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Gibberellin-regulated protein allergy: Clinical features and cross-reactivity

Inomata, Naoko·2020·Allergology International
DOI 10.1016/j.alit.2019.10.007
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CC-BY-NC-ND · From the PDF
Fig. 1 Gibberellin-regulated proteins (GRPs) identi fi ed as allergens and their cross-reactivity. To date, clinical cross-reactivity between at least four fruit-derived GRPs, Pru p 7, Pru m 7, Cit s 7, and Pun g 7, have been proven. In addition, cross-reactivity between Cypmaclein and two fruit-derived GRPs, Pru p 7 and Pun g 7, has been demonstrated. Left right double arrow indicates cross-reactivity.
Fig. 1 Gibberellin-regulated proteins (GRPs) identi fi ed as allergens and their cross-reactivity. To date, clinical cross-reactivity between at least four fruit-derived GRPs, Pru p 7, Pru m 7, Cit s 7, and Pun g 7, have been proven. In addition, cross-reactivity between Cypmaclein and two fruit-derived GRPs, Pru p 7 and Pun g 7, has been demonstrated. Left right double arrow indicates cross-reactivity.CC-BY-NC-ND · From the PDF
Image 3
CC-BY-NC-ND · From the PDF
Fig. 4 The prevalence of Pru p 7-monosensitization in Japanese patients with fruit allergies. Of 100 Japanese patients with fruit allergies, 20 patients had negative ImmunoCAP results for Bet v 1 homologs and pro fi lin. Of these 20 patients, 13 patients had positive speci fi c immunoglobulin E results by enzyme-linked immunoassay and/or skin prick test (SPT) examinations using puri fi ed nPru p 7 as a representative gibberellin-regulated protein (GRP). One patient was ImmunoCAP positive for nPru p 3 as a representative lipid transfer protein (LTP). y GRP-sensitized patients indicate patients with positive results for nPru p 7 in at least one allergic test. z LTP-sensitized patients indicate patients with positive ImmunoCAP results for Pru p 3.
Fig. 4 The prevalence of Pru p 7-monosensitization in Japanese patients with fruit allergies. Of 100 Japanese patients with fruit allergies, 20 patients had negative ImmunoCAP results for Bet v 1 homologs and pro fi lin. Of these 20 patients, 13 patients had positive speci fi c immunoglobulin E results by enzyme-linked immunoassay and/or skin prick test (SPT) examinations using puri fi ed nPru p 7 as a representative gibberellin-regulated protein (GRP). One patient was ImmunoCAP positive for nPru p 3 as a representative lipid transfer protein (LTP). y GRP-sensitized patients indicate patients with positive results for nPru p 7 in at least one allergic test. z LTP-sensitized patients indicate patients with positive ImmunoCAP results for Pru p 3.CC-BY-NC-ND · From the PDF

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Research works printed but not linked: 31

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Metadata

Authors
Inomata, N.
Venue
Allergology International
Publisher
Elsevier BV
Published
2020-01
Volume
69
Issue
1
Pages
11-18
ISSN
1323-8930
DOI
10.1016/j.alit.2019.10.007
Cited by
65
References
0
Language
en
Licence
Funders
Japan Society for the Promotion of Science (26461663)

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