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Cited by 177Diabetes, Cardiovascular Risks, and LipoproteinsCardiovascular Health and Disease PreventionCardiovascular Disease and Adiposity

The DOI matches its Crossref record; 24 of the 25 references it cites were found in a registry or an index.

Prevalence of coronary heart disease and carotid arterial thickening in patients with the metabolic syndrome (The ARIC Study)

McNeill, Ann Marie, Rosamond, Wayne D., Girman, Cynthia J., Heiss, Gerardo, Golden, Sherita Hill, Duncan, Bruce B., East, Honey E., Ballantyne, Christie·2004·The American Journal of Cardiology
DOI 10.1016/j.amjcard.2004.07.107
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Abstract

We determined the prevalence of the metabolic syndrome (MS) with the criteria recommended by the National Cholesterol and Education Program, Adult Treatment Panel III report and estimated the magnitude of cross-sectional associations between the MS, coronary heart disease (CHD), and atherosclerosis in 14,502 black and white middle-age patients in the Atherosclerosis Risk in Communities Study. CHD was ascertained by standardized procedures and subclinical atherosclerosis was determined by measuring carotid intimal medial wall thickness using B-mode ultrasonography. The prevalence of MS was 30%, with substantial variation across race and gender subgroups. Among women but not among men, MS was significantly associated with increasing low-density lipoprotein cholesterol. CHD prevalence was 7.4% among those with the MS compared with 3.6% in comparison subjects (p <0.0001). After adjustment for established risk factors, subjects who had MS were 2 times more likely to have prevalent CHD than were those who did not have the syndrome. Among individuals free of CHD and stroke, after adjustment for age, gender, and race/center, the average intimal-medial wall thickness of carotid arteries was greater among those with versus those without MS (747 vs 704 mum, p <0.0001). Thus, MS was significantly associated with the presence of CHD and carotid intimal medial wall thickness. Identification of patients who have MS may provide opportunities to initiate CHD prevention strategies.

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Crossref · 10.1016/j.amjcard.2004.07.107

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Metadata

Authors
McNeill, A. M., Rosamond, W. D., Girman, C. J., Heiss, G., Golden, S. H., Duncan, B. B., East, H. E., & Ballantyne, C.
Affiliations
  • University of North Carolina at Chapel Hill (US)
  • Johns Hopkins University (US)
  • Universidade Federal do Rio Grande do Sul (BR)
  • University of Mississippi Medical Center (US)
  • Baylor College of Medicine (US)
Corresponding author
Rosamond, Wayne D.
ORCID
Venue
The American Journal of Cardiology
Publisher
Elsevier BV
Published
2004-11
Volume
94
Issue
10
Pages
1249-1254
ISSN
0002-9149 (ISSN-L)
DOI
10.1016/j.amjcard.2004.07.107
OpenAlex
W2084016774
Cited by
177
References
25
Citations by year
2024: 2 · 2023: 1 · 2021: 2 · 2020: 2 · 2019: 2 · 2018: 4 · 2017: 4 · 2016: 8 · 2015: 4 · 2014: 6 · 2013: 6 · 2012: 12
FWCI
13.69
Type
journal article
Language
en
Open access
closed
Licence
www.elsevier.com/tdm/userlicense/1.0/ (tdm)
Locations
  • The American Journal of Cardiology (publishedVersion)
  • PubMed (publishedVersion)
Funders
  • National Institutes of Health (n01hc55021-47-0-1, n01hc55020-39-0-0, n01hc55016-37-0-0, n01hc055022-024, n01hc55019-35-0-1, n01hc55018-38-0-1, n01hc55015-48-0-1)
  • National Heart, Lung, and Blood Institute (N01-HC55022, N01-HC-55018, N01 HC 55020, N01 HC 55019, ­N01-HC55016, N01‐HC‐55015, N01-HC55021, T32HL007055, 5T32-HL07055)
Topics
  • Health Sciences › Medicine › Endocrinology, Diabetes and Metabolism › Diabetes, Cardiovascular Risks, and Lipoproteins
  • Health Sciences › Medicine › Cardiology and Cardiovascular Medicine › Cardiovascular Health and Disease Prevention
  • Health Sciences › Medicine › Cardiology and Cardiovascular Medicine › Cardiovascular Disease and Adiposity
Keywords
metabolic syndrome, coronary artery disease, carotid intima-media thickness, subclinical atherosclerosis, prevalence, racial differences, sex differences, LDL cholesterol, cardiovascular risk factors, Atherosclerosis Risk in Communities Study
MeSH terms
Carotid Artery Diseases, Coronary Disease, Cross-Sectional Studies, Female, Humans, Male, Middle Aged, Risk Factors, Ultrasonography, Prevalence, Tunica Intima, Tunica Media, Metabolic Syndrome

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