CoChat
Sign Up
Cited by 68Cardiovascular Effects of ExerciseCardiac electrophysiology and arrhythmiasCardiac Arrhythmias and Treatments

The DOI matches its Crossref record; 28 of the 28 references it cites were found in a registry or an index.

Patterns of Ventricular Tachyarrhythmias Associated With Training, Deconditioning and Retraining in Elite Athletes Without Cardiovascular Abnormalities

Biffi, Alessandro, Maron, Barry J., Culasso, Franco, Verdile, Luisa, Fernando, Fredrick, Di Giacinto, Barbara, Di Paolo, Fernando M., Spataro, Antonio, Delise, Pietro, Pelliccia, Antonio·2011·The American Journal of Cardiology
DOI 10.1016/j.amjcard.2010.10.049
Open this paper in CoChat — free account

Abstract

Ventricular tachyarrhythmias commonly occur in trained athletes during ambulatory Holter electrocardiography and are usually associated with a benign course. Such arrhythmias have been demonstrated to be sensitive to short periods of athletic deconditioning; however, their response to retraining is not known. Twenty-four hour Holter electrocardiographic monitoring was performed at peak training and after 3 to 6 months of deconditioning and was repeated in the present study after 2, 6, and 12 months of retraining in 37 athletes with frequent and complex ventricular tachyarrhythmias and without cardiovascular abnormalities. These subjects showed partial (101 to 500 ventricular premature complexes [VPCs]/24 hours) or marked (<100 VPCs) reversibility of arrhythmias after deconditioning. Retraining initially resulted in a significant increase in arrhythmia frequency compared with deconditioning (from 280 ± 475 to 1,542 ± 2,186 VPCs; p = 0.005), couplets (0.14 ± 0.42 to 4.4 ± 8.2; p = 0.005), and nonsustained ventricular tachycardia (from 0 to 0.8 ± 1.8; p = 0.02). Subsequently, a progressive reduction was seen in the frequency of all ventricular arrhythmias during the 1 year of training to well below that at the peak training levels (VPCs 917 ± 1,630, couplets 1.8 ± 4.2, and nonsustained ventricular tachycardia 0.4 ± 1.2). Such annual arrhythmia reduction was significantly greater statistically in those athletes with marked reversibility after deconditioning than in the athletes with partial reversibility (69 ± 139 vs 1,496 ± 1,917 VPCs/24 hours, respectively; p = 0.007). No cardiac events or symptoms occurred during 1 year of follow-up. In conclusion, in elite athletes without cardiovascular disease, a resumption in intense training after deconditioning was associated with variable, but prolonged, suppression of ventricular ectopy. The absence of adverse clinical events or symptoms associated with the resumption of training supports the continued eligibility in competitive sports for such athletes and is also consistent with the benign nature of physiologic athlete's heart syndrome.

Overview

Integrity signals

Registry

Crossref · 10.1016/j.amjcard.2010.10.049

Cites

28 of 28 references verified0 citation errors · 0 not checkable

Statistics

Recomputing p-values needs the paper’s full text.

Verification

Claims the paper makes

This paper’s full text isn’t openly available, so its claims and self-check weren’t run. The registry and citation checks still apply.

Claims other papers make about this one

Each is checked against this paper’s own text: does it say what the citing paper says it does?

Citations

Cites

Flagged first, then by citations

Research works printed but not linked: 1

  1. 2010, Cardiovascular guidelines for eligibility in competitive sports (COCIS– 4th edition), Med Sport, 63, 5

Cited by

Sorted by citations

Related

Metadata

Authors
Biffi, A., Maron, B. J., Culasso, F., Verdile, L., Fernando, F., Di Giacinto, B., Di Paolo, F. M., Spataro, A., Delise, P., & Pelliccia, A.
Affiliations
  • National Research Council (IT)
  • Minneapolis Heart Institute Foundation (US)
  • Sapienza University of Rome (IT)
  • Azienda Ospedaliera Sant'Andrea (IT)
Corresponding author
Biffi, Alessandro
ORCID
Venue
The American Journal of Cardiology
Publisher
Elsevier BV
Published
2011-03
Volume
107
Issue
5
Pages
697-703
ISSN
0002-9149 (ISSN-L)
DOI
10.1016/j.amjcard.2010.10.049
OpenAlex
W1998452040
Cited by
68
References
28
Citations by year
2026: 1 · 2025: 2 · 2024: 2 · 2023: 6 · 2022: 3 · 2021: 4 · 2020: 3 · 2019: 4 · 2018: 3 · 2017: 5 · 2016: 5 · 2015: 5 · 2014: 7 · 2013: 11 · 2012: 5
FWCI
5.49
Type
journal article
Language
en
Open access
closed
Licence
www.elsevier.com/tdm/userlicense/1.0/ (tdm)
Locations
  • The American Journal of Cardiology (publishedVersion)
  • PubMed (publishedVersion)
Topics
  • Health Sciences › Medicine › Cardiology and Cardiovascular Medicine › Cardiovascular Effects of Exercise
  • Health Sciences › Medicine › Cardiology and Cardiovascular Medicine › Cardiac electrophysiology and arrhythmias
  • Health Sciences › Medicine › Cardiology and Cardiovascular Medicine › Cardiac Arrhythmias and Treatments
Keywords
ventricular tachyarrhythmia, athlete's heart, retraining, premature ventricular contractions, non-sustained ventricular tachycardia, ventricular ectopy, elite athletes, Holter monitoring, arrhythmia suppression, athlete eligibility, cardiovascular anomalies, autonomic nervous system, sympathetic nervous system, vagal tone
MeSH terms
Adolescent, Adult, Female, Follow-Up Studies, Heart Rate, Humans, Italy, Male, Electrocardiography, Ambulatory, Incidence, Tachycardia, Ventricular, Cardiovascular Abnormalities, Disease Progression, Cardiovascular Deconditioning, Young Adult, Athletes

About these checks

Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.

Statistics and arithmetic are recomputed, not judged.

Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.

What counts as a claim ›How we measure confidence ›How we check this ›

Are you an author, or do you see a problem with this page? Request a review