Cited by 785Pain Mechanisms and TreatmentsPain Management and TreatmentPain Management and Opioid Use

The DOI matches its Crossref record; 36 of the 36 references it cites were found in a registry or an index.

Treatment of neuropathic pain: an overview of recent guidelines.

O'Connor, Alec B., Dworkin, Robert H.·2009·The American Journal of Medicine

DOI 10.1016/j.amjmed.2009.04.007

Open this paper in CoChat — free account

Abstract

A number of different treatments for neuropathic pain have been studied, but the literature is sizable, rapidly evolving, and lacks important information about practical aspects of patient management. Under the auspices of the International Association for the Study of Pain (IASP) Neuropathic Pain Special Interest Group (NeuPSIG), a consensus process was used to develop evidence-based guidelines for the pharmacologic management of neuropathic pain that take into account clinical efficacy, adverse effects, impact on health-related quality of life, convenience, and costs. On the basis of randomized clinical trials, medications recommended as first-line treatments for neuropathic pain included certain antidepressants (i.e., tricyclic antidepressants and dual reuptake inhibitors of both serotonin and norepinephrine), calcium channel alpha(2)-delta ligands (i.e., gabapentin and pregabalin), and topical lidocaine. Opioid analgesics and tramadol were recommended as second-line treatments that can be considered for first-line use in selected clinical circumstances. Other medications that generally would be used as third-line treatments include certain other antidepressant and antiepileptic medications, topical capsaicin, mexiletine, and N-methyl-d-aspartate receptor antagonists. Two other national and international associations recently published pharmacologic treatment guidelines for neuropathic pain, which are summarized and contrasted with the NeuPSIG recommendations. Recent guidelines for the use of neurostimulation for the treatment of neuropathic pain also are summarized. For all treatments for neuropathic pain, long-term studies, head-to-head comparisons, and studies of treatment combinations are a priority for future research.

Integrity signals

Registry

Crossref · 10.1016/j.amjmed.2009.04.007

Cites

36 of 36 references verified0 citation errors · 0 not checkable

Statistics

Recomputing p-values needs the paper’s full text.

Claims the paper makes

This paper’s full text isn’t openly available, so its claims and self-check weren’t run. The registry and citation checks still apply.

Claims other papers make about this one

Each is checked against this paper’s own text: does it say what the citing paper says it does?

Untitled work
Treede (2008) · doi:10.1212/01.wnl.0000282763.29778.59 · Cited by 2,746
Pharmacologic management of neuropathic pain: Evidence-based recommendations
Dworkin, R. H., O’Connor, A. B., Backonja, M., Farrar, J. T., Finnerup, N. B., Jensen, T. S., Kalso, E. A., Loeser, J. D., Miaskowski, C., Nurmikko, T. J., et al. (2007) · Pain · doi:10.1016/j.pain.2007.08.033 · Cited by 2,126
Self-citation
Algorithm for neuropathic pain treatment: An evidence based proposal
Finnerup, N. B., Otto, M., McQuay, H. J., Jensen, T. S., & Sindrup, S. H. (2005) · Pain · doi:10.1016/j.pain.2005.08.013 · Cited by 1,337
Morphine, Gabapentin, or Their Combination for Neuropathic Pain
Gilron, I., Bailey, J. M., Tu, D., Holden, R. R., Weaver, D. F., & Houlden, R. L. (2005) · New England Journal of Medicine · doi:10.1056/nejmoa042580 · Cited by 1,080
EFNS guidelines on pharmacological treatment of neuropathic pain
Attal, N., Cruccu, G., Haanpää, M. L., Hansson, P. T., Jensen, T. S., Nurmikko, T. J., Sampaio, C., Sindrup, S. H., & Wiffen, P. J. (2006) · European Journal of Neurology · doi:10.1111/j.1468-1331.2006.01511.x · Cited by 877
EFNS guidelines on neurostimulation therapy for neuropathic pain
Cruccu, G., Aziz, T. Z., Garcı́a-Larrea, L., Hansson, P. T., Jensen, T. S., Lefaucheur, J. P., Simpson, B. A., & Taylor, R. S. (2007) · European Journal of Neurology · doi:10.1111/j.1468-1331.2007.01916.x · Cited by 691
Opioids versus antidepressants in postherpetic neuralgia
Raja, S. N., Haythornthwaite, J. A., Pappagallo, M., Clark, M. R., Travison, T. G., Sabeen, S., Royall, R. M., & Max, M. B. (2002) · Neurology · doi:10.1212/wnl.59.7.1015 · Cited by 593
The impact of neuropathic pain on health-related quality of life
Jensen, M. P., Chodroff, M. J., & Dworkin, R. H. (2007) · Neurology · doi:10.1212/01.wnl.0000259085.61898.9e · Cited by 575
Self-citation
Pharmacological Management of Chronic Neuropathic Pain – Consensus Statement and Guidelines from the Canadian Pain Society
Moulin, D., Clark, A., Gilron, I., Ware, M. A., Watson, C., Sessle, B. J., Coderre, T. J., Morley-Forster, P. K., Stinson, J., Boulanger, A., et al. (2007) · Pain Research and Management · doi:10.1155/2007/730785 · Cited by 552
Venlafaxine extended release in the treatment of painful diabetic neuropathy: a double-blind, placebo-controlled study
Rowbotham, M. C., Goli, V., Kunz, N. R., & Lei, D. (2004) · Pain · doi:10.1016/j.pain.2004.05.010 · Cited by 520

