Cited by 244Dietary Effects on HealthNutritional Studies and DietDiet and metabolism studies

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Intermittent Fasting: A Heart Healthy Dietary Pattern?

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Dong, Tiffany A., Sandesara, Pratik B., Dhindsa, Devinder S., Mehta, Anurag, Arneson, Laura C., Dollar, Allen L., Taub, Pam R., Sperling, Laurence S.·2020·The American Journal of Medicine

DOI 10.1016/j.amjmed.2020.03.030PMC PMC7415631

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Abstract

Dietary patterns, such as the Dietary Approaches to Stop Hypertension (DASH) and the Mediterranean diet, have been shown to improve cardiac health. Intermittent fasting is another type of popular dietary pattern that is based on timed periods of fasting. Two different regimens are alternative day fasting and time-restricted eating. Although there are no large, randomized control trials examining the relationship between intermittent fasting and cardiovascular outcomes, current human studies that suggest this diet could reduce the risk for cardiovascular disease with improvement in weight control, hypertension, dyslipidemia, and diabetes. Intermittent fasting may exert its effects through multiple pathways, including reducing oxidative stress, optimization of circadian rhythms, and ketogenesis. This review evaluates current literature regarding the potential cardiovascular benefits of intermittent fasting and proposes directions for future research.

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Additional file 13 of The effect of calorie intake, fasting, and dietary composition on metabolic health and gut microbiota in mice
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Additional file 6 of The effect of calorie intake, fasting, and dietary composition on metabolic health and gut microbiota in mice
Zhang, Z., Chen, X., Loh, Y. J., Yang, X., & Zhang, C. (2021) · Figshare · doi:10.6084/m9.figshare.14251936
Additional file 5 of The effect of calorie intake, fasting, and dietary composition on metabolic health and gut microbiota in mice
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Additional file 8 of The effect of calorie intake, fasting, and dietary composition on metabolic health and gut microbiota in mice
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Additional file 14 of The effect of calorie intake, fasting, and dietary composition on metabolic health and gut microbiota in mice
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Additional file 16 of The effect of calorie intake, fasting, and dietary composition on metabolic health and gut microbiota in mice
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Additional file 4 of The effect of calorie intake, fasting, and dietary composition on metabolic health and gut microbiota in mice
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Additional file 11 of The effect of calorie intake, fasting, and dietary composition on metabolic health and gut microbiota in mice
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Additional file 15 of The effect of calorie intake, fasting, and dietary composition on metabolic health and gut microbiota in mice
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Authors: Dong, T. A., Sandesara, P. B., Dhindsa, D. S., Mehta, A., Arneson, L. C., Dollar, A. L., Taub, P. R., & Sperling, L. S.
Affiliations: Emory University (US)
Northwestern University (US)
University of California San Diego (US)
Corresponding author: Sperling, Laurence S.
ORCID: Dong, Tiffany A.
Sandesara, Pratik B.
Dhindsa, Devinder S.
Mehta, Anurag
Arneson, Laura C.
Taub, Pam R.
Sperling, Laurence S.
Venue: The American Journal of Medicine
Publisher: Elsevier BV
Published: 2020-08
Volume: 133
Issue: 8
Pages: 901-907
ISSN: 0002-9343 (ISSN-L)
DOI: 10.1016/j.amjmed.2020.03.030
PMC: PMC7415631
OpenAlex: W3018101566
Cited by: 240
References: 40
Citations by year: 2026: 14 · 2025: 43 · 2024: 50 · 2023: 44 · 2022: 38 · 2021: 47 · 2020: 4
FWCI: 4.40
Type: journal article
Language: en
Open access: green
www.ncbi.nlm.nih.gov
Licence: www.elsevier.com/tdm/userlicense/1.0/ (tdm)
www.elsevier.com/legal/tdmrep-license (tdm)
Locations: The American Journal of Medicine (publishedVersion)
PubMed (publishedVersion)
PubMed Central (acceptedVersion)
eScholarship (California Digital Library) (submittedVersion)
Funders: National Institute of Diabetes and Digestive and Kidney Diseases (R01DK118278)
Topics: Health Sciences › Medicine › Physiology (medical) › Dietary Effects on Health
Health Sciences › Medicine › Public Health, Environmental and Occupational Health › Nutritional Studies and Diet
Health Sciences › Medicine › Physiology (medical) › Diet and metabolism studies
Keywords: intermittent fasting, cardiovascular disease, time-restricted eating, dietary habits, hypertension, dyslipidemia, diabetes mellitus, weight management, oxidative stress, circadian rhythm, ketogenesis
MeSH terms: Cardiovascular Diseases, Circadian Rhythm, Diabetes Mellitus, Fasting, Humans, Hypertension, Ketone Bodies, Obesity, Risk Factors, Oxidative Stress, Risk Reduction Behavior, Dyslipidemias, Diet, Ketogenic

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Intermittent Fasting: A Heart Healthy Dietary Pattern?

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