Omalizumab effectively prevents recurrent refractory anaphylaxis in a patient with monoclonal mast cell activation syndrome
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Response to additional drugs, including multitargeted tyrosine kinase inhibitors (in patients with SM, such as midostaurin) and anti-IgE therapy (omalizumab), may be considered an indirect sign of MCA or MCAS.
“Response to additional drugs, including multitargeted tyrosine kinase inhibitors (in patients with SM, such as midostaurin) and anti-IgE therapy (ie, omalizumab) may be considered an indirect sign of MCA or MCAS.”
From Selecting the Right Criteria and Proper Classification to Diagnose Mast Cell Activation Syndromes: A Critical Review (2021) · cites this paper as [82]
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“Response to additional drugs, including multitargeted tyrosine kinase inhibitors (in patients with SM, such as midostaurin) and anti-IgE therapy (ie, omalizumab) may be considered an indirect sign of MCA or MCAS.(80-88) Agents targeting growth and activation of neoplastic MCs, such as KIT-targeting kinase blockers, ar…”
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- Authors
- Jagdis, A., & Vadas, P.
- Affiliations
- St. Michael's Hospital (CA)
- Corresponding author
- Jagdis, Amanda
- ORCID
- Vadas, Peter
- Venue
- Annals of Allergy, Asthma & Immunology
- Publisher
- Elsevier BV
- Published
- 2014-07
- Volume
- 113
- Issue
- 1
- Pages
- 115-116
- ISSN
- 1081-1206 (ISSN-L)
- OpenAlex
- W2120848364
- Cited by
- 28
- References
- 10
- Citations by year
- 2026: 1 · 2025: 3 · 2024: 2 · 2021: 1 · 2020: 4 · 2019: 4 · 2018: 6 · 2017: 2 · 2016: 2 · 2015: 3
- FWCI
- 0.99
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- Annals of Allergy Asthma & Immunology (publishedVersion)
- PubMed (publishedVersion)
- Topics
- Life Sciences › Immunology and Microbiology › Immunology › Mast cells and histamine
- Health Sciences › Medicine › Immunology and Allergy › Food Allergy and Anaphylaxis Research
- Health Sciences › Medicine › Pharmacology › Drug-Induced Adverse Reactions
- Keywords
- omalizumab, anaphylaxis, refractory anaphylaxis, mast cell degranulation, mastocytosis, anti-IgE therapy, hypotension
- MeSH terms
- Omalizumab, Adult, Anaphylaxis, Antibodies, Anti-Idiotypic, Clone Cells, Female, Humans, Mast Cells, Recurrence, Syndrome, Cell Degranulation, Treatment Outcome, Anti-Allergic Agents, Antibodies, Monoclonal, Humanized
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