Show all 36 references

Sorted by citations

Items 201–300 of 785

Levetiracetam for neuropathic pain in adults
Wiffen, P. J., Derry, S., Moore, R. A., & Lunn, M. P. (2014) · Cochrane Database of Systematic Reviews · doi:10.1002/14651858.cd010943.pub2 · Cited by 39
Diagnostic Accuracy of the Slump Test for Identifying Neuropathic Pain in the Lower Limb
Urban, L. M., & Macneil, B. J. (2015) · Journal of Orthopaedic and Sports Physical Therapy · doi:10.2519/jospt.2015.5414 · Cited by 38
N‐methyl‐ d ‐aspartate receptor‐mediated modulations of the anti‐allodynic effects of 5‐HT1B/1D receptor stimulation in a rat model of trigeminal neuropathic pain
Kayser, V., Latrémolière, A., Hamon, M., & Bourgoin, S. (2010) · European Journal of Pain · doi:10.1016/j.ejpain.2010.09.012 · Cited by 38
The Lipid Receptor G2A (GPR132) Mediates Macrophage Migration in Nerve Injury-Induced Neuropathic Pain
Osthues, T., Zimmer, B., Rimola, V., Klann, K., Schilling, K., Mathoor, P., Angioni, C., Weigert, A., Geißlinger, G., Münch, C., et al. (2020) · Cells · doi:10.3390/cells9071740 · Cited by 40
Patient-reported Outcomes in Subjects with Neuropathic Pain Receiving Pregabalin: Evidence from Medical Practice in Primary Care Settings
Navarro, A. M., Saldaña, M. T., Pérez, C., Torrades, S., & Rejas, J. (2010) · Pain Medicine · doi:10.1111/j.1526-4637.2010.00824.x · Cited by 37
Nontricyclic antidepressant analgesics and pain: Are serotonin norepinephrine reuptake inhibitors (SNRIs) any better?
Watson, P. N. C., Gilron, I., Sawynok, J., & Lynch, M. E. (2011) · Pain · doi:10.1016/j.pain.2011.05.032 · Cited by 37
Post-stroke pain hypersensitivity induced by experimental thalamic hemorrhage in rats is region-specific and demonstrates limited efficacy of gabapentin
Yang, F., Han, F., Lü, Y.-F., Wang, X., Yang, Y. L., Yang, F., Yu, Y., Sun, W., Wang, J., Costigan, M., et al. (2014) · Neuroscience Bulletin · doi:10.1007/s12264-014-1477-5 · Cited by 37
Spinal SIRPα1-SHP2 interaction regulates spinal nerve ligation-induced neuropathic pain via PSD-95-dependent NR2B activation in rats
Peng, H., Chen, G.-D., Lai, C., Hsieh, M.-C., & Lin, T. B. (2012) · Pain · doi:10.1016/j.pain.2012.02.006 · Cited by 37
Gabapentin reduces allodynia and hyperalgesia in painful diabetic neuropathy rats by decreasing expression level of Nav1.7 and p-ERK1/2 in DRG neurons
Zhang, J.-L., Yang, J.-P., Zhang, J., Li, R.-Q., Wang, J., Jan, J.-J., & Zhuang, Q. (2012) · Brain Research · doi:10.1016/j.brainres.2012.11.032 · Cited by 37
Buprenorphine for neuropathic pain in adults
Wiffen, P. J., Derry, S., Moore, A., Stannard, C., Aldington, D. J., Cole, P., & Knaggs, R. (2015) · Cochrane Database of Systematic Reviews · doi:10.1002/14651858.cd011603.pub2 · Cited by 37
Association of Guanosine Triphosphate Cyclohydrolase 1 Gene Polymorphisms with Fibromyalgia Syndrome in a Korean Population
Kim, S.-K., KIM, S.-H., Nah, S., Lee, J. H., Hong, S., Kim, H., Lee, H., Kim, H., Joung, C., Bae, J., et al. (2013) · The Journal of Rheumatology · doi:10.3899/jrheum.120929 · Cited by 37
Long Term Treatment with Enzyme Replacement Therapy in Patients with Fabry Disease
Oder, D., Nordbeck, P., & Wanner, C. (2016) · The Nephron journals/Nephron journals · doi:10.1159/000448968 · Cited by 37
Nonopioid Medications for Pain
Tauben, D. J. (2015) · Physical Medicine and Rehabilitation Clinics of North America · doi:10.1016/j.pmr.2015.01.005 · Cited by 37
Red Pepper
Singletary, K. W. (2011) · Nutrition Today · doi:10.1097/nt.0b013e3182076ff2 · Cited by 37
Desipramine for neuropathic pain in adults
Hearn, L., Moore, R. A., Derry, S., Wiffen, P. J., & Phillips, T. (2014) · Cochrane Database of Systematic Reviews · doi:10.1002/14651858.cd011003 · Cited by 37
Patient demographics and health plan paid costs in chronic inflammatory demyelinating polyneuropathy
Guptill, J. T., Bromberg, M. B., Zhu, L., Sharma, B. K., Thompson, A. R., Krueger, A., & Sanders, D. B. (2013) · Muscle & Nerve · doi:10.1002/mus.24109 · Cited by 36
Antihypersensitivity Effects of Tramadol Hydrochloride in a Rat Model of Postoperative Pain
