < 0.001). The pregnancy rates in females mated with groups 1 and 5 were statistically different (P < 0.05). Comparing groups 1-4, there was no difference in the occurrence of abnormal pregnancy (P > 0.05), but group 5 values were significantly different from the others (P < 0.001). CONCLUSION: These data strongly suggest that noise stress has a significant effect on the fertility of male rats.
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Stress induced by noise reduces fertility in male rats and results in killing the offspring.
“Stress (induced by noise) reduces fertility in male rats 31 and results in killing the offspring.32”
From Ecological validity of social interaction tests in rats and mice (2019) · cites this paper as [31]
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- Authors
- Fathollahi, A., Jasemi, M., & Saki, G.
- Affiliations
- Ahvaz Jundishapur University of Medical Sciences (IR)
- Corresponding author
- Fathollahi, Ali
- Venue
- Arab Journal of Urology
- Publisher
- Informa UK Limited
- Published
- 2013-03
- Volume
- 11
- Issue
- 1
- Pages
- 101-105
- ISSN
- 2090-598X (ISSN-L)
- 2090-5998
- PMC
- PMC4461010
- OpenAlex
- W2037929500
- Semantic Scholar
- f2628c4e69f1d882f18d181a2c9317f00a72d11b
- Cited by
- 21
- References
- 18
- Citations by year
- 2026: 1 · 2023: 2 · 2022: 1 · 2021: 2 · 2020: 1 · 2019: 3 · 2018: 3 · 2017: 2 · 2016: 2 · 2015: 3 · 2014: 1
- FWCI
- 4.59
- Type
- journal article
- Language
- en
- Open access
- diamond
- doi.org
- Licence
- Locations
- Arab Journal of Urology (publishedVersion, cc-by-nc-nd)
- Europe PMC (PubMed Central) (publishedVersion, cc-by-nc-nd)
- PubMed Central (publishedVersion, cc-by-nc-nd)
- PubMed (publishedVersion)
- Topics
- Health Sciences › Health Professions › Speech and Hearing › Noise Effects and Management
- Health Sciences › Medicine › Reproductive Medicine › Sperm and Testicular Function
- Health Sciences › Medicine › Public Health, Environmental and Occupational Health › Reproductive Biology and Fertility
- Keywords
- noise stress, male fertility, vitamin C, vitamin E, antioxidants, follicle-stimulating hormone, luteinizing hormone, testosterone, reproductive toxicity, pregnancy rate
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