Genetic Polymorphisms of Alcohol and Aldehyde Dehydrogenases and Risk for Esophageal and Head and Neck Cancers
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Genetic variations in the aldehyde dehydrogenase 2 gene affect the risk relationship between alcohol consumption and oral cavity and oesophageal cancer.
“Specifically, genetic variations in the aldehyde dehydrogenase 2 gene have been shown to affect the risk relationship between alcohol consumption and oral cavity and oesophageal cancer 175, 181, 183.”
From The relationship between different dimensions of alcohol use and the burden of disease—an update (2017) · cites this paper as [183]
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The relationship between different dimensions of alcohol use and the burden of disease—an update
Rehm, J., Gmel, G. E., Gmel, G., Hasan, O. S. M., Imtiaz, S., Popova, S., Probst, C., Roerecke, M., Room, R., Samokhvalov, A. V., et al. (2017) · Addiction · doi:10.1111/add.13757 · Cited by 1,204 · see citing works
A review of human carcinogens–Part E: tobacco, areca nut, alcohol, coal smoke, and salted fish
Secretan, B., Straif, K., Baan, R., Grosse, Y., El Ghissassi, F., Bouvard, V., Benbrahim-Tallaa, L., Guha, N., Freeman, C., Galichet, L., et al. (2009) · The Lancet Oncology · doi:10.1016/s1470-2045(09)70326-2 · Cited by 1,114 · see citing works
Carcinogenicity of alcoholic beverages
Baan, R., Straif, K., Grosse, Y., Secretan, B., El Ghissassi, F., Bouvard, V., Altieri, A., & Cogliano, V. (2007) · The Lancet Oncology · doi:10.1016/s1470-2045(07)70099-2 · Cited by 877 · see citing works
- Authors
- Yokoyama, A., & Omori, T.
- Affiliations
- Kurihama Medical and Addiction Center (JP)
- Kawasaki Municipal Hospital (JP)
- Corresponding author
- Yokoyama, Akira
- ORCID
- Yokoyama, Akira
- Venue
- Alcohol
- Publisher
- Elsevier BV
- Published
- 2005-04
- Volume
- 35
- Issue
- 3
- Pages
- 175-185
- ISSN
- 0741-8329 (ISSN-L)
- OpenAlex
- W1987086947
- Cited by
- 78
- References
- 0
- Citations by year
- 2025: 2 · 2023: 3 · 2022: 1 · 2021: 1 · 2020: 3 · 2019: 1 · 2018: 1 · 2017: 5 · 2016: 1 · 2015: 5 · 2014: 6 · 2013: 4 · 2012: 11
- FWCI
- 3.11
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- Alcohol (publishedVersion)
- PubMed (publishedVersion)
- Topics
- Health Sciences › Medicine › Pathology and Forensic Medicine › Alcohol Consumption and Health Effects
- Health Sciences › Medicine › Surgery › Esophageal Cancer Research and Treatment
- Health Sciences › Medicine › Otorhinolaryngology › Head and Neck Cancer Studies
- Keywords
- alcohol consumption, upper tract urothelial carcinoma, renal pelvis cancer, alcohol dehydrogenase, aldehyde dehydrogenase, genetic polymorphism, esophageal cancer, head and neck cancer, dose-response relationship, smoking, occupational exposure
- MeSH terms
- Acetaldehyde, Alcohol Dehydrogenase, Alcohol Drinking, Ethanol, Aldehyde Dehydrogenase, Animals, Carcinogens, Central Nervous System Depressants, Esophageal Neoplasms, Genotype, Head and Neck Neoplasms, Humans, Japan, Patch Tests, Polymorphism, Genetic, Risk Assessment
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Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
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