Kimura, M., Obata, H., & Saito, S. (2012) · Anesthesia & Analgesia · doi:10.1213/ane.0b013e31825683c3 · Cited by 36
Managing Pain in the Elderly Population: Pearls and Pitfalls
Chai, E. J., & Horton, J. R. (2010) · Current Pain and Headache Reports · doi:10.1007/s11916-010-0148-0 · Cited by 36
Gabapentin for once-daily treatment of post-herpetic neuralgia: a review
Moeller‐Bertram, T., Beal, Schilling, & Wallace (2012) · Clinical Interventions in Aging · doi:10.2147/cia.s23783 · Cited by 35
Increasing risk of cannabis use disorder among U.S. veterans with chronic pain: 2005-2019
Mannes, Z. L., Malte, C. A., Olfson, M., Wall, M. M., Keyes, K. M., Martins, S. S., Cerdá, M., Gradus, J. L., Saxon, A. J., Keyhani, S., et al. (2023) · Pain · doi:10.1097/j.pain.0000000000002920 · Cited by 35
Effects of treatment with St. John's Wort on blood glucose levels and pain perceptions of streptozotocin-diabetic rats
Can, Ö. D., Öztürk, Y., Öztürk, N., Sagratini, G., Ricciutelli, M., Vittori, S., & Maggi, F. (2011) · Fitoterapia · doi:10.1016/j.fitote.2011.01.008 · Cited by 35
Use of Natural Compounds in the Management of Diabetic Peripheral Neuropathy
Galuppo, M., Giacoppo, S., Bramanti, P., & Mazzon, E. (2014) · Molecules · doi:10.3390/molecules19032877 · Cited by 35
The role of keratinocyte-derived chemokine (KC) on hyperalgesia caused by peripheral nerve injury in mice
Manjavachi, M. N., da Costa, R., Quintão, N. L. M., & Calixto, J. Β. (2013) · Neuropharmacology · doi:10.1016/j.neuropharm.2013.10.026 · Cited by 35
Comparative Efficacy of Oral Pharmaceuticals for the Treatment of Chronic Peripheral Neuropathic Pain: Meta-Analysis and Indirect Treatment Comparisons
Ney, J. P., Devine, E. B., Watanabe, J. H., & Sullivan, S. D. (2013) · Pain Medicine · doi:10.1111/pme.12091 · Cited by 35
Pharmacologic Therapies in Musculoskeletal Conditions
Loveless, M. S., & Fry, A. L. (2016) · Medical Clinics of North America · doi:10.1016/j.mcna.2016.03.015 · Cited by 35
Mental disorders, participation, and trajectories in the Danish colorectal cancer screening programme: a population-based cohort study
Thomsen, M. K., Jørgensen, M. D., Pedersen, L. H., Erichsen, R., Sørensen, H. T., & Mikkelsen, E. M. (2023) · The Lancet Psychiatry · doi:10.1016/s2215-0366(23)00179-7 · Cited by 34
Updated Neurophysiology of Itch
Ikoma, A. (2013) · Biological and Pharmaceutical Bulletin · doi:10.1248/bpb.b13-00435 · Cited by 33
Effectiveness of Duloxetine Compared With Pregabalin and Gabapentin in Diabetic Peripheral Neuropathic Pain
Happich, M., Schneider, E. M., Boess, F., Wilhelm, S., Schacht, A., Birklein, F., & Ziegler, D. (2013) · Clinical Journal of Pain · doi:10.1097/ajp.0000000000000057 · Cited by 34
Pilot study of duloxetine for cancer patients with neuropathic pain non-responsive to pregabalin.
Matsuoka, H., Makimura, C., Koyama, A., Otsuka, M., Okamoto, W., Fujisaka, Y., Kaneda, H., Tsurutani, J., & Nakagawa, K. (2012) · PubMed · Cited by 34
Tolerability of NGX-4010, a capsaicin 8% dermal patch, following pretreatment with lidocaine 2.5%/prilocaine 2.5% cream in patients with post-herpetic neuralgia
Webster, L. R., Nunez, M., Tark, M. D., Dunteman, E. D., Lu, B., Tobias, J. K., & Vanhove, G. F. (2011) · BMC Anesthesiology · doi:10.1186/1471-2253-11-25 · Cited by 34
Intravenous lidocaine in the management of chronic peripheral neuropathic pain: a randomized-controlled trial
Moulin, D. E., Morley-Forster, P., Pirani, Z., Rohfritsch, C., & Stitt, L. (2019) · Canadian Journal of Anesthesia/Journal canadien d anesthésie · doi:10.1007/s12630-019-01395-8 · Cited by 34
Meta-Analysis of the Effect of Exercise on Neuropathic Pain Induced by Peripheral Nerve Injury in Rat Models
Guo, J., Chen, B., Wang, Y., Zhu, Y., Song, G., Yang, Z., Zheng, Y.-L., Wang, X., & Chen, P. (2019) · Frontiers in Neurology · doi:10.3389/fneur.2019.00636 · Cited by 34
Anxiolytic effects of the novel α2δ ligand mirogabalin in a rat model of chronic constriction injury, an experimental model of neuropathic pain
Murasawa, H., Kobayashi, H., Saeki, K., & Kitano, Y. (2019) · Psychopharmacology · doi:10.1007/s00213-019-05356-3 · Cited by 34
Effects of rosmarinic acid on an experimental model of painful diabetic neuropathy in rats
