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Cited by 34Pregnancy and Medication ImpactCardiovascular Issues in PregnancyAsthma and respiratory diseases

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Allergy Medications During Pregnancy

Gonzalez-Estrada, Alexei, Geraci, Stephen A.·2016·The American Journal of the Medical Sciences
DOI 10.1016/j.amjms.2016.05.030
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Abstract

Allergic diseases are common in women of childbearing age. Both asthma and atopic conditions may worsen, improve or remain the same during pregnancy. Primary care physicians commonly encounter women receiving multiple medications for pre-existing atopic conditions, who then become pregnant and require medication changes to avoid potential fetal injury or congenital malformations. Each medication should be evaluated; intranasal and inhaled steroids are relatively safe to continue during pregnancy (budesonide is the drug of choice), second-generation antihistamines of choice are cetirizine and loratadine, leukotriene receptor antagonists are safe, sparing use of oral decongestants during the first trimester and omalizumab may be used for both uncontrolled asthma and for antihistamine-resistant urticaria. Medications to avoid during pregnancy include intranasal antihistamines, first-generation antihistamines, mycophenolate mofetil, methotrexate, cyclosporine, azathioprine and zilueton. Common allergic diseases may develop de novo during pregnancy, such as anaphylaxis.

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Metadata

Authors
Gonzalez-Estrada, A., & Geraci, S. A.
Affiliations
East Tennessee State University (US)
Venue
The American Journal of the Medical Sciences
Publisher
Elsevier BV
Published
2016-09
Volume
352
Issue
3
Pages
326-331
ISSN
0002-9629 (ISSN-L)
DOI
10.1016/j.amjms.2016.05.030
OpenAlex
W2471531131
Cited by
34
References
5
Citations by year
2026: 1 · 2025: 1 · 2024: 1 · 2023: 4 · 2022: 9 · 2021: 4 · 2020: 5 · 2019: 5 · 2018: 1 · 2017: 3
FWCI
0.44
Type
journal article
Language
en
Open access
closed
Licence
www.elsevier.com/tdm/userlicense/1.0/ (tdm)
Locations
  • The American Journal of the Medical Sciences (publishedVersion)
  • PubMed (publishedVersion)
  • Digital Commons - East Tennessee State University (East Tennessee State University) (submittedVersion)
Topics
  • Health Sciences › Medicine › Public Health, Environmental and Occupational Health › Pregnancy and Medication Impact
  • Health Sciences › Medicine › Cardiology and Cardiovascular Medicine › Cardiovascular Issues in Pregnancy
  • Health Sciences › Medicine › Pulmonary and Respiratory Medicine › Asthma and respiratory diseases
Keywords
asthma in pregnancy, atopic diseases, intranasal corticosteroids, budesonide, second-generation antihistamines, cetirizine, loratadine, leukotriene receptor antagonists, oral decongestants, omalizumab, drug safety in pregnancy, congenital malformations, mycophenolate mofetil, methotrexate, cyclosporine, azathioprine, zileuton, anaphylaxis
MeSH terms
Asthma, Female, Histamine Antagonists, Humans, Hypersensitivity, Pregnancy, Pregnancy Complications, Nasal Decongestants, Anti-Allergic Agents

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