Hasanein, P., & Zaheri, L. M. (2014) · Pharmaceutical Biology · doi:10.3109/13880209.2014.894090 · Cited by 34
High Energy Diets-Induced Metabolic and Prediabetic Painful Polyneuropathy in Rats
Xie, F., Han, F., Hou, J., Jiao, K., Costigan, M., & Chen, J. (2013) · PLoS ONE · doi:10.1371/journal.pone.0057427 · Cited by 35
K+Channel Modulatory Subunits KChIP and DPP Participate in Kv4-Mediated Mechanical Pain Control
Kuo, Y.-L., Cheng, J., Hou, W., Chang, Y., Du, P.-H., Jian, J.-J., Rau, R.-H., Yang, J.-H., Lien, C., & Tsaur, M.-L. (2017) · Journal of Neuroscience · doi:10.1523/jneurosci.1619-16.2017 · Cited by 34
Extracellular signal-regulated protein kinase activation in spinal cord contributes to pain hypersensitivity in a mouse model of type 2 diabetes
Xu, X., Chen, H., Ling, B., Xu, L., Cao, H., & Zhang, Y. (2013) · Neuroscience Bulletin · doi:10.1007/s12264-013-1387-y · Cited by 33
Effects of Chronic Administration of Amitriptyline, Gabapentin and Minocycline on Spinal Brain-Derived Neurotrophic Factor Expression and Neuropathic Pain Behavior in a Rat Chronic Constriction Injury Model
Vanelderen, P., Rouwette, T., Kozicz, T., Heylen, R. J., Zundert, J. H. M. V., Roubos, E. W., & Vissers, K. C. P. (2013) · Regional Anesthesia & Pain Medicine · doi:10.1097/aap.0b013e31827d611b · Cited by 33
Evaluation of the analgesic effects of ammoxetine, a novel potent serotonin and norepinephrine reuptake inhibitor
Zhang, T., Xue, R., Zhu, L., Li, J., Fan, Q., Zhong, B., Li, Y., Ye, C., & Zhang, Y. (2016) · Acta Pharmacologica Sinica · doi:10.1038/aps.2016.45 · Cited by 34
Triptolide prevents and attenuates neuropathic pain via inhibiting central immune response.
Wang, W., Mei, X., Chen, L., Tang, J., Li, J.-L., Wu, S., Xu, L., & Li, Y. Q. (2012) · PubMed · Cited by 33
Cryptogenic Sensory Polyneuropathy
Pasnoor, M., Dimachkie, M. M., & Barohn, R. J. (2013) · Neurologic Clinics · doi:10.1016/j.ncl.2013.01.008 · Cited by 33
Treatment of painful diabetic peripheral neuropathy
Rosenberg, C. J., & Watson, J. C. (2015) · Prosthetics and Orthotics International · doi:10.1177/0309364614542266 · Cited by 33
Pharmacological Management of Persistent Pain in Older Persons
Reisner, L. A. (2011) · Journal of Pain · doi:10.1016/j.jpain.2011.01.001 · Cited by 33
New developments in the treatment algorithm for peripheral neuropathic pain.
de Leon-Casasola, O. (2011) · Pain Medicine · doi:10.1111/j.1526-4637.2011.01160.x · Cited by 32
Prolonged-release oxycodone/naloxone in the treatment of neuropathic pain – results from a large observational study
Hermanns, K., JUNKER, U., & Nolte, T. (2012) · Expert Opinion on Pharmacotherapy · doi:10.1517/14656566.2012.648615 · Cited by 32
Acid-Sensing Ion Channels and Pain
Gu, Q., & Lee, L. (2010) · Pharmaceuticals · doi:10.3390/ph3051411 · Cited by 33
From evidence based medicine to mechanism based medicine. Reviewing the role of pharmacogenetics
KNMP working group Pharmacogenetics, Wilffert, B., Swen, J. J., Mulder, H., Touw, D. J., der Zee, A. H. M., & Deneer, V. H. M. (2010) · International Journal of Clinical Pharmacy · doi:10.1007/s11096-010-9446-1 · Cited by 32
Sinomenine facilitates the efficacy of gabapentin or ligustrazine hydrochloride in animal models of neuropathic pain
Gao, T., Shi, T., Wiesenfeld‐Hallin, Z., Li, T., Jiang, J., & Xu, X. (2019) · European Journal of Pharmacology · doi:10.1016/j.ejphar.2019.03.061 · Cited by 32
Neurologic Evaluation and Management of Perioperative Nerve Injury
Watson, J. C., & Huntoon, M. A. (2015) · Regional Anesthesia & Pain Medicine · doi:10.1097/aap.0000000000000185 · Cited by 31
The role of magnesium in pain
Na, H., Ryu, J. H., & Do, S. H. (2011) · University of Adelaide Press eBooks · doi:10.1017/upo9780987073051.012 · Cited by 30
Inhibition of MicroRNA-15a/16 Expression Alleviates Neuropathic Pain Development through Upregulation of G Protein-Coupled Receptor Kinase 2
Li, T., Wan, Y., Sun, L., Tao, S., Chen, P., Liu, C., Wang, K., Zhou, C., & Zhao, G. (2019) · Biomolecules & Therapeutics · doi:10.4062/biomolther.2018.073 · Cited by 30
MicroRNA‐144 relieves chronic constriction injury‐induced neuropathic pain via targeting RASA1
Zhang, X., Guo, H., Xie, A., Liao, O., Ju, F., & Zhou, Y. (2019) · Biotechnology and Applied Biochemistry · doi:10.1002/bab.1854 · Cited by 31
Bibliometric Analysis of Exercise and Neuropathic Pain Research
Chen, Y., & Wang, X. (2020) · Journal of Pain Research · doi:10.2147/jpr.s258696 · Cited by 30
Injury to the lateral cutaneous nerve of forearm after venous cannulation: A case report and literature review
Stevens, R. J. G., Mahadevan, V., & Moss, A. L. H. (2011) · Clinical Anatomy · doi:10.1002/ca.21285 · Cited by 30
Duloxetine in the treatment of chronic pain due to fibromyalgia and diabetic neuropathy
Wright (2010) · Journal of Pain Research · doi:10.2147/jpr.s12866 · Cited by 29
Symptom-Based Treatment of Neuropathic Pain in Spinal Cord-Injured Patients
Min, K., Oh, Y., Lee, S., & Ryu, J. S. (2015) · American Journal of Physical Medicine & Rehabilitation · doi:10.1097/phm.0000000000000382 · Cited by 30
Erratum zu: Opioide bei chronischen nicht-tumorbedingten Schmerzen – sind sie Nichtopioidanalgetika überlegen?: Systematische Übersicht und Metaanalyse der Wirksamkeit, Verträglichkeit und Sicherheit in randomisierten Direktvergleichen von Opioiden und Nichtopioidanalgetika über mindestens 4 Wochen
Welsch, P., Sommer, C., Schiltenwolf, M., & Häuser, W. (2015) · Der Schmerz · Cited by 30
Morphine Self-Administration following Spinal Cord Injury
Woller, S. A., Malik, J. S., Aceves, M., & Hook, M. A. (2014) · Journal of Neurotrauma · doi:10.1089/neu.2013.3293 · Cited by 29
A review on the efficacy and safety of gabapentin in the treatment of chronic cough
Ryan, N. (2014) · Expert Opinion on Pharmacotherapy · doi:10.1517/14656566.2015.981524 · Cited by 29
Management of Chronic Pain in Nursing Homes: Navigating Challenges to Improve Person-Centered Care
Sheikh, F., Brandt, N., Vinh, D., & Elon, R. D. (2021) · Journal of the American Medical Directors Association · doi:10.1016/j.jamda.2020.12.029 · Cited by 29
Differential Effects of Peripheral versus Central Coadministration of QX-314 and Capsaicin on Neuropathic Pain in Rats
Shen, J., Fox, L. E., & Cheng, J. (2012) · Anesthesiology · doi:10.1097/aln.0b013e318260de41 · Cited by 29
Relief of Hypersensitivity after Nerve Injury from Systemic Donepezil Involves Spinal Cholinergic and γ-Aminobutyric Acid Mechanisms
Kimura, M., Hayashida, K., Eisenach, J. C., Saito, S., & Obata, H. (2012) · Anesthesiology · doi:10.1097/aln.0b013e318277a81c · Cited by 29
Case Report of Subanesthetic Intravenous Ketamine Infusion for the Treatment of Neuropathic Pain and Depression with Suicidal Features in a Pediatric Patient
Weber, G. M., Yao, J., Binns, S., & Namkoong, S. (2018) · Case Reports in Anesthesiology · doi:10.1155/2018/9375910 · Cited by 29
Analgesic effects of mirogabalin, a novel ligand for α2δ subunit of voltage-gated calcium channels, in experimental animal models of fibromyalgia
Saeki, K., Yasuda, S.-I., Kato, M., Kano, M., Domon, Y., Arakawa, N., & Kitano, Y. (2019) · Naunyn-Schmiedeberg s Archives of Pharmacology · doi:10.1007/s00210-019-01628-z · Cited by 29
Tolerability of NGX-4010, a capsaicin 8% patch, in conjunction with three topical anesthetic formulations for the treatment of neuropathic pain
Webster, L. R., Peppin, J. F., Murphy, Tobias, J. K., & Vanhove (2012) · Journal of Pain Research · doi:10.2147/jpr.s25272 · Cited by 28
Association of clinical competence, specialty and physician country of origin with opioid prescribing for chronic pain: a cohort study
Tamblyn, R. M., Girard, N., Boulet, J. R., Dauphinee, D. W., & Habib, B. (2021) · BMJ Quality & Safety · doi:10.1136/bmjqs-2021-013503 · Cited by 29
An Updated Overview of Low Back Pain Management
Hong, J., Song, K., Cho, J. H., Lee, J. H., & Kim, N. (2021) · Asian Spine Journal · doi:10.31616/asj.2021.0371 · Cited by 31
Activation of NK1receptors in the locus coeruleus induces analgesia through noradrenergic‐mediated descending inhibition in a rat model of neuropathic pain
Muto, Y., Sakai, A., Sakamoto, A., & Suzuki, H. (2011) · British Journal of Pharmacology · doi:10.1111/j.1476-5381.2011.01820.x · Cited by 28
Pharmacotherapeutic management of chronic noncancer pain in primary care: lessons for pharmacists
Lalonde, L., Jouini, G., Martin, É., Perreault, S., Berbiche, D., Lussier, D., Hudon, É., & Choinière, M. (2014) · Journal of Pain Research · doi:10.2147/jpr.s56884 · Cited by 28
Pain management in multiple myeloma
Niscola, P., Scaramucci, L., Romani, C., Giovannini, M., Tendas, A., Brunetti, G. A., Cartoni, C., Palumbo, R., Vischini, G., Siniscalchi, A., et al. (2010) · Expert Review of Anticancer Therapy · doi:10.1586/era.10.5 · Cited by 28
Acupuncture for neuropathic pain in adults
Ju, Z., Wang, K., Cui, H. S., Yao, Y., Liu, S. M., Zhou, J. J., Chen, T. Y., & Xia, J. (2016) · Cochrane Database of Systematic Reviews · doi:10.1002/14651858.cd012057 · Cited by 28
Gender and psychosocial context as determinants of fibromyalgia symptoms (fibromyalgia research criteria) in young adults from the general population
Lourenço, S., Costa, L. M. S. F., Rodrigues, A. M., Carnide, F., & Lucas, R. (2015) · Rheumatology · doi:10.1093/rheumatology/kev110 · Cited by 27
Pregabalin Reduces Opioid Consumption and Improves Outcome in Chronic Pain Patients Undergoing Total Knee Arthroplasty
Sawan, H., Chen, A. F., Viscusi, E. R., Parvizi, J., & Hozack, W. J. (2014) · The Physician and Sportsmedicine · doi:10.3810/psm.2014.05.2053 · Cited by 27
Drug safety evaluation of pregabalin
Toth, C. C. (2012) · Expert Opinion on Drug Safety · doi:10.1517/14740338.2012.677026 · Cited by 27
The effects of co-administration of pregabalin and vitamin E on neuropathic pain induced by partial sciatic nerve ligation in male rats
Meymandi, M. S., Sepehri, G., Abdolsamadi, M., Shaabani, M., Heravi, G., Yazdanpanah, O., & Aghtaei, M. M. (2017) · Inflammopharmacology · doi:10.1007/s10787-017-0325-4 · Cited by 27
Painful procedures
Adcock, S., & Tucker, C. B. (2018) · Elsevier eBooks · doi:10.1016/b978-0-08-100938-3.00008-5 · Cited by 27
Long Noncoding RNA SNHG5 Knockdown Alleviates Neuropathic Pain by Targeting the miR-154-5p/CXCL13 Axis
Mi, C., Yang, Y., Zhang, W., Li, X., Wu, J., Zou, X., & Zeng, X. (2020) · Neurochemical Research · doi:10.1007/s11064-020-03021-2 · Cited by 27
Pregabalin and Gabapentin in Patients with Spinal Cord Injury-Related Neuropathic Pain: A Network Meta-Analysis
Chen, T., Zhengyao, Z., Li, M., Su, D., Han, Q., & Fengqun, M. (2021) · Pain and Therapy · doi:10.1007/s40122-021-00302-8 · Cited by 27
Trigeminal nerve injury‐induced thrombospondin‐4 up‐regulation contributes to orofacial neuropathic pain states in a rat model
Li, K.-W., Kim, D., Zaucke, F., & Luo, Z. D. (2013) · European Journal of Pain · doi:10.1002/j.1532-2149.2013.00396.x · Cited by 27
Skin Matters: Identifying Pain Mechanisms and Predicting Treatment Outcomes
Shipton, E. A. (2013) · Neurology Research International · doi:10.1155/2013/329364 · Cited by 26
Headshaking in 5 Horses After Paranasal Sinus Surgery
Gilsenan, W. F., Getman, L. M., Parente, E. J., & Johnson, A. L. (2014) · Veterinary Surgery · doi:10.1111/j.1532-950x.2014.12147.x · Cited by 27
Etiology of Pain and Its Association with Quality of Life among Patients with Heart Failure
Pantilat, S. Z., O’Riordan, D. L., Rathfon, M. A., Dracup, K., & Marco, T. D. (2016) · Journal of Palliative Medicine · doi:10.1089/jpm.2016.0095 · Cited by 27
Evaluation of Primary Care Physician Chronic Pain Management Practice Patterns
Provenzano, D. A. (2018) · Pain Physician · doi:10.36076/ppj.2018.6.e593 · Cited by 27
Diagnosis and management of neuropathic pain: Review of literature and recommendations of the Polish Association for the Study of Pain and the Polish Neurological Society – Part one
Szczudlik, A., Dobrogowski, J., Wordliczek, J., Stępień, A., Krajnik, M., Leppert, W., Woroń, J., Przeklasa-Muszyńska, A., Kocot-Kępska, M., Zajączkowska, R., et al. (2014) · Neurologia i Neurochirurgia Polska · doi:10.1016/j.pjnns.2014.07.011 · Cited by 27
Synthesis, and anticonvulsant activity of new amides derived from 3-methyl- or 3-ethyl-3-methyl-2,5-dioxo-pyrrolidin-1-yl-acetic acids
Obniska, J., Rapacz, A., Rybka, S., Góra, M., Kamiński, K., Sałat, K., & Żmudzki, P. (2016) · Bioorganic & Medicinal Chemistry · doi:10.1016/j.bmc.2016.02.026 · Cited by 26
Efficacy and tolerability balance of oxycodone/naloxone and tapentadol in chronic low back pain with a neuropathic component: a blinded end point analysis of randomly selected routine data from 12-week prospective open-label observations
Ueberall, M. A., & Mueller-Schwefe, G. H. H. (2016) · Journal of Pain Research · doi:10.2147/jpr.s112418 · Cited by 26
Ameliorative Effects of Isoeugenol and Eugenol against Impaired Nerve Function and Inflammatory and Oxidative Mediators in Diabetic Neuropathic Rats
Alharthy, K. M., Balaha, M. F. H., Devi, S., Altharawi, A., Yusufoglu, H. S., Aldossari, R. M., Alam, A., & di Giacomo, V. (2023) · Biomedicines · doi:10.3390/biomedicines11041203 · Cited by 26
Neuropathic Pain Referrals to a Multidisciplinary Pediatric Cancer Pain Service
Anghelescu, D. L., Faughnan, L., Popenhagen, M. P., Oakes, L. L., Pei, D., & Burgoyne, L. L. (2012) · Pain Management Nursing · doi:10.1016/j.pmn.2012.07.006 · Cited by 26
Gabapentinoid Insensitivity after Repeated Administration is Associated with Down-Regulation of the α2δ-1 Subunit in Rats with Central Post-Stroke Pain Hypersensitivity
Yang, Y. L., Yang, F., Yang, F., Li, C.-L., Wang, Y., Li, Z., Lü, Y.-F., Yu, Y., Han, F., He, T., et al. (2016) · Neuroscience Bulletin · doi:10.1007/s12264-015-0008-3 · Cited by 26
Efficacy and Safety of Once-Daily Controlled-Release Pregabalin for the Treatment of Patients With Postherpetic Neuralgia
Huffman, C., Goldenberg, J. N., Weintraub, J., Sanin, L. C., Driscoll, J., Yang, R., Chew, M. L., & Scavone, J. M. (2016) · Clinical Journal of Pain · doi:10.1097/ajp.0000000000000445 · Cited by 26
Neuropathic pain responds better to increased doses of pregabalin: an in-depth analysis of flexible-dose clinical trials
Serpell, M. G., Latymer, M., Almas, M., Ortiz, M., Parsons, B., & Prieto, R. (2017) · Journal of Pain Research · doi:10.2147/jpr.s129832 · Cited by 26
Treatment of Neuropathic Pain with 5% Lidocaine‐Medicated Plaster: Five Years of Clinical Experience
Delorme, C., Navez, M. L., Legout, V., Deleens, R., & Moyse, D. (2011) · Pain Research and Management · doi:10.1155/2011/359591 · Cited by 26
Psychiatric aspects of pain disorder and its management.
Qureshi, S. F., Siddiqui, J. A., & Zahrani, A. A. (2017) · Journal of Behavioral Health · doi:10.5455/jbh.20170123102818 · Cited by 25
Outcome predictors for treatment success with 5% lidocaine medicated plaster in low back pain with neuropathic components and neuropathic pain after surgical and nonsurgical trauma
Hans, G. H., Nicolaou, Nicholson, N., & Brasseur, L. (2011) · Journal of Pain Research · doi:10.2147/jpr.s15534 · Cited by 25
Chronic Pain Prevalence and Exposures during Pregnancy
Ray-Griffith, S. L., Morrison, B., & Stowe, Z. N. (2019) · Pain Research and Management · doi:10.1155/2019/6985164 · Cited by 25
Combination therapy with extracorporeal shock wave and melatonin markedly attenuated neuropathic pain in rat.
Chen, K. H., Yang, C. H., Wallace, C. G., Lin, C., Liu, C.-K., Yin, T., Huang, T., Chen, Y., Sun, C., & Yip, H.-K. (2017) · PubMed Central · Cited by 25
circ‐ZNF609: A potent circRNA in human cancers
Qian, Y., Yang, L., Li, R., Yang, T., Jia, R.-P., & Ge, Y. (2021) · Journal of Cellular and Molecular Medicine · doi:10.1111/jcmm.16996 · Cited by 24
Role of Small-Fiber Afferents in Pain Mechanisms With Implications on Diagnosis and Treatment
Albrecht, P. J., & Rice, F. L. (2010) · Current Pain and Headache Reports · doi:10.1007/s11916-010-0105-y · Cited by 25
Preventive and Alleviative Effect of Tramadol on Neuropathic Pain in Rats: Roles of α2-Adrenoceptors and Spinal Astrocytes
Sakakiyama, M., Maeda, S., Isami, K., Asakura, K., So, K., Shirakawa, H., Nakagawa, T., & Kaneko, S. (2014) · Journal of Pharmacological Sciences · doi:10.1254/jphs.13223fp · Cited by 25
Neutrophils Infiltrate the Spinal Cord Parenchyma of Rats with Experimental Diabetic Neuropathy
Newton, V. L., Guck, J. D., Cotter, M. A., Cameron, N. E., & Gardiner, N. J. (2017) · Journal of Diabetes Research · doi:10.1155/2017/4729284 · Cited by 25

Authors: O'Connor, A. B., & Dworkin, R. H.
Affiliations: University of Rochester Medicine (US)
Corresponding author: O'Connor, Alec B.
ORCID: O'Connor, Alec B.
Dworkin, Robert H.
Venue: The American Journal of Medicine
Publisher: Elsevier BV
Published: 2009-10
Volume: 122
Issue: 10
Pages: S22-S32
ISSN: 0002-9343 (ISSN-L)
DOI: 10.1016/j.amjmed.2009.04.007
OpenAlex: W2092918915
Cited by: 781
References: 36
Citations by year: 2026: 9 · 2025: 19 · 2024: 16 · 2023: 21 · 2022: 29 · 2021: 29 · 2020: 23 · 2019: 38 · 2018: 33 · 2017: 50 · 2016: 73 · 2015: 77 · 2014: 73 · 2013: 91 · 2012: 67
FWCI: 7.23
Type: journal article
Language: en
Open access: closed
Licence: www.elsevier.com/tdm/userlicense/1.0/ (tdm)
www.elsevier.com/legal/tdmrep-license (tdm)
Locations: The American Journal of Medicine (publishedVersion)
PubMed (publishedVersion)
Topics: Health Sciences › Medicine › Physiology (medical) › Pain Mechanisms and Treatments
Health Sciences › Medicine › Anesthesiology and Pain Medicine › Pain Management and Treatment
Health Sciences › Medicine › Anesthesiology and Pain Medicine › Pain Management and Opioid Use
Keywords: neuropathic pain, pharmacotherapy, treatment guidelines, antidepressants, tricyclic antidepressants, serotonin-norepinephrine reuptake inhibitors, gabapentin, pregabalin, topical lidocaine, opioid analgesics, tramadol, antiepileptic drugs, topical capsaicin, mexiletine, NMDA receptor antagonists, neuromodulation, evidence-based medicine
MeSH terms: Pregabalin, Gabapentin, Amines, Analgesics, Analgesics, Opioid, Anesthetics, Local, Antidepressive Agents, Canada, Cyclohexanecarboxylic Acids, Europe, gamma-Aminobutyric Acid, Humans, International Cooperation, Lidocaine, Neuralgia, Societies, Medical, Tramadol, Selective Serotonin Reuptake Inhibitors, Practice Guidelines as Topic, Evidence-Based Medicine

About these checks

Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.

Statistics and arithmetic are recomputed, not judged.

Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.

What counts as a claim ›How we measure confidence ›How we check this ›

Are you an author, or do you see a problem with this page? Request a review

Treatment of neuropathic pain: an overview of recent guidelines.

Abstract

Overview

Integrity signals

Verification

Claims the paper makes

Claims other papers make about this one

Citations

Cites

Cited by

Related

Metadata

Record

About